SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 LEU A 193
THR A 150
VAL A 153
ALA A 226
 None
 0.90A 1fiqC-3a6pA:
undetectable		 1fiqC-3a6pA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 LEU A 539
VAL A 556
VAL A 619
LEU A 577
LEU A 626
 None
 1.23A 1mx1E-3a6pA:
undetectable		 1mx1E-3a6pA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 SER A 756
THR A 754
GLU A 742
LYS A 745
 None
 1.22A 1mxgA-3a6pA:
undetectable		 1mxgA-3a6pA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 10 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 0.96A 1pxxA-3a6pA:
undetectable		 1pxxA-3a6pA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 0.96A 1pxxC-3a6pA:
undetectable		 1pxxC-3a6pA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 3a6p EXPORTIN-5
(Homo
sapiens) 		3 / 3 ARG A 762
TYR A 662
LYS A 666
 None
 0.83A 1uujB-3a6pA:
undetectable		 1uujB-3a6pA:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 LEU A 772
ASN A 775
LEU A 779
ALA A 778
SER A 875
 None
 1.28A 2aa5B-3a6pA:
undetectable		 2aa5B-3a6pA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 PHE A 895
LEU A 868
ILE A 915
PHE A 877
SER A 874
 None
 1.21A 2lbdA-3a6pA:
undetectable		 2lbdA-3a6pA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 6 TRP A 128
MET A 135
MET A  95
LEU A 139
 None
 1.24A 2oz7A-3a6pA:
undetectable		 2oz7A-3a6pA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 6 ARG A 126
GLU A 127
GLN A 130
PRO A 129
 None
 1.41A 2qqtA-3a6pA:
undetectable		 2qqtA-3a6pA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 11 ASP A 163
MET A 154
THR A 230
GLY A 233
LEU A 182
 None
 1.28A 2uvnB-3a6pA:
2.4		 2uvnB-3a6pA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 11 LEU A 553
LEU A 466
VAL A 538
LEU A 577
ILE A 514
 None
 1.22A 2uxoB-3a6pA:
2.7		 2uxoB-3a6pA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 GLN A 871
LEU A 770
LYS A 771
LEU A 777
 None
 0.90A 2xn3A-3a6pA:
undetectable
2xn3B-3a6pA:
undetectable		 2xn3A-3a6pA:
15.11
2xn3B-3a6pA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 3a6p EXPORTIN-5
(Homo
sapiens) 		3 / 3 SER A 276
ARG A 284
GLN A 332
 None
 0.98A 2xnrA-3a6pA:
undetectable		 2xnrA-3a6pA:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 6 ILE A 608
ARG A 602
THR A 641
LEU A 640
 None
C  E  61 ( 3.6A)
G  E  62 ( 3.2A)
None
 1.03A 3ag1N-3a6pA:
undetectable
3ag1W-3a6pA:
undetectable		 3ag1N-3a6pA:
18.17
3ag1W-3a6pA:
4.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 725
ILE A 728
PHE A 862
ALA A 876
PHE A 895
 None
 1.39A 3apwB-3a6pA:
undetectable		 3apwB-3a6pA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 LEU A 193
THR A 150
VAL A 153
ALA A 226
 None
 0.90A 3ax9A-3a6pA:
undetectable		 3ax9A-3a6pA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 3a6p EXPORTIN-5
(Homo
sapiens) 		3 / 3 GLU A 138
LEU A 139
ASP A 140
 None
 0.47A 3ko0A-3a6pA:
undetectable		 3ko0A-3a6pA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 11 LEU A 873
SER A 875
PHE A 877
ILE A 915
ASP A 774
 None
 1.38A 3ko0C-3a6pA:
undetectable
3ko0D-3a6pA:
undetectable
3ko0E-3a6pA:
0.0
3ko0F-3a6pA:
undetectable		 3ko0C-3a6pA:
6.52
3ko0D-3a6pA:
6.52
3ko0E-3a6pA:
6.52
3ko0F-3a6pA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 11 LEU A 873
SER A 875
PHE A 877
ILE A 915
ASP A 774
 None
 1.42A 3ko0O-3a6pA:
undetectable
3ko0P-3a6pA:
undetectable
3ko0Q-3a6pA:
0.6
3ko0R-3a6pA:
0.0		 3ko0O-3a6pA:
6.52
3ko0P-3a6pA:
6.52
3ko0Q-3a6pA:
6.52
3ko0R-3a6pA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 896
LEU A 899
LEU A 972
VAL A 912
LEU A 919
 None
 1.03A 3pghD-3a6pA:
undetectable		 3pghD-3a6pA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 TYR A 726
GLY A 730
SER A 727
ILE A 850
LEU A 654
 None
 1.20A 3q87B-3a6pA:
undetectable		 3q87B-3a6pA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 5 TYR A 922
THR A 921
PHE A 920
LEU A 927
 None
 0.80A 3qelC-3a6pA:
undetectable		 3qelC-3a6pA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 LEU A 193
