SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		5 / 12 ILE A 186
VAL A 166
VAL A 203
ILE A 204
ILE A 208
 None
 0.94A 1epbA-3a7sA:
undetectable		 1epbA-3a7sA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		5 / 10 LEU A 178
ALA A  80
LEU A 130
LEU A  98
ILE A  93
 None
 1.04A 2w9hA-3a7sA:
undetectable		 2w9hA-3a7sA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		5 / 12 ARG A  73
LEU A  74
ARG A 182
ALA A  65
GLU A 177
 None
 1.46A 3k39C-3a7sA:
undetectable		 3k39C-3a7sA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		5 / 12 ARG A  73
LEU A  74
ARG A 182
ALA A  65
GLU A 177
 None
 1.47A 3k39I-3a7sA:
undetectable		 3k39I-3a7sA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		5 / 12 ARG A  73
LEU A  74
ARG A 182
ALA A  65
GLU A 177
 None
 1.45A 3k39O-3a7sA:
undetectable		 3k39O-3a7sA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		4 / 6 LEU A  97
SER A  95
ILE A 223
PHE A  54
 None
 0.95A 3ko0B-3a7sA:
undetectable		 3ko0B-3a7sA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		4 / 7 GLU A 177
TYR A 211
PHE A  54
TYR A 168
 None
 1.32A 3ku9B-3a7sA:
undetectable		 3ku9B-3a7sA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		4 / 6 PHE A  56
ILE A 216
PHE A 218
PHE A  54
 None
 0.98A 4fgkA-3a7sA:
undetectable		 4fgkA-3a7sA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5
(Homo
sapiens) 		4 / 5 LEU A  55
ALA A  92
VAL A  32
ILE A 223
 None
 0.82A 4xe3A-3a7sA:
undetectable		 4xe3A-3a7sA:
21.71