SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		5 / 11 SER A  48
PHE A   2
VAL A  36
PHE A  28
VAL A  44
 DLZ  A 191 (-3.5A)
None
None
None
None
 1.43A 1q23L-3a3gA:
undetectable		 1q23L-3a3gA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		4 / 6 ASN A  82
ASN A  45
ILE A  12
THR A 171
 None
 1.20A 2hkkA-3a3gA:
undetectable		 2hkkA-3a3gA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		4 / 6 ASN A 141
ASN A  45
ILE A  26
THR A 171
 None
 1.14A 2hkkA-3a3gA:
undetectable		 2hkkA-3a3gA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		5 / 12 TYR A 159
GLY A  46
GLY A 100
LEU A  49
VAL A 143
 None
None
None
DLZ  A 191 (-4.2A)
None
 0.99A 2zulA-3a3gA:
undetectable		 2zulA-3a3gA:
16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		12 / 12 VAL A  41
CYH A  47
SER A  48
LEU A  49
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ASN A 101
ILE A 102
 DLZ  A 191 (-4.4A)
DLZ  A 191 (-3.6A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-4.2A)
DLZ  A 191 (-4.1A)
DLZ  A 191 (-3.9A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-3.4A)
DLZ  A 191 ( 4.6A)
DLZ  A 191 (-4.5A)
DLZ  A 191 (-4.1A)
 0.38A 3a35A-3a3gA:
35.3		 3a35A-3a3gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		12 / 12 VAL A  41
CYH A  47
SER A  48
LEU A  49
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ASN A 101
ILE A 102
 DLZ  A 191 (-4.4A)
DLZ  A 191 (-3.6A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-4.2A)
DLZ  A 191 (-4.1A)
DLZ  A 191 (-3.9A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-3.4A)
DLZ  A 191 ( 4.6A)
DLZ  A 191 (-4.5A)
DLZ  A 191 (-4.1A)
 0.44A 3a35B-3a3gA:
32.0		 3a35B-3a3gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		12 / 12 VAL A  41
CYH A  47
SER A  48
LEU A  49
THR A  50
ASP A  64
GLN A  65
ALA A  66
THR A  69
THR A  70
ASN A 101
ILE A 102
 DLZ  A 191 (-4.4A)
DLZ  A 191 (-3.6A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-4.2A)
DLZ  A 191 (-4.1A)
DLZ  A 191 (-3.9A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-3.4A)
DLZ  A 191 ( 4.6A)
DLZ  A 191 (-4.5A)
DLZ  A 191 (-4.1A)
 0.38A 3a3bA-3a3gA:
33.7		 3a3bA-3a3gA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		4 / 8 VAL A  41
GLY A 100
GLU A 181
GLY A 142
 DLZ  A 191 (-4.4A)
None
None
None
 0.75A 3aruA-3a3gA:
undetectable		 3aruA-3a3gA:
15.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		7 / 12 CYH A  47
ILE A  63
ASP A  64
GLN A  65
ALA A  66
ASN A 101
ILE A 102
 DLZ  A 191 (-3.6A)
DLZ  A 191 (-4.7A)
DLZ  A 191 (-3.9A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-4.5A)
DLZ  A 191 (-4.1A)
 0.92A 3ddyA-3a3gA:
29.2		 3ddyA-3a3gA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		10 / 12 VAL A  41
CYH A  47
SER A  48
THR A  50
ILE A  63
ASP A  64
GLN A  65
ALA A  66
THR A  69
ILE A 102
 DLZ  A 191 (-4.4A)
DLZ  A 191 (-3.6A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-4.1A)
DLZ  A 191 (-4.7A)
DLZ  A 191 (-3.9A)
DLZ  A 191 (-3.5A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-3.4A)
DLZ  A 191 (-4.1A)
 0.55A 3ddyA-3a3gA:
29.2		 3ddyA-3a3gA:
55.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		5 / 10 PHE A  61
PHE A  72
VAL A  81
ASN A  45
ILE A  32
 None
 1.36A 3t3qB-3a3gA:
undetectable		 3t3qB-3a3gA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		4 / 7 GLY A 142
ILE A 102
GLU A 181
GLN A   7
 None
DLZ  A 191 (-4.1A)
None
None
 1.09A 4g0vA-3a3gA:
undetectable		 4g0vA-3a3gA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		3 / 3 THR A  71
HIS A 137
LEU A  98
 None
 0.70A 5axdA-3a3gA:
undetectable		 5axdA-3a3gA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		3 / 3 THR A  71
HIS A 145
LEU A 169
 None
 0.61A 5axdA-3a3gA:
undetectable		 5axdA-3a3gA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		3 / 3 THR A  71
HIS A 137
LEU A  98
 None
 0.69A 5axdC-3a3gA:
undetectable		 5axdC-3a3gA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a3g LUMAZINE PROTEIN
(Photobacterium
kishitanii) 		3 / 3 THR A  71
HIS A 145
LEU A 169
 None
 0.62A 5axdC-3a3gA:
undetectable		 5axdC-3a3gA:
19.12