SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3a9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 7 VAL A  88
LEU A  29
VAL A  28
LEU A  41
 None
 0.80A 1cqpA-3a9vA:
2.7
1cqpB-3a9vA:
2.8		 1cqpA-3a9vA:
15.99
1cqpB-3a9vA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 ALA A  90
PHE A 159
LEU A  41
LEU A 243
LEU A 238
 None
 1.21A 1dtlA-3a9vA:
undetectable		 1dtlA-3a9vA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 7 LEU A 299
ALA A 324
PHE A 321
VAL A 317
 None
 0.90A 1epbA-3a9vA:
undetectable		 1epbA-3a9vA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 ASP A 423
ASP A 425
LYS A 353
 None
 1.16A 1lqtB-3a9vA:
undetectable		 1lqtB-3a9vA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 ASP A 423
ASP A 425
LYS A 353
 None
 1.13A 1lquB-3a9vA:
undetectable		 1lquB-3a9vA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 ASN A  46
TYR A  50
SER A  84
 None
 0.93A 2gvcB-3a9vA:
undetectable		 2gvcB-3a9vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 ASN A  46
TYR A  50
SER A  84
 None
 0.94A 2gvcE-3a9vA:
undetectable		 2gvcE-3a9vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 LEU A 309
LEU A 326
ALA A 324
LEU A 230
ILE A 226
 None
 0.96A 2h42C-3a9vA:
undetectable		 2h42C-3a9vA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 ALA A  63
SER A  64
ALA A 165
ALA A  94
TYR A  50
 None
 1.06A 2igtA-3a9vA:
undetectable		 2igtA-3a9vA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 ALA A  63
SER A  64
ALA A 165
ALA A  94
TYR A  50
 None
 1.04A 2igtB-3a9vA:
undetectable		 2igtB-3a9vA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 ALA A  63
SER A  64
ALA A 165
ALA A  94
TYR A  50
 None
 1.08A 2igtC-3a9vA:
undetectable		 2igtC-3a9vA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 6 LEU A 198
ILE A 235
ILE A 254
LEU A 246
 None
 0.98A 2xkwB-3a9vA:
undetectable		 2xkwB-3a9vA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 PHE A 107
ASN A 105
PHE A 442
 None
 1.09A 2zbuD-3a9vA:
undetectable		 2zbuD-3a9vA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 PHE A 107
ASN A 105
PHE A 503
 None
 1.01A 2zbuD-3a9vA:
undetectable		 2zbuD-3a9vA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 10 ILE A 175
GLY A  98
ALA A  99
HIS A  25
HIS A  96
 None
 1.19A 3boyA-3a9vA:
undetectable
3boyC-3a9vA:
undetectable		 3boyA-3a9vA:
15.46
3boyC-3a9vA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 10 HIS A  96
ILE A 175
GLY A  98
ALA A  99
HIS A  25
 None
 1.20A 3boyA-3a9vA:
undetectable
3boyB-3a9vA:
undetectable		 3boyA-3a9vA:
15.46
3boyB-3a9vA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA3001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 10 HIS A  96
ILE A 175
GLY A  98
ALA A  99
HIS A  25
 None
 1.20A 3boyB-3a9vA:
undetectable
3boyC-3a9vA:
undetectable		 3boyB-3a9vA:
15.46
3boyC-3a9vA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 10 ILE A 126
ILE A  77
GLY A  70
PRO A 171
LEU A 157
 None
 1.20A 3elzC-3a9vA:
undetectable		 3elzC-3a9vA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		6 / 12 LEU A  41
GLY A 249
ALA A 250
ASP A 224
ILE A 274
ILE A 252
 None
 1.31A 3jw2B-3a9vA:
undetectable		 3jw2B-3a9vA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 THR A  58
ALA A  94
ILE A  71
ASP A  75
LEU A  92
 None
 1.15A 3lcvB-3a9vA:
undetectable		 3lcvB-3a9vA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 7 LEU A 227
HIS A 294
VAL A 281
SER A 284
 None
 0.85A 3r9vA-3a9vA:
undetectable
3r9vB-3a9vA:
undetectable		 3r9vA-3a9vA:
18.68
3r9vB-3a9vA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 11 PHE A 442
PHE A 233
PHE A 107
SER A  83
VAL A 281
 None
 1.33A 3u9fA-3a9vA:
0.0
3u9fC-3a9vA:
0.0		 3u9fA-3a9vA:
16.42
3u9fC-3a9vA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 PHE A 442
PHE A 233
PHE A 107
SER A  83
VAL A 281
 None
 1.42A 3u9fJ-3a9vA:
undetectable
3u9fL-3a9vA:
undetectable		 3u9fJ-3a9vA:
16.42
3u9fL-3a9vA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 11 PHE A 442
PHE A 233
PHE A 107
SER A  83
VAL A 281
 None
 1.36A 3u9fM-3a9vA:
undetectable
3u9fO-3a9vA:
undetectable		 3u9fM-3a9vA:
16.42
3u9fO-3a9vA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 6 ILE A 252
VAL A 272
LEU A 299
ILE A 274
 None
 0.74A 4asdA-3a9vA:
undetectable		 4asdA-3a9vA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 LYS A 394
THR A 199
ILE A 175
 None
 0.86A 4e0fB-3a9vA:
undetectable		 4e0fB-3a9vA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 LEU A 230
CYH A 244
ALA A 250
PHE A 220
LEU A 326
 None
 1.30A 4iaqA-3a9vA:
undetectable		 4iaqA-3a9vA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 8 PRO A 184
VAL A 196
GLN A 443
GLN A 391
 None
None
AMP  A 551 (-4.0A)
None
 1.01A 4iilA-3a9vA:
5.0		 4iilA-3a9vA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 ASP A 469
GLU A 474
LEU A 467
LEU A 436
ARG A 432
 None
None
None
None
AMP  A 551 (-4.5A)
 1.33A 4xi3A-3a9vA:
undetectable		 4xi3A-3a9vA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 5 GLY A 261
SER A 288
GLU A 259
ASP A 290
 None
 0.95A 4xueA-3a9vA:
2.9		 4xueA-3a9vA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		3 / 3 ARG A 300
ASP A 224
TYR A 219
 None
 0.69A 4yo9B-3a9vA:
undetectable		 4yo9B-3a9vA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		4 / 5 SER A  95
ALA A  94
HIS A  25
LEU A  92
 None
 1.45A 5dzkc-3a9vA:
undetectable
5dzkq-3a9vA:
undetectable		 5dzkc-3a9vA:
18.60
5dzkq-3a9vA:
1.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 3a9v 4-COUMARATE--COA
LIGASE
(Populus
tomentosa) 		5 / 12 GLN A 209
SER A 206
GLY A 202
LEU A 203
ILE A 385
 None
 1.49A 5fesA-3a9vA:
undetectable		 5fesA-3a9vA:
22.39