SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		6 / 12 PHE A  84
ALA A 132
ILE A 181
SER A 138
PHE A  83
LEU A 204
 None
 1.38A 1xdkF-3a68A:
undetectable		 1xdkF-3a68A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		3 / 3 PRO A  32
THR A  30
PRO A  29
 None
 0.83A 2d55C-3a68A:
undetectable		 2d55C-3a68A:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 12 LEU A 204
MET A 203
PHE A 200
GLN A 187
ALA A 186
 None
 1.48A 2jj8C-3a68A:
undetectable		 2jj8C-3a68A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 10 VAL A 197
GLY A 194
GLY A  79
LEU A  80
ALA A 129
 None
 0.97A 2v3kA-3a68A:
undetectable		 2v3kA-3a68A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		4 / 7 GLU A  91
GLU A 140
PHE A  83
TYR A  63
 CA  A 214 (-2.4A)
CA  A 214 ( 4.6A)
None
None
 0.92A 3ku9B-3a68A:
undetectable		 3ku9B-3a68A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 12 ILE A 181
LEU A 142
VAL A  59
THR A 143
MET A  66
 None
None
None
CA  A 214 ( 4.4A)
None
 1.22A 5bykA-3a68A:
undetectable		 5bykA-3a68A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 12 LEU A 171
GLY A 172
ASN A 144
GLU A  56
LEU A 148
 None
CA  A 215 ( 4.6A)
None
CA  A 214 (-2.9A)
None
 1.04A 5czyA-3a68A:
undetectable		 5czyA-3a68A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 12 PHE A  84
ALA A 132
ILE A 181
SER A 138
PHE A  83
 None
 1.02A 5m24A-3a68A:
undetectable		 5m24A-3a68A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 3a68 FERRITIN-4,
CHLOROPLASTIC
(Glycine
max) 		5 / 10 ILE A 181
LEU A 142
VAL A  59
THR A 143
MET A  66
 None
None
None
CA  A 214 ( 4.4A)
None
 1.16A 6b4yA-3a68A:
0.0		 6b4yA-3a68A:
20.00