SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 PHE A 251
TRP A 248
GLU A 244
 None
 0.99A 1mogA-3a3hA:
undetectable		 1mogA-3a3hA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 10 THR A 175
PHE A 199
LEU A 218
PHE A 251
VAL A 214
 None
 1.46A 1q23E-3a3hA:
undetectable		 1q23E-3a3hA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 ASN A 138
GLU A 139
HIS A 200
GLU A 228
TRP A 262
 CTR  A   1 (-3.1A)
CTR  A   1 ( 2.4A)
None
CTR  A   1 ( 2.7A)
CTR  A   1 (-3.5A)
 0.55A 2v3dA-3a3hA:
16.1		 2v3dA-3a3hA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 5 VAL A  60
TYR A  95
VAL A   5
ASP A  93
 None
 1.29A 2x45A-3a3hA:
undetectable		 2x45A-3a3hA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 5 VAL A  60
TYR A  95
VAL A   5
ASP A  93
 None
 1.28A 2x45C-3a3hA:
undetectable		 2x45C-3a3hA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 ARG A  62
GLU A 135
TYR A 202
ASN A 138
HIS A 101
 None
None
CTR  A   1 (-4.5A)
CTR  A   1 (-3.1A)
CTR  A   1 (-4.0A)
 1.49A 3bjmA-3a3hA:
undetectable		 3bjmA-3a3hA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 ARG A  62
GLU A 135
TYR A 202
ASN A 138
HIS A 101
 None
None
CTR  A   1 (-4.5A)
CTR  A   1 (-3.1A)
CTR  A   1 (-4.0A)
 1.45A 3bjmB-3a3hA:
undetectable		 3bjmB-3a3hA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 11 ARG A  62
TYR A  95
VAL A   6
PRO A 130
ILE A 170
 None
 1.32A 3ganA-3a3hA:
undetectable		 3ganA-3a3hA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 HIS A 101
PHE A 118
PHE A 119
 CTR  A   1 (-4.0A)
None
None
 0.57A 3lk0D-3a3hA:
undetectable		 3lk0D-3a3hA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 ASP A 117
ILE A 161
VAL A  82
ILE A 162
ALA A 115
 None
 1.22A 3ohtA-3a3hA:
undetectable
3ohtB-3a3hA:
undetectable		 3ohtA-3a3hA:
19.29
3ohtB-3a3hA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 8 PRO A 140
HIS A 101
ILE A 102
ILE A 136
 None
CTR  A   1 (-4.0A)
None
None
 0.88A 3sfeB-3a3hA:
undetectable
3sfeC-3a3hA:
undetectable		 3sfeB-3a3hA:
19.57
3sfeC-3a3hA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 10 THR A 175
PHE A 199
LEU A 218
PHE A 251
VAL A 214
 None
 1.44A 3u9fI-3a3hA:
undetectable		 3u9fI-3a3hA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 6 HIS A 200
GLU A 228
ASP A  99
SER A  33
 None
CTR  A   1 ( 2.7A)
None
None
 1.08A 4apjA-3a3hA:
undetectable
4apjP-3a3hA:
undetectable		 4apjA-3a3hA:
19.90
4apjP-3a3hA:
4.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 LEU A 264
SER A  34
TRP A  56
GLY A  31
ALA A 260
 None
 1.15A 4coxC-3a3hA:
undetectable		 4coxC-3a3hA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 8 VAL A   5
HIS A   9
LEU A  19
LEU A  12
 None
 1.11A 4jtrA-3a3hA:
10.1		 4jtrA-3a3hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 PHE A 201
GLU A 139
ALA A 198
ALA A 260
ALA A  64
 None
CTR  A   1 ( 2.4A)
None
None
None
 1.05A 4oaeA-3a3hA:
undetectable		 4oaeA-3a3hA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 LEU A 264
SER A  34
TRP A  56
GLY A  31
ALA A 260
 None
 1.10A 4otyA-3a3hA:
undetectable		 4otyA-3a3hA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 LEU A 264
