SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.39A 1ghmA-3a3iA:
20.6		 1ghmA-3a3iA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 356
GLY A 359
VAL A  77
ALA A 339
LEU A 338
 None
 1.02A 1gs4A-3a3iA:
undetectable		 1gs4A-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		8 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.47A 1i2wA-3a3iA:
20.9		 1i2wA-3a3iA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-3.4A)
 0.51A 1i2wB-3a3iA:
21.0		 1i2wB-3a3iA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 PHE A 393
SER A 375
PHE A 351
LEU A 344
ALA A  76
 None
 1.35A 1q23D-3a3iA:
undetectable
1q23E-3a3iA:
undetectable		 1q23D-3a3iA:
17.54
1q23E-3a3iA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLY A  44
ILE A 448
GLN A 446
VAL A  30
 None
 0.88A 1rs7B-3a3iA:
undetectable		 1rs7B-3a3iA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.52A 1ymxA-3a3iA:
20.7		 1ymxA-3a3iA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.74A 1ymxB-3a3iA:
20.7		 1ymxB-3a3iA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 PHE A 112
LEU A 123
LEU A  93
LEU A 108
 None
 1.00A 2bfpC-3a3iA:
undetectable		 2bfpC-3a3iA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 PHE A 112
LEU A 123
LEU A  93
LEU A 108
 None
 1.02A 2bfpD-3a3iA:
undetectable		 2bfpD-3a3iA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ALA A 252
ASN A 232
VAL A 228
ASN A 168
PRO A 170
 None
 0.92A 2okcB-3a3iA:
undetectable		 2okcB-3a3iA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 356
GLY A 359
VAL A  77
ALA A 339
LEU A 338
 None
 0.91A 2oz7A-3a3iA:
undetectable		 2oz7A-3a3iA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 TYR A 182
GLY A 248
PRO A 246
GLU A 184
 None
 1.00A 2ys6A-3a3iA:
undetectable		 2ys6A-3a3iA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 1.17A 3ablP-3a3iA:
undetectable
3ablW-3a3iA:
undetectable		 3ablP-3a3iA:
20.00
3ablW-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 SER A 310
THR A 401
ALA A 431
ALA A 419
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
None
None
 1.00A 3ax9B-3a3iA:
1.8		 3ax9B-3a3iA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.41A 3hlwA-3a3iA:
20.7		 3hlwA-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.22A 3hlwB-3a3iA:
20.9		 3hlwB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.73A 3hlwB-3a3iA:
20.9		 3hlwB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.42A 3huoA-3a3iA:
20.7		 3huoA-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.92A 3huoB-3a3iA:
20.8		 3huoB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
ASN A 312
LEU A 362
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 (-4.9A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.73A 3mzeA-3a3iA:
18.2		 3mzeA-3a3iA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 SER A 310
THR A 401
ALA A 431
ALA A 419
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
None
None
 0.94A 3ns1L-3a3iA:
undetectable		 3ns1L-3a3iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.52A 3ny4A-3a3iA:
19.5		 3ny4A-3a3iA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.30A 3q07A-3a3iA:
20.7		 3q07A-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.81A 3q07B-3a3iA:
20.8		 3q07B-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.21A 3sh8A-3a3iA:
20.9		 3sh8A-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.29A 3sh8B-3a3iA:
21.0		 3sh8B-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLY A  44
ILE A 448
GLN A 446
VAL A  30
 None
 0.92A 4d39B-3a3iA:
undetectable		 4d39B-3a3iA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.62A 4euzA-3a3iA:
19.4		 4euzA-3a3iA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 10 SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
ALA A  68
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.6A)
 1.47A 4fh2A-3a3iA:
21.4		 4fh2A-3a3iA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		3 / 3 ASP A 257
ARG A 154
THR A 146
 None
 0.90A 4i13A-3a3iA:
undetectable		 4i13A-3a3iA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLY A  44
ILE A 448
GLN A 446
VAL A  30
 None
 0.86A 4kcnA-3a3iA:
undetectable		 4kcnA-3a3iA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 4n9kA-3a3iA:
21.0		 4n9kA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
ASN A 312
LYS A 420
THR A 421
GLY A 422
TYR A 428
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
None
 0.87A 4n9kB-3a3iA:
21.0		 4n9kB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 4n9kB-3a3iA:
21.0		 4n9kB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		3 / 3 ASP A 257
ARG A 154
THR A 146
 None
 0.89A 4p3rA-3a3iA:
undetectable		 4p3rA-3a3iA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		3 / 3 THR A 256
ASN A 312
PHE A 167
 None
AIX  A 501 (-3.3A)
AIX  A 501 (-3.6A)
 0.84A 4pd9A-3a3iA:
undetectable		 4pd9A-3a3iA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.70A 4pm5A-3a3iA:
20.6		 4pm5A-3a3iA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.91A 4pm5A-3a3iA:
20.6		 4pm5A-3a3iA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.45A 4pm7A-3a3iA:
20.6		 4pm7A-3a3iA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.22A 4pm9A-3a3iA:
