SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		5 / 12 GLY A 183
MET A 240
MET A 188
ILE A 186
LEU A 225
 None
 1.31A 1lhuA-3a8rA:
undetectable		 1lhuA-3a8rA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		4 / 7 PHE A 151
ALA A 264
PHE A 194
SER A 191
 None
 1.16A 1lqtA-3a8rA:
undetectable		 1lqtA-3a8rA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		4 / 7 PHE A 151
ALA A 264
PHE A 194
SER A 191
 None
 1.18A 1lquA-3a8rA:
undetectable		 1lquA-3a8rA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		3 / 3 VAL A 196
ASP A 200
GLU A 193
 None
 0.75A 2qeuA-3a8rA:
undetectable		 2qeuA-3a8rA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		3 / 3 VAL A 196
ASP A 200
GLU A 193
 None
 0.73A 2qeuC-3a8rA:
undetectable		 2qeuC-3a8rA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		4 / 5 VAL A 176
VAL A 173
GLN A 170
PHE A 182
 None
 1.30A 3bjwH-3a8rA:
undetectable		 3bjwH-3a8rA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		4 / 5 VAL A 176
VAL A 173
GLN A 170
PHE A 182
 None
 1.26A 3bjwB-3a8rA:
undetectable		 3bjwB-3a8rA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		5 / 12 SER A 201
LEU A 202
PHE A 182
MET A 188
GLY A 157
 None
 1.01A 4j7xA-3a8rA:
undetectable		 4j7xA-3a8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		5 / 12 SER A 201
LEU A 202
PHE A 182
MET A 188
GLY A 157
 None
 1.06A 4j7xB-3a8rA:
undetectable		 4j7xB-3a8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		5 / 12 SER A 201
LEU A 202
PHE A 182
MET A 188
GLY A 157
 None
 1.03A 4j7xF-3a8rA:
undetectable		 4j7xF-3a8rA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		3 / 3 ASP A 231
GLY A 229
ASP A 227
 None
 0.64A 4xdtA-3a8rA:
undetectable		 4xdtA-3a8rA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		5 / 11 PHE A 199
ALA A 203
GLY A 207
LYS A 210
LEU A 177
 None
 1.14A 4zmeA-3a8rA:
undetectable		 4zmeA-3a8rA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		3 / 3 ARG A 204
ARG A 235
ARG A 248
 None
 0.94A 5vcgA-3a8rA:
undetectable		 5vcgA-3a8rA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3a8r PUTATIVE
UNCHARACTERIZED
PROTEIN
(Oryza
sativa) 		4 / 8 GLU A 256
PHE A 199
PHE A 182
LEU A 213
 None
 0.90A 5y2tB-3a8rA:
undetectable		 5y2tB-3a8rA:
undetectable