SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 ILE A 191
ILE A 129
TYR A 125
LEU A 152
 None
 0.90A 3adsA-3a64A:
undetectable		 3adsA-3a64A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 VAL A 126
VAL A 130
LEU A 133
SER A 134
 None
 0.90A 3hs6B-3a64A:
undetectable		 3hs6B-3a64A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		3 / 3 GLU A 362
GLY A 335
THR A 336
 None
 0.59A 3iazA-3a64A:
undetectable		 3iazA-3a64A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 11 GLY A 283
ILE A 290
VAL A  53
LEU A 379
GLY A 306
 None
 1.05A 3zosA-3a64A:
undetectable
3zosB-3a64A:
undetectable		 3zosA-3a64A:
24.32
3zosB-3a64A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 8 ALA A 209
SER A 208
LEU A 231
TYR A 261
 None
 1.17A 4ijiF-3a64A:
undetectable		 4ijiF-3a64A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 8 GLU A 258
ASP A 281
SER A 285
PRO A 240
 None
 0.89A 4uhxA-3a64A:
undetectable		 4uhxA-3a64A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 8 GLU A 258
ASP A 281
SER A 285
PRO A 240
 None
 0.89A 4uhxA-3a64A:
undetectable		 4uhxA-3a64A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 6 GLN A 270
PHE A 278
LEU A 231
PHE A 212
 None
 1.17A 5b1bC-3a64A:
undetectable
5b1bJ-3a64A:
undetectable		 5b1bC-3a64A:
18.84
5b1bJ-3a64A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 7 GLN A  54
PHE A 305
LEU A 371
PHE A 367
 None
 0.97A 5b3sC-3a64A:
undetectable
5b3sJ-3a64A:
undetectable		 5b3sC-3a64A:
18.84
5b3sJ-3a64A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		4 / 5 ILE A  71
LYS A  25
ILE A  24
VAL A  91
 None
 1.02A 5jmnA-3a64A:
undetectable		 5jmnA-3a64A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 LEU A  22
LEU A  93
THR A  67
ILE A  75
ILE A  71
 None
 1.27A 5nm5B-3a64A:
2.8		 5nm5B-3a64A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3a64 CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		3 / 3 THR A 157
MET A 159
HIS A 160
 None
 0.81A 5uunA-3a64A:
undetectable		 5uunA-3a64A:
22.25