SER A  34
TRP A  56
GLY A  31
ALA A 260
 None
 1.08A 4otyB-3a3hA:
undetectable		 4otyB-3a3hA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 5 HIS A   9
VAL A   6
GLU A   8
VAL A  27
 None
 1.26A 4p6vB-3a3hA:
undetectable
4p6vE-3a3hA:
undetectable		 4p6vB-3a3hA:
19.57
4p6vE-3a3hA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 9 ALA A 203
THR A 231
ALA A 245
GLY A 238
GLY A 239
 None
 1.12A 4qwuK-3a3hA:
undetectable
4qwuL-3a3hA:
undetectable		 4qwuK-3a3hA:
20.65
4qwuL-3a3hA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 9 ALA A 203
THR A 231
ALA A 245
GLY A 238
GLY A 239
 None
 1.15A 4qwuY-3a3hA:
undetectable
4qwuZ-3a3hA:
undetectable		 4qwuY-3a3hA:
20.65
4qwuZ-3a3hA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 4 THR A 265
GLY A 236
ASP A 237
SER A 263
 None
CTR  A   1 (-3.5A)
None
None
 1.34A 4rfqA-3a3hA:
undetectable		 4rfqA-3a3hA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 LEU A 264
SER A  34
TRP A  56
GLY A  31
ALA A 260
 None
 1.06A 4rrwD-3a3hA:
undetectable		 4rrwD-3a3hA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 12 LEU A 264
SER A  34
TRP A  56
GLY A  31
ALA A 260
 None
 1.06A 4rrzD-3a3hA:
undetectable		 4rrzD-3a3hA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 MET A 196
GLN A 220
TYR A 216
 None
 1.05A 4udcA-3a3hA:
undetectable		 4udcA-3a3hA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 TYR A  46
ARG A  53
LYS A  50
 None
 1.34A 4wq5B-3a3hA:
undetectable		 4wq5B-3a3hA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 ARG A 297
ASP A  55
TRP A  56
 None
 1.19A 4xdqA-3a3hA:
undetectable		 4xdqA-3a3hA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 9 SER A  33
GLY A 174
SER A 179
GLU A 139
ALA A 155
 None
None
None
CTR  A   1 ( 2.4A)
None
 1.37A 5entC-3a3hA:
undetectable		 5entC-3a3hA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 6 GLY A 230
THR A 231
SER A 232
ASN A 261
 None
 0.88A 5k4pA-3a3hA:
undetectable		 5k4pA-3a3hA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 PHE A 251
ASP A 253
LEU A 242
 None
 0.79A 5uhbC-3a3hA:
undetectable		 5uhbC-3a3hA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 PHE A 251
ASP A 253
LEU A 242
 None
 0.74A 5uhcC-3a3hA:
undetectable		 5uhcC-3a3hA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 6 ILE A  58
ILE A 170
LEU A  12
HIS A   9
 None
 1.04A 5vkqB-3a3hA:
undetectable
5vkqC-3a3hA:
undetectable		 5vkqB-3a3hA:
10.04
5vkqC-3a3hA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		4 / 6 ILE A  58
ILE A 170
LEU A  12
HIS A   9
 None
 1.02A 5vkqC-3a3hA:
undetectable
5vkqD-3a3hA:
undetectable		 5vkqC-3a3hA:
10.04
5vkqD-3a3hA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		5 / 10 SER A 292
GLY A 293
ILE A  58
LEU A 264
PHE A 118
 None
 1.27A 5zjiA-3a3hA:
undetectable
5zjiJ-3a3hA:
undetectable		 5zjiA-3a3hA:
15.50
5zjiJ-3a3hA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3a3h ENDOGLUCANASE
(Salipaludibacill
us
agaradhaerens) 		3 / 3 ASN A 131
VAL A  27
HIS A   9
 None
 0.78A 6a5yD-3a3hA:
undetectable		 6a5yD-3a3hA:
12.00