THR A 150
VAL A 153
ALA A 226
 None
 0.87A 3uniB-3a6pA:
undetectable		 3uniB-3a6pA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 GLY A  67
ILE A 119
VAL A 120
ASN A 100
LEU A  52
 None
 1.12A 4a81A-3a6pA:
undetectable		 4a81A-3a6pA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 0.96A 4coxC-3a6pA:
undetectable		 4coxC-3a6pA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 SER A 656
PHE A 659
ASP A 624
TYR A 627
 None
 0.95A 4drjB-3a6pA:
4.2		 4drjB-3a6pA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 7 VAL A 275
PHE A 356
GLY A 330
THR A 374
 None
 0.92A 4ejjB-3a6pA:
undetectable		 4ejjB-3a6pA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 ALA A 302
ILE A 273
LEU A 228
LEU A 231
GLY A 233
 None
 1.04A 4l9qB-3a6pA:
2.9		 4l9qB-3a6pA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 ALA A 226
LEU A 136
LEU A 139
ALA A 227
TYR A 234
 None
 0.86A 4lg1A-3a6pA:
undetectable		 4lg1A-3a6pA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 ALA A 226
LEU A 136
LEU A 139
ALA A 227
TYR A 234
 None
 0.86A 4lg1B-3a6pA:
undetectable		 4lg1B-3a6pA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 ALA A 226
LEU A 136
LEU A 139
ALA A 227
TYR A 234
 None
 0.88A 4lg1C-3a6pA:
undetectable		 4lg1C-3a6pA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 8 PHE A 426
ASP A 425
SER A 364
SER A 369
 None
 1.17A 4lv9A-3a6pA:
undetectable
4lv9B-3a6pA:
undetectable		 4lv9A-3a6pA:
18.11
4lv9B-3a6pA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 7 PHE A 426
ASP A 425
SER A 364
SER A 369
 None
 1.21A 4lv9A-3a6pA:
undetectable
4lv9B-3a6pA:
undetectable		 4lv9A-3a6pA:
18.11
4lv9B-3a6pA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 4 LEU A 559
SER A 557
LEU A 539
LEU A 466
 None
 1.06A 4n09A-3a6pA:
undetectable		 4n09A-3a6pA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 7 MET A 964
TYR A 886
GLU A 809
ARG A 887
 None
 1.33A 4r87J-3a6pA:
undetectable
4r87L-3a6pA:
undetectable		 4r87J-3a6pA:
9.14
4r87L-3a6pA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 0.97A 4rrwD-3a6pA:
undetectable		 4rrwD-3a6pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 0.97A 4rrzD-3a6pA:
undetectable		 4rrzD-3a6pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 9 VAL A 325
LEU A 272
GLY A 266
ALA A 267
LEU A 258
 None
 1.00A 4rs0A-3a6pA:
undetectable		 4rs0A-3a6pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3a6p EXPORTIN-5
(Homo
sapiens) 		3 / 3 MET A  82
GLU A  86
LEU A  90
 None
 0.39A 4v2oB-3a6pA:
3.8		 4v2oB-3a6pA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 5 ILE A 119
VAL A  94
ILE A  98
VAL A 120
 None
 0.62A 4xdtA-3a6pA:
undetectable		 4xdtA-3a6pA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 9 LEU A1028
VAL A1024
GLY A 917
VAL A 900
VAL A 912
 None
 1.41A 5cp4A-3a6pA:
undetectable		 5cp4A-3a6pA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 896
LEU A 899
LEU A 972
VAL A 912
LEU A 919
 None
 1.10A 5ikrB-3a6pA:
undetectable		 5ikrB-3a6pA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 5 ILE A 273
LEU A 251
HIS A 242
VAL A 238
 None
 1.23A 5jmnB-3a6pA:
undetectable		 5jmnB-3a6pA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3a6p EXPORTIN-5
(Homo
sapiens) 		3 / 3 HIS A  73
LYS A  76
PHE A  77
 None
 1.17A 5klaA-3a6pA:
4.1		 5klaA-3a6pA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 LEU A 851
ILE A 883
LEU A 923
PHE A 877
LEU A 965
 None
 1.13A 5tiwA-3a6pA:
undetectable		 5tiwA-3a6pA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3a6p EXPORTIN-5
(Homo
sapiens) 		5 / 12 VAL A 732
LEU A 777
LEU A 851
ALA A 854
SER A 857
 None
 0.92A 6b0iB-3a6pA:
undetectable		 6b0iB-3a6pA:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 7 PHE A 359
ARG A 368
LEU A 367
GLN A 372
 None
 1.26A 6b89A-3a6pA:
undetectable		 6b89A-3a6pA:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3a6p EXPORTIN-5
(Homo
sapiens) 		4 / 5 TYR A 844
ARG A 887
MET A 891
LEU A 892
 None
 1.03A 6nknW-3a6pA:
undetectable		 6nknW-3a6pA:
4.28