SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 PHE B 158
ALA B 155
LEU B 153
VAL B 138
 None
 0.77A 1hk2A-3a79B:
undetectable		 1hk2A-3a79B:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 LEU B 105
PHE B  96
LEU B 123
MET B 120
ILE B  88
 None
 1.38A 1hrkB-3a79B:
undetectable		 1hrkB-3a79B:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 LEU B 153
SER B 154
ASP B 177
PHE B 150
 None
 1.19A 1ismB-3a79B:
2.2		 1ismB-3a79B:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 LEU B 251
THR B 302
MET B 331
GLN B 271
 None
 1.26A 1kglA-3a79B:
undetectable		 1kglA-3a79B:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 VAL B 211
LEU B 178
SER B 154
LEU B 153
GLU B 189
 None
 1.16A 1mmkA-3a79B:
undetectable		 1mmkA-3a79B:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 11 LEU B  78
ASN B 110
ILE B  88
LEU B  67
PHE B  96
 None
 1.31A 1tw4A-3a79B:
undetectable		 1tw4A-3a79B:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 4 ASP B 127
LEU B 176
LEU B 153
LEU B 175
 None
 1.42A 1u18A-3a79B:
undetectable		 1u18A-3a79B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.06A 1v54A-3a79B:
undetectable
1v54J-3a79B:
undetectable		 1v54A-3a79B:
20.37
1v54J-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 4 LEU B 136
LEU B 128
SER B 129
LEU B 175
 None
 0.97A 1ya3A-3a79B:
undetectable		 1ya3A-3a79B:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 LEU B  67
PRO B  47
VAL B  46
ILE B  64
 None
 0.94A 2aoiB-3a79B:
undetectable		 2aoiB-3a79B:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 SER B  58
ASP B  37
SER B  34
LEU B  50
 None
 1.09A 2cdqB-3a79B:
undetectable		 2cdqB-3a79B:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 SER B 436
SER B 437
SER B 411
ASN B 434
 NDG  B 971 (-3.6A)
NAG  B 972 ( 4.2A)
NDG  B 971 (-2.7A)
NDG  B 971 (-2.1A)
 1.02A 2cmlA-3a79B:
undetectable		 2cmlA-3a79B:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 8 SER B 436
SER B 437
SER B 411
ASN B 434
 NDG  B 971 (-3.6A)
NAG  B 972 ( 4.2A)
NDG  B 971 (-2.7A)
NDG  B 971 (-2.1A)
 0.94A 2cmlB-3a79B:
undetectable		 2cmlB-3a79B:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 8 SER B 436
SER B 437
SER B 411
ASN B 434
 NDG  B 971 (-3.6A)
NAG  B 972 ( 4.2A)
NDG  B 971 (-2.7A)
NDG  B 971 (-2.1A)
 0.98A 2cmlC-3a79B:
undetectable		 2cmlC-3a79B:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 8 SER B 436
SER B 437
SER B 411
ASN B 434
 NDG  B 971 (-3.6A)
NAG  B 972 ( 4.2A)
NDG  B 971 (-2.7A)
NDG  B 971 (-2.1A)
 1.07A 2cmlD-3a79B:
undetectable		 2cmlD-3a79B:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.08A 2dyrA-3a79B:
undetectable
2dyrJ-3a79B:
undetectable		 2dyrA-3a79B:
20.37
2dyrJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.06A 2dysA-3a79B:
undetectable
2dysJ-3a79B:
undetectable		 2dysA-3a79B:
20.37
2dysJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 0.99A 2dysN-3a79B:
undetectable
2dysW-3a79B:
undetectable		 2dysN-3a79B:
20.37
2dysW-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 PHE B 328
ILE B 283
SER B 266
ILE B 259
ILE B 288
 None
 1.32A 2efjA-3a79B:
2.3		 2efjA-3a79B:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.07A 2eijA-3a79B:
undetectable
2eijJ-3a79B:
undetectable		 2eijA-3a79B:
20.37
2eijJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.02A 2eilA-3a79B:
undetectable
2eilJ-3a79B:
undetectable		 2eilA-3a79B:
20.37
2eilJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 LEU B 225
LEU B 201
PHE B 203
LEU B 238
 None
 0.66A 2vq5B-3a79B:
undetectable		 2vq5B-3a79B:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 PHE B 493
LEU B 485
VAL B 480
VAL B 469
 None
 1.05A 2zaxA-3a79B:
undetectable		 2zaxA-3a79B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 PHE B 493
LEU B 485
VAL B 480
VAL B 469
 None
 0.98A 2zuhA-3a79B:
undetectable		 2zuhA-3a79B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 PHE B 493
LEU B 485
VAL B 480
VAL B 469
 None
 1.04A 2zwtA-3a79B:
undetectable		 2zwtA-3a79B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.05A 2zxwA-3a79B:
undetectable
2zxwJ-3a79B:
undetectable		 2zxwA-3a79B:
20.37
2zxwJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.03A 3asnA-3a79B:
undetectable
3asnJ-3a79B:
undetectable		 3asnA-3a79B:
20.37
3asnJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B 433
ARG B 446
THR B 441
LEU B 440
 None
 1.05A 3asoA-3a79B:
undetectable
3asoJ-3a79B:
undetectable		 3asoA-3a79B:
20.37
