SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 5 HIS A 238
LEU A 175
LEU A 135
GLY A   4
 None
 1.08A 1a4lB-3a45A:
undetectable		 1a4lB-3a45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 6 LEU A  14
TRP A  88
PHE A  64
VAL A  52
 None
 1.32A 1ibgH-3a45A:
undetectable		 1ibgH-3a45A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 4 LEU A  23
SER A 101
TYR A  25
LEU A  48
 None
 1.19A 1xz1A-3a45A:
undetectable		 1xz1A-3a45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 4 LEU A  23
SER A 101
TYR A  25
LEU A  48
 None
 1.18A 1xz3A-3a45A:
undetectable		 1xz3A-3a45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 6 LEU A 202
LYS A 207
ILE A 179
ILE A 157
 None
 0.84A 2piwA-3a45A:
undetectable		 2piwA-3a45A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 ILE A 206
LEU A 202
ILE A 179
ILE A 150
PHE A 139
 None
 1.09A 2ygnA-3a45A:
undetectable		 2ygnA-3a45A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		3 / 3 SER A 101
GLU A  92
ASP A  27
 None
 0.74A 2zthA-3a45A:
undetectable		 2zthA-3a45A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		3 / 3 SER A 101
GLU A  92
ASP A  27
 None
 0.81A 3bwyA-3a45A:
undetectable		 3bwyA-3a45A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 ALA A  11
GLY A   4
GLY A  59
LEU A 171
GLU A 209
 None
 1.11A 4lg1A-3a45A:
undetectable		 4lg1A-3a45A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 ALA A  11
GLY A   4
GLY A  59
LEU A 171
GLU A 209
 None
 1.06A 4lg1B-3a45A:
undetectable		 4lg1B-3a45A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		3 / 3 SER A 101
GLU A  92
ASP A  27
 None
 0.83A 4xudA-3a45A:
undetectable		 4xudA-3a45A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 6 ILE A 285
VAL A 264
ASP A 258
PRO A 259
ALA A 282
 None
 1.28A 5cu6A-3a45A:
undetectable		 5cu6A-3a45A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 11 ILE A 167
ILE A 145
VAL A 176
VAL A 158
LEU A 202
 None
 1.32A 5jkwA-3a45A:
undetectable		 5jkwA-3a45A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 7 ILE A 285
VAL A 264
ASP A 258
PRO A 259
ALA A 282
 None
 1.29A 5ospA-3a45A:
undetectable		 5ospA-3a45A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		3 / 3 ILE A 270
VAL A 158
PRO A 187
 None
 0.59A 5uunA-3a45A:
undetectable		 5uunA-3a45A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 6 TYR A 109
LEU A  14
GLU A 228
LEU A 225
 None
 1.41A 5xooA-3a45A:
undetectable		 5xooA-3a45A:
15.38