SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 PHE A 709
PHE A 659
ILE A 637
ILE A 640
PHE A 687
 None
None
None
MLY  A 641 ( 3.5A)
MLY  A 707 ( 4.4A)
 1.28A 2ft9A-3aagA:
undetectable		 2ft9A-3aagA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		4 / 6 ARG A 450
ASP A 452
ILE A 560
GLU A 510
 MLY  A 445 ( 3.3A)
None
None
MLY  A 471 ( 3.0A)
 1.39A 2ya7C-3aagA:
undetectable		 2ya7C-3aagA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 ASN A 691
TYR A 645
ASN A 638
SER A 664
GLN A 670
 None
MLY  A 646 ( 4.1A)
None
None
None
 1.28A 3bwmA-3aagA:
undetectable		 3bwmA-3aagA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 PHE A 550
MET A 529
LEU A 542
PHE A 541
ALA A 490
 MLY  A 551 ( 4.1A)
None
None
None
None
 1.00A 3nxuB-3aagA:
undetectable		 3nxuB-3aagA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A 491
ALA A 682
LEU A 562
LYS A 695
ILE A 560
 None
MLY  A 493 ( 3.6A)
None
MLY  A 694 ( 3.3A)
None
 1.12A 3ut5B-3aagA:
undetectable		 3ut5B-3aagA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A 491
ALA A 682
LEU A 562
LYS A 695
ILE A 560
 None
MLY  A 493 ( 3.6A)
None
MLY  A 694 ( 3.3A)
None
 1.13A 3ut5D-3aagA:
undetectable		 3ut5D-3aagA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A 491
ALA A 682
LEU A 562
LYS A 695
ILE A 560
 None
MLY  A 493 ( 3.6A)
None
MLY  A 694 ( 3.3A)
None
 1.11A 4x1yB-3aagA:
undetectable		 4x1yB-3aagA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		5 / 12 ASN A 691
TYR A 645
ASN A 638
SER A 664
GLN A 670
 None
MLY  A 646 ( 4.1A)
None
None
None
 1.27A 4xueA-3aagA:
1.5		 4xueA-3aagA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		3 / 3 SER A 536
LEU A 504
MET A 529
 None
 0.60A 5ikrB-3aagA:
undetectable		 5ikrB-3aagA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5P9I_A_1E8A701_2
(TYROSINE-PROTEIN
KINASE BTK)		 3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN
(Campylobacter
jejuni) 		4 / 5 LEU A 440
TYR A 563
MET A 564
ASP A 698
 None
 1.23A 5p9iA-3aagA:
undetectable		 5p9iA-3aagA:
23.38