20.7		 4pm9A-3a3iA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ILE A 409
THR A  70
THR A 421
LEU A 408
LEU A 465
 None
None
AIX  A 501 (-3.4A)
None
None
 1.34A 4qynB-3a3iA:
undetectable		 4qynB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ILE A 409
THR A  70
THR A 421
LEU A 408
LEU A 465
 None
None
AIX  A 501 (-3.4A)
None
None
 1.34A 4qzuA-3a3iA:
undetectable		 4qzuA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 1.17A 5b1bC-3a3iA:
undetectable
5b1bJ-3a3iA:
undetectable		 5b1bC-3a3iA:
20.00
5b1bJ-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
ASN A 312
LYS A 420
GLY A 422
TYR A 428
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
None
 0.96A 5ghyA-3a3iA:
20.8		 5ghyA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.22A 5ghyA-3a3iA:
20.8		 5ghyA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.19A 5ghyB-3a3iA:
20.7		 5ghyB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 11 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.24A 5ghzA-3a3iA:
21.0		 5ghzA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 10 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 5ghzB-3a3iA:
20.9		 5ghzB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 10 MET A 306
LEU A 389
VAL A 376
ILE A 343
LEU A 344
 None
 1.16A 5ienB-3a3iA:
undetectable		 5ienB-3a3iA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 413
LEU A 408
GLY A 407
GLY A 406
LEU A 472
 None
 0.92A 5uc1A-3a3iA:
undetectable		 5uc1A-3a3iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 413
LEU A 408
GLY A 407
GLY A 406
VAL A 466
 None
 0.92A 5uc1A-3a3iA:
undetectable		 5uc1A-3a3iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 413
LEU A 408
GLY A 407
GLY A 406
LEU A 472
 None
 0.92A 5uc1B-3a3iA:
undetectable		 5uc1B-3a3iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LEU A 413
LEU A 408
GLY A 407
GLY A 406
VAL A 466
 None
 0.93A 5uc1B-3a3iA:
undetectable		 5uc1B-3a3iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 7 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.78A 5z84C-3a3iA:
undetectable
5z84J-3a3iA:
undetectable		 5z84C-3a3iA:
20.00
5z84J-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.78A 5z84P-3a3iA:
undetectable
5z84W-3a3iA:
undetectable		 5z84P-3a3iA:
20.00
5z84W-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 7 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.76A 5z85C-3a3iA:
undetectable
5z85J-3a3iA:
undetectable		 5z85C-3a3iA:
20.00
5z85J-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.83A 5z85P-3a3iA:
undetectable
5z85W-3a3iA:
undetectable		 5z85P-3a3iA:
20.00
5z85W-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.80A 5z86C-3a3iA:
undetectable
5z86J-3a3iA:
undetectable		 5z86C-3a3iA:
20.00
5z86J-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.78A 5z86P-3a3iA:
undetectable
5z86W-3a3iA:
undetectable		 5z86P-3a3iA:
20.00
5z86W-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 7 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.70A 5zcoC-3a3iA:
undetectable
5zcoJ-3a3iA:
undetectable		 5zcoC-3a3iA:
20.00
5zcoJ-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.78A 5zcoP-3a3iA:
undetectable
5zcoW-3a3iA:
undetectable		 5zcoP-3a3iA:
20.00
5zcoW-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.73A 5zcpC-3a3iA:
undetectable
5zcpJ-3a3iA:
undetectable		 5zcpC-3a3iA:
20.00
5zcpJ-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 6 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.77A 5zcpP-3a3iA:
undetectable
5zcpW-3a3iA:
undetectable		 5zcpP-3a3iA:
20.00
5zcpW-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 7 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.79A 5zcqC-3a3iA:
undetectable
5zcqJ-3a3iA:
undetectable		 5zcqC-3a3iA:
20.00
5zcqJ-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 7 GLN A 235
PHE A 251
LEU A 249
PHE A 247
 None
 0.76A 5zcqP-3a3iA:
undetectable
5zcqW-3a3iA:
undetectable		 5zcqP-3a3iA:
20.00
5zcqW-3a3iA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.44A 6b5yB-3a3iA:
20.2		 6b5yB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.50A 6b5yD-3a3iA:
20.1		 6b5yD-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.27A 6b68B-3a3iA:
20.1		 6b68B-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.37A 6b68D-3a3iA:
20.1		 6b68D-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 6b69A-3a3iA:
20.0
6b69B-3a3iA:
19.9		 6b69A-3a3iA:
12.53
6b69B-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 6b69D-3a3iA:
20.1		 6b69D-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.30A 6b6aB-3a3iA:
20.2		 6b6aB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 6b6aD-3a3iA:
20.2		 6b6aD-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.40A 6b6cA-3a3iA:
19.8		 6b6cA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.60A 6b6dA-3a3iA:
20.0		 6b6dA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.33A 6b6eA-3a3iA:
20.0		 6b6eA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.53A 6b6fA-3a3iA:
19.5		 6b6fA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.67A 6c79A-3a3iA:
20.5		 6c79A-3a3iA:
13.24