SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 3a5x FLAGELLIN
(Salmonella
enterica) 		4 / 8 VAL A 418
LEU A 167
SER A 126
VAL A 125
 None
 0.99A 1jtvA-3a5xA:
undetectable		 1jtvA-3a5xA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 3a5x FLAGELLIN
(Salmonella
enterica) 		5 / 12 ALA A 413
LEU A  88
GLN A  89
ILE A 162
LEU A  81
 None
 1.26A 3ia4B-3a5xA:
undetectable		 3ia4B-3a5xA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3a5x FLAGELLIN
(Salmonella
enterica) 		4 / 6 TYR A 229
VAL A 278
THR A 226
THR A 225
 None
 0.94A 3tneA-3a5xA:
undetectable		 3tneA-3a5xA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 3a5x FLAGELLIN
(Salmonella
enterica) 		5 / 12 LEU A 415
ILE A  84
LEU A 421
ARG A 422
GLY A  79
 None
 1.13A 4l9qA-3a5xA:
2.1		 4l9qA-3a5xA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_B_GLYB404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3a5x FLAGELLIN
(Salmonella
enterica) 		4 / 4 GLN A 429
ALA A  74
GLN A  75
THR A  77
 None
 1.35A 5hhjB-3a5xA:
0.0		 5hhjB-3a5xA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3a5x FLAGELLIN
(Salmonella
enterica) 		3 / 3 GLY A 237
GLY A 238
GLN A 214
 None
 0.46A 5imsA-3a5xA:
undetectable		 5imsA-3a5xA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3a5x FLAGELLIN
(Salmonella
enterica) 		3 / 3 GLY A 218
ASP A 219
ASN A 280
 None
 0.48A 5jglA-3a5xA:
undetectable		 5jglA-3a5xA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3a5x FLAGELLIN
(Salmonella
enterica) 		5 / 12 GLU A 290
ASP A 339
GLY A 340
LEU A 323
ALA A 185
 None
 1.30A 5kbwA-3a5xA:
2.6		 5kbwA-3a5xA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 3a5x FLAGELLIN
(Salmonella
enterica) 		3 / 3 ARG A 422
PHE A 131
LEU A 137
 None
 0.80A 5veuA-3a5xA:
undetectable		 5veuA-3a5xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3a5x FLAGELLIN
(Salmonella
enterica) 		3 / 3 LEU A 266
GLY A 243
PHE A 202
 None
 0.62A 6exiC-3a5xA:
undetectable		 6exiC-3a5xA:
11.75