SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		4 / 7 GLY A  27
ALA A  60
ILE A 101
SER A  67
 None
 0.80A 1gtnA-3a7lA:
undetectable
1gtnK-3a7lA:
undetectable		 1gtnA-3a7lA:
18.94
1gtnK-3a7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		4 / 8 SER A  67
GLY A  27
ALA A  60
ILE A 101
 None
 0.83A 1gtnE-3a7lA:
undetectable
1gtnF-3a7lA:
undetectable		 1gtnE-3a7lA:
18.94
1gtnF-3a7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		5 / 9 VAL A  91
GLY A  27
ALA A  60
ILE A 101
SER A  67
 None
 0.99A 1gtnL-3a7lA:
undetectable
1gtnM-3a7lA:
undetectable		 1gtnL-3a7lA:
18.94
1gtnM-3a7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		4 / 8 GLY A  27
ALA A  60
ILE A 101
SER A  67
 None
 0.77A 1gtnP-3a7lA:
undetectable
1gtnQ-3a7lA:
undetectable		 1gtnP-3a7lA:
18.94
1gtnQ-3a7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		4 / 8 GLY A  75
VAL A  51
SER A 107
ILE A 104
 None
 0.81A 1pk7B-3a7lA:
undetectable		 1pk7B-3a7lA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3a7l GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Escherichia
coli) 		5 / 11 ILE A 104
GLU A  14
LEU A  16
GLY A  75
GLU A 111
 None
 1.15A 2fn1A-3a7lA:
undetectable		 2fn1A-3a7lA:
17.42