SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 ASP A   3
ARG A  10
ARG A   6
 None
 0.86A 2j9dA-3a76A:
undetectable
2j9dC-3a76A:
undetectable		 2j9dA-3a76A:
20.81
2j9dC-3a76A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 GLU A  45
GLY A  48
THR A  49
 None
 0.48A 3iazA-3a76A:
undetectable		 3iazA-3a76A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		4 / 5 PHE A 113
ALA A 131
THR A 133
LEU A  64
 GOL  A 502 (-4.9A)
GOL  A 502 (-3.0A)
SPD  A 300 (-4.0A)
SPD  A 300 ( 4.9A)
 1.05A 3t3zC-3a76A:
undetectable		 3t3zC-3a76A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		4 / 6 ILE A  72
VAL A  24
LEU A  32
ILE A  22
 None
 0.79A 4asdA-3a76A:
undetectable		 4asdA-3a76A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		4 / 5 LEU A  59
ALA A 131
THR A 133
ILE A 109
 None
GOL  A 502 (-3.0A)
SPD  A 300 (-4.0A)
None
 0.97A 4xe3A-3a76A:
undetectable		 4xe3A-3a76A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A  21
THR A 133
ASN A 134
 None
SPD  A 300 (-4.0A)
None
 0.74A 6baaE-3a76A:
undetectable		 6baaE-3a76A:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A  21
THR A 133
ASN A 134
 None
SPD  A 300 (-4.0A)
None
 0.74A 6baaF-3a76A:
undetectable		 6baaF-3a76A:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A  21
THR A 133
ASN A 134
 None
SPD  A 300 (-4.0A)
None
 0.74A 6baaG-3a76A:
undetectable		 6baaG-3a76A:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A  21
THR A 133
ASN A 134
 None
SPD  A 300 (-4.0A)
None
 0.74A 6baaH-3a76A:
undetectable		 6baaH-3a76A:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 3a76 GAMMA-HEXACHLOROCYCL
OHEXANE
DEHYDROCHLORINASE
(Sphingomonas
paucimobilis) 		3 / 3 GLY A  92
ASP A 115
ILE A  13
 None
 0.53A 6dgxB-3a76A:
undetectable		 6dgxB-3a76A:
18.63