SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_D_30BD500_2 (GENOME POLYPROTEIN)	3a57	THERMOSTABLE DIRECT HEMOLYSIN 2 (Vibrio parahaemolyticus)	4 / 4	PHE A 38 TYR A 49 VAL A 137 LEU A 148	None	1.48A	3keeD-3a57A: undetectable	3keeD-3a57A: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	3a57	THERMOSTABLE DIRECT HEMOLYSIN 2 (Vibrio parahaemolyticus)	3 / 3	GLY A 62 GLU A 15 THR A 60	None	0.59A	4kouA-3a57A: undetectable	4kouA-3a57A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_D_AERD601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3a57	THERMOSTABLE DIRECT HEMOLYSIN 2 (Vibrio parahaemolyticus)	4 / 5	TYR A 140 GLY A 145 ASP A 14 VAL A 110	None	1.11A	4nkvD-3a57A: undetectable	4nkvD-3a57A: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBF_A_ACTA507_0 (MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1)	3a57	THERMOSTABLE DIRECT HEMOLYSIN 2 (Vibrio parahaemolyticus)	3 / 3	LYS A 12 SER A 85 SER A 92	None	0.97A	6gbfA-3a57A: undetectable	6gbfA-3a57A: 15.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KEE_D_30BD500_2","GENOME POLYPROTEIN","3a57","THERMOSTABLE DIRECT HEMOLYSIN 2","Vibrio parahaemolyticus",4,"PHE A  38;TYR A  49;VAL A 137;LEU A 148","None","1.48A","3keeD-3a57A:undetectable","3keeD-3a57A:20.81"],["4KOU_A_C04A207_1","UNCHARACTERIZED PROTEIN","3a57","THERMOSTABLE DIRECT HEMOLYSIN 2","Vibrio parahaemolyticus",3,"GLY A  62;GLU A  15;THR A  60","None","0.59A","4kouA-3a57A:undetectable","4kouA-3a57A:16.67"],["4NKV_D_AERD601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3a57","THERMOSTABLE DIRECT HEMOLYSIN 2","Vibrio parahaemolyticus",4,"TYR A 140;GLY A 145;ASP A  14;VAL A 110","None","1.11A","4nkvD-3a57A:undetectable","4nkvD-3a57A:15.69"],["6GBF_A_ACTA507_0","MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1","3a57","THERMOSTABLE DIRECT HEMOLYSIN 2","Vibrio parahaemolyticus",3,"LYS A  12;SER A  85;SER A  92","None","0.97A","6gbfA-3a57A:undetectable","6gbfA-3a57A:15.94"]]