SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LEU A 184
ALA A 143
LEU A 123
SER A 110
LEU A 111
 None
 1.02A 2c12C-3a71A:
undetectable		 2c12C-3a71A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 11 LEU A 184
ALA A 143
LEU A 123
SER A 110
LEU A 111
 None
 1.02A 2c12F-3a71A:
undetectable		 2c12F-3a71A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 ARG A 164
VAL A 172
THR A 137
 None
 0.84A 2nnkA-3a71A:
undetectable		 2nnkA-3a71A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		4 / 7 ASP A 190
TYR A 188
PRO A 171
THR A 137
 MPD  A 404 (-3.1A)
None
None
None
 1.48A 2q6kA-3a71A:
undetectable		 2q6kA-3a71A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		4 / 7 SER A 283
LEU A 260
LEU A 279
THR A 285
 None
 1.03A 3cfqA-3a71A:
undetectable
3cfqB-3a71A:
undetectable		 3cfqA-3a71A:
15.17
3cfqB-3a71A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 HIS A 335
THR A 311
GLY A 358
GLY A 336
LEU A 360
 None
None
None
None
MPD  A 402 ( 4.7A)
 1.19A 3fzgA-3a71A:
undetectable		 3fzgA-3a71A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 THR A 288
GLN A 312
LEU A 360
GLY A 310
HIS A 335
 None
None
MPD  A 402 ( 4.7A)
None
None
 1.35A 3g1uB-3a71A:
undetectable		 3g1uB-3a71A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		4 / 6 ARG A 227
SER A 289
TYR A 337
PRO A 165
 None
None
MPD  A 402 (-4.5A)
MPD  A 402 (-4.3A)
 1.34A 3jqaA-3a71A:
undetectable		 3jqaA-3a71A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		4 / 6 ARG A 227
SER A 289
TYR A 337
PRO A 165
 None
None
MPD  A 402 (-4.5A)
MPD  A 402 (-4.3A)
 1.32A 3jqaB-3a71A:
undetectable		 3jqaB-3a71A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 ARG A 164
VAL A 172
THR A 137
 None
 0.85A 3k4vA-3a71A:
undetectable		 3k4vA-3a71A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 ARG A 164
VAL A 172
THR A 137
 None
 0.83A 3nduD-3a71A:
undetectable		 3nduD-3a71A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OPE_A_SAMA7_0
(PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LYS A 183
GLY A 182
TYR A 109
HIS A 203
TYR A 187
 None
 1.43A 3opeA-3a71A:
undetectable		 3opeA-3a71A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 TYR A 188
ASP A 218
ASP A 267
 None
 0.68A 3ou6B-3a71A:
undetectable		 3ou6B-3a71A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 ARG A 164
VAL A 172
THR A 137
 None
 0.82A 3tl9A-3a71A:
undetectable		 3tl9A-3a71A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 ILE A  90
ASP A 146
LEU A 125
LEU A 108
ILE A  77
 None
 1.04A 4m2xE-3a71A:
undetectable		 4m2xE-3a71A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 11 LEU A 134
GLY A 101
LEU A 102
SER A 128
PHE A  75
 None
 1.04A 4wnuA-3a71A:
undetectable		 4wnuA-3a71A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 11 LEU A 134
GLY A 101
LEU A 102
SER A 128
PHE A  75
 None
 1.18A 4wnuC-3a71A:
undetectable		 4wnuC-3a71A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNP_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LYS A 183
GLY A 182
TYR A 109
HIS A 203
TYR A 187
 None
 1.49A 4ynpA-3a71A:
undetectable		 4ynpA-3a71A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPU_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LYS A 183
GLY A 182
TYR A 109
HIS A 203
TYR A 187
 None
 1.50A 4ypuA-3a71A:
undetectable		 4ypuA-3a71A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 GLY A 101
ARG A 103
TYR A 104
TYR A 142
LEU A 125
 None
None
ACT  A 401 (-3.6A)
None
None
 1.34A 5czyA-3a71A:
undetectable		 5czyA-3a71A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		4 / 7 GLY A 182
GLY A 116
SER A 117
PHE A 118
 None
 0.83A 5izfA-3a71A:
undetectable		 5izfA-3a71A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 11 VAL A 371
SER A 370
GLU A 333
PRO A  26
LEU A 344
 None
 1.49A 5jh7B-3a71A:
undetectable		 5jh7B-3a71A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 11 VAL A 371
SER A 370
GLU A 333
PRO A  26
LEU A 344
 None
 1.44A 5jh7D-3a71A:
undetectable		 5jh7D-3a71A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LEU A 108
ALA A 340
GLY A 127
ALA A 126
LEU A 141
 None
 1.08A 5jw1B-3a71A:
undetectable		 5jw1B-3a71A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 LEU A 108
ALA A 340
GLY A 127
ALA A 126
LEU A 141
 None
 0.98A 5kirA-3a71A:
undetectable		 5kirA-3a71A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.65A 5qglA-3a71A:
undetectable		 5qglA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.68A 5qguA-3a71A:
undetectable		 5qguA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.71A 5qgvA-3a71A:
undetectable		 5qgvA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.71A 5qgwA-3a71A:
undetectable		 5qgwA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.71A 5qgxA-3a71A:
undetectable		 5qgxA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.71A 5qh1A-3a71A:
undetectable		 5qh1A-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.71A 5qh4A-3a71A:
undetectable		 5qh4A-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.68A 5qhaA-3a71A:
undetectable		 5qhaA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.68A 5qhcA-3a71A:
undetectable		 5qhcA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		3 / 3 VAL A 371
VAL A 353
GLN A  53
 None
 0.69A 5qheA-3a71A:
undetectable		 5qheA-3a71A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSF_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 3a71 EXO-ARABINANASE
(Penicillium
chrysogenum) 		5 / 12 GLY A 229
SER A 249
TYR A 256
PHE A 251
ARG A 263
 None
 1.41A 5vsfB-3a71A:
undetectable		 5vsfB-3a71A:
20.81