SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		3 / 3 SER A 715
HIS A 734
ASP A 594
 None
 0.74A 2oxtA-3a8pA:
undetectable		 2oxtA-3a8pA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		3 / 3 ARG A 691
SER A 591
TYR A 695
 None
 1.02A 2q2hA-3a8pA:
undetectable
2q2hB-3a8pA:
undetectable		 2q2hA-3a8pA:
17.83
2q2hB-3a8pA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		4 / 5 GLN A 674
ALA A 655
GLN A 658
ILE A 671
 None
 1.33A 2z0aA-3a8pA:
3.4		 2z0aA-3a8pA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		4 / 6 SER A 589
ILE A 613
CYH A 617
PHE A 621
 None
 1.00A 3ko0B-3a8pA:
undetectable		 3ko0B-3a8pA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		4 / 5 HIS A 614
CYH A 694
ILE A 572
LEU A 704
 None
 1.37A 3qpkA-3a8pA:
undetectable		 3qpkA-3a8pA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		5 / 12 GLY A 542
CYH A 543
HIS A 614
TYR A 695
LEU A 588
 None
 1.45A 4emaA-3a8pA:
1.3		 4emaA-3a8pA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		5 / 12 CYH A 694
TYR A 695
LEU A 588
VAL A 610
ILE A 613
 None
 1.40A 4k36B-3a8pA:
undetectable		 4k36B-3a8pA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		5 / 11 CYH A 694
TYR A 695
LEU A 588
VAL A 610
ILE A 613
 None
 1.38A 4k37A-3a8pA:
undetectable		 4k37A-3a8pA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		4 / 4 GLY A 593
VAL A 595
PHE A 690
ILE A 572
 None
 1.17A 4xv2B-3a8pA:
undetectable		 4xv2B-3a8pA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		5 / 12 LEU A 566
LEU A 540
VAL A 573
LEU A 606
PHE A 586
 None
 1.13A 4y0qA-3a8pA:
undetectable		 4y0qA-3a8pA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2
(Mus
musculus) 		5 / 10 LEU A 540
LEU A 545
SER A 589
LEU A 588
LEU A 511
 None
 1.20A 4yiaA-3a8pA:
undetectable		 4yiaA-3a8pA:
22.81