SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aak'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MRA_B_DM2B204_1
(SORCIN)		 3aak PROGRAMMED CELL
DEATH PROTEIN 6
(Homo
sapiens) 		4 / 6 THR A 162
ARG A 166
ASP A 169
GLY A 174
 None
 0.59A 5mraA-3aakA:
12.7
5mraB-3aakA:
7.7		 5mraA-3aakA:
36.93
5mraB-3aakA:
36.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3aak PROGRAMMED CELL
DEATH PROTEIN 6
(Homo
sapiens) 		5 / 12 ALA A 122
ALA A 118
LEU A 134
ILE A 133
LEU A 126
 None
 1.15A 6aybA-3aakA:
undetectable		 6aybA-3aakA:
15.45