SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 6 TRP A 127
LEU A 144
LEU A 136
PRO A 137
 None
 1.07A 1hz4A-3a98A:
1.7		 1hz4A-3a98A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 ASP A 162
LEU A 163
THR A 149
ILE A 152
MET A 120
 None
 1.50A 1xoqA-3a98A:
undetectable		 1xoqA-3a98A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 6 ASP A 162
THR A  94
GLU A  97
GLU A  90
 None
 1.38A 2dttB-3a98A:
undetectable
2dttC-3a98A:
undetectable		 2dttB-3a98A:
21.93
2dttC-3a98A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU B 699
LEU B 696
LEU B 690
MET A 125
 None
 0.85A 2oaxF-3a98B:
undetectable		 2oaxF-3a98B:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 LEU A  87
GLU A  90
ASN A 156
LEU A  95
LEU A 124
 None
 1.30A 3g1uA-3a98A:
undetectable		 3g1uA-3a98A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_B_ROFB902_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 ASP A 162
LEU A 163
THR A 149
ILE A 152
MET A 120
 None
 1.47A 3g4lB-3a98A:
undetectable		 3g4lB-3a98A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 ASP A 162
LEU A 163
THR A 149
ILE A 152
MET A 120
 None
 1.50A 3g4lC-3a98A:
undetectable		 3g4lC-3a98A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 6 SER A 109
PHE A 114
ASP B 685
TYR A 106
 None
 1.45A 3jqaA-3a98A:
undetectable		 3jqaA-3a98A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 6 SER A 109
PHE A 114
ASP B 685
TYR A 106
 None
 1.44A 3jqaB-3a98A:
undetectable		 3jqaB-3a98A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 6 SER A 109
PHE A 114
ASP B 685
TYR A 106
 None
 1.43A 3jqaC-3a98A:
undetectable		 3jqaC-3a98A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 6 SER A 109
PHE A 114
ASP B 685
TYR A 106
 None
 1.44A 3jqaD-3a98A:
undetectable		 3jqaD-3a98A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3a98 ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL B 610
LEU B 579
CYH B 577
THR B 560
PHE B 562
 None
 1.35A 3mnoA-3a98B:
undetectable		 3mnoA-3a98B:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3a98 ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL B 610
LEU B 579
CYH B 577
THR B 560
PHE B 562
 None
 1.39A 3mnpA-3a98B:
undetectable		 3mnpA-3a98B:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3a98 ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU B 698
LEU B 701
PRO B 707
ILE B 706
 None
 0.78A 3s56B-3a98B:
undetectable		 3s56B-3a98B:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3a98 ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		4 / 4 ASN B 653
LEU B 638
PHE B 562
TYR B 662
 None
 1.50A 4u14A-3a98B:
0.0		 4u14A-3a98B:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		5 / 10 GLY A  32
ASN A  18
ILE B 704
PRO B 707
LEU B 701
 None
 0.82A 4xj7A-3a98A:
undetectable
4xj7B-3a98A:
undetectable		 4xj7A-3a98A:
21.43
4xj7B-3a98A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1
(Homo
sapiens) 		5 / 10 LEU B 701
GLY A  32
ASN A  18
ILE B 704
PRO B 707
 None
 0.88A 4xj7C-3a98B:
undetectable
4xj7D-3a98B:
undetectable		 4xj7C-3a98B:
21.59
4xj7D-3a98B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 10 ALA A  15
LEU A  49
ASP A  33
VAL A  35
GLY A  47
 None
 1.43A 5zbdB-3a98A:
undetectable		 5zbdB-3a98A:
19.80