3asoJ-3a79B:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 LEU B 178
LEU B 245
LEU B 191
HIS B 200
LEU B 225
 None
 1.17A 3erdA-3a79B:
undetectable		 3erdA-3a79B:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 VAL B 278
SER B 266
ILE B 333
ILE B 338
VAL B 312
 None
 1.35A 3g8iA-3a79B:
undetectable		 3g8iA-3a79B:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 10 LEU B 281
SER B 306
ILE B 283
SER B 339
SER B 337
 None
None
None
NAG  B 951 (-3.3A)
NAG  B 951 ( 4.9A)
 1.38A 3ijxB-3a79B:
undetectable
3ijxD-3a79B:
undetectable		 3ijxB-3a79B:
17.45
3ijxD-3a79B:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 10 LEU B 281
SER B 306
ILE B 283
SER B 339
SER B 337
 None
None
None
NAG  B 951 (-3.3A)
NAG  B 951 ( 4.9A)
 1.37A 3ik6B-3a79B:
undetectable
3ik6E-3a79B:
undetectable		 3ik6B-3a79B:
17.45
3ik6E-3a79B:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 10 LEU B 281
SER B 306
ILE B 283
SER B 339
SER B 337
 None
None
None
NAG  B 951 (-3.3A)
NAG  B 951 ( 4.9A)
 1.32A 3iluB-3a79B:
undetectable
3iluE-3a79B:
undetectable		 3iluB-3a79B:
17.45
3iluE-3a79B:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		3 / 3 SER B 180
ASP B 177
ASP B 134
 None
 0.79A 3iv6A-3a79B:
undetectable		 3iv6A-3a79B:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		3 / 3 SER B 180
ASP B 177
ASP B 134
 None
 0.81A 3iv6C-3a79B:
undetectable		 3iv6C-3a79B:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 11 LEU B 269
LEU B 281
VAL B 254
ILE B 259
THR B 246
 None
 1.23A 3jw5A-3a79B:
undetectable		 3jw5A-3a79B:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 10 LEU B 269
LEU B 281
VAL B 254
ILE B 259
THR B 246
 None
 1.17A 3jw5B-3a79B:
undetectable		 3jw5B-3a79B:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 7 PHE B 393
PHE B 392
LEU B 455
LEU B 435
 None
 0.69A 4ejgC-3a79B:
undetectable		 4ejgC-3a79B:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 PHE B 493
LEU B 485
VAL B 480
VAL B 469
 None
 1.10A 4ek1A-3a79B:
undetectable		 4ek1A-3a79B:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 MET B 402
LEU B 405
PRO B 349
SER B 353
 None
 1.03A 4kmmB-3a79B:
undetectable		 4kmmB-3a79B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 ASN B 413
LEU B 415
SER B 437
ASN B 483
 None
None
NAG  B 972 ( 4.2A)
None
 1.12A 4n09C-3a79B:
undetectable		 4n09C-3a79B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 ASN B 413
LEU B 415
SER B 437
LEU B 457
 None
None
NAG  B 972 ( 4.2A)
None
 1.31A 4n09C-3a79B:
undetectable		 4n09C-3a79B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		6 / 10 LEU B 201
LEU B 153
LEU B 163
ILE B 193
LEU B 191
LEU B 223
 None
 1.14A 4odoA-3a79B:
undetectable		 4odoA-3a79B:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		6 / 10 LEU B 201
LEU B 153
LEU B 163
ILE B 193
LEU B 191
LEU B 223
 None
 1.17A 4odoB-3a79B:
undetectable		 4odoB-3a79B:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 6 LEU B  75
ASN B  99
LEU B  59
VAL B 107
 None
 0.90A 4okbA-3a79B:
undetectable		 4okbA-3a79B:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 12 VAL B 530
ILE B 523
ARG B 552
TRP B 509
VAL B 480
 None
 1.44A 4rujA-3a79B:
undetectable		 4rujA-3a79B:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		3 / 3 ASN B 359
SER B 339
ARG B 386
 NAG  B 951 (-1.7A)
NAG  B 951 (-3.3A)
NAG  B 952 (-3.1A)
 0.86A 5b2qA-3a79B:
undetectable		 5b2qA-3a79B:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 8 LEU B 178
PHE B 209
ILE B 228
PHE B 241
LEU B 199
 None
 1.39A 5eseA-3a79B:
undetectable		 5eseA-3a79B:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 4 ASN B 387
LEU B 389
SER B 411
LEU B 408
 None
None
NDG  B 971 (-2.7A)
None
 1.08A 5kb5A-3a79B:
undetectable		 5kb5A-3a79B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 4 ASN B 413
LEU B 415
SER B 437
LEU B 457
 None
None
NAG  B 972 ( 4.2A)
None
 1.34A 5kb5A-3a79B:
undetectable		 5kb5A-3a79B:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 ASN B 363
ASN B 359
ASP B 409
ASN B 413
 None
NAG  B 951 (-1.7A)
NDG  B 971 ( 4.1A)
None
 1.43A 5vooE-3a79B:
2.1		 5vooE-3a79B:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		4 / 5 TRP B 426
LEU B 448
VAL B 444
LEU B 435
 None
 1.05A 5xooB-3a79B:
undetectable		 5xooB-3a79B:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B
(Eptatretus
burgeri;
Mus
musculus) 		5 / 9 LEU B 496
VAL B 469
SER B 487
LEU B 485
ILE B 465
 None
 1.27A 6fdyU-3a79B:
undetectable		 6fdyU-3a79B:
17.79