SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3a69 FLAGELLAR HOOK
PROTEIN FLGE
(Salmonella
enterica) 		4 / 7 TYR A 210
HIS A 212
PRO A 222
TYR A 198
 None
 1.05A 2ombC-3a69A:
undetectable
2ombD-3a69A:
undetectable		 2ombC-3a69A:
21.13
2ombD-3a69A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3a69 FLAGELLAR HOOK
PROTEIN FLGE
(Salmonella
enterica) 		5 / 11 SER A  94
LEU A  72
ASP A  73
LEU A 107
ILE A 293
 None
 1.16A 3ko0A-3a69A:
undetectable
3ko0B-3a69A:
undetectable
3ko0I-3a69A:
undetectable
3ko0J-3a69A:
undetectable		 3ko0A-3a69A:
12.56
3ko0B-3a69A:
12.56
3ko0I-3a69A:
12.56
3ko0J-3a69A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3a69 FLAGELLAR HOOK
PROTEIN FLGE
(Salmonella
enterica) 		4 / 8 ALA A 342
ILE A  76
THR A 116
VAL A  85
 None
 0.73A 4r20A-3a69A:
undetectable		 4r20A-3a69A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3a69 FLAGELLAR HOOK
PROTEIN FLGE
(Salmonella
enterica) 		3 / 3 ALA A  12
ASN A  15
LEU A  16
 None
 0.51A 5i1oA-3a69A:
undetectable		 5i1oA-3a69A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3a69 FLAGELLAR HOOK
PROTEIN FLGE
(Salmonella
enterica) 		3 / 3 SER A 152
ALA A 151
THR A 148
 None
 0.73A 5n0xB-3a69A:
undetectable		 5n0xB-3a69A:
22.15