SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3a30 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE
(Escherichia
coli) 		4 / 7 PHE A  75
GLU A  83
ARG A  64
VAL A 132
 None
 1.19A 3dqrA-3a30A:
undetectable
3dqrB-3a30A:
undetectable		 3dqrA-3a30A:
18.33
3dqrB-3a30A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3a30 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE
(Escherichia
coli) 		4 / 8 THR A 183
ASN A 106
VAL A 143
ILE A 145
 None
 0.79A 4r38A-3a30A:
undetectable		 4r38A-3a30A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3a30 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE
(Escherichia
coli) 		3 / 3 HIS A  55
LYS A  56
PHE A  44
 None
 1.39A 5klaA-3a30A:
undetectable		 5klaA-3a30A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3a30 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE
(Escherichia
coli) 		3 / 3 ILE A 135
ASN A 106
CYH A 173
 None
 0.85A 6bp4A-3a30A:
undetectable		 6bp4A-3a30A:
20.32