SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		4 / 8 VAL A  30
TYR A  50
GLY A  31
TYR A 196
 None
 1.01A 1jlfA-3a55A:
undetectable
1jlfB-3a55A:
undetectable		 1jlfA-3a55A:
20.56
1jlfB-3a55A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 ASN A 272
PHE A 280
VAL A 294
 None
 0.86A 1kijA-3a55A:
undetectable		 1kijA-3a55A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		4 / 7 VAL A  30
TYR A  50
GLY A  31
TYR A 196
 None
 1.01A 1lweA-3a55A:
undetectable		 1lweA-3a55A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 TYR A 157
VAL A 276
THR A  46
 None
 0.83A 2ygnA-3a55A:
undetectable		 2ygnA-3a55A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 TYR A 196
ASP A 154
ASP A 293
 None
 0.79A 3ou6B-3a55A:
undetectable		 3ou6B-3a55A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 GLU A  85
GLY A  87
SER A  83
 None
 0.69A 4b53B-3a55A:
undetectable		 4b53B-3a55A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		5 / 12 GLN A  48
LEU A  45
GLY A 155
ALA A 158
PHE A 280
 None
 1.21A 4retA-3a55A:
undetectable		 4retA-3a55A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		5 / 12 GLN A  48
LEU A  45
GLY A 155
ALA A 158
PHE A 280
 None
 1.21A 4retC-3a55A:
undetectable		 4retC-3a55A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR A 139
HIS A 161
LEU A 277
 None
 0.79A 5axdC-3a55A:
undetectable		 5axdC-3a55A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR A 211
SER A 203
ASP A 228
 None
 0.72A 5kvaA-3a55A:
undetectable		 5kvaA-3a55A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		3 / 3 THR A 211
SER A 203
ASP A 228
 None
 0.73A 5kvaB-3a55A:
undetectable		 5kvaB-3a55A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3a55 PROTEIN-GLUTAMINASE
(Chryseobacterium
proteolyticum) 		4 / 6 GLY A 188
THR A 189
ARG A 150
SER A 284
 None
 1.09A 6jogA-3a55A:
undetectable		 6jogA-3a55A:
18.36