SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ab0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
(Mus
musculus) 		6 / 12 TYR C  36
GLN C  89
PHE C  98
VAL B  37
ALA B  96
TRP B 106
 None
 0.76A 1h8sA-3ab0C:
19.8		 1h8sA-3ab0C:
37.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
(Mus
musculus) 		5 / 11 SER B  35
TRP B  47
SER B  50
GLY B 100
PRO C  96
 None
 0.98A 1i9jH-3ab0B:
22.2
1i9jL-3ab0B:
14.4		 1i9jH-3ab0B:
58.02
1i9jL-3ab0B:
22.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
(Mus
musculus) 		5 / 12 SER B  35
TRP B  47
SER B  50
GLY B 100
PRO C  96
 None
 1.10A 1vpoH-3ab0B:
22.4
1vpoL-3ab0B:
14.0		 1vpoH-3ab0B:
42.99
1vpoL-3ab0B:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3ab0 BCLA PROTEIN
ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
(Bacillus
anthracis;
Mus
musculus) 		3 / 3 ASP A 124
ARG B  99
ASP A 103
 None
 0.96A 1vptA-3ab0A:
undetectable		 1vptA-3ab0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3ab0 BCLA PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A 167
ILE A 174
VAL A 105
LEU A 200
SER A 146
 None
 1.34A 2bxeA-3ab0A:
undetectable		 2bxeA-3ab0A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F38_A_15MA325_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
(Mus
musculus) 		5 / 12 SER B  50
PHE C  98
PHE B 103
PRO C  44
TYR C  87
 None
 1.37A 2f38A-3ab0B:
0.0		 2f38A-3ab0B:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
(Mus
musculus) 		4 / 6 SER B  50
PRO C  96
SER B  35
VAL B  37
 None
 1.21A 2hdnI-3ab0B:
undetectable
2hdnJ-3ab0B:
undetectable
2hdnL-3ab0B:
undetectable		 2hdnI-3ab0B:
14.29
2hdnJ-3ab0B:
16.51
2hdnL-3ab0B:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 5 ASN B  73
THR B  57
SER B  52
SER A 119
 None
 1.27A 3hlwB-3ab0B:
undetectable		 3hlwB-3ab0B:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ab0 BCLA PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A 136
THR A 180
ILE A 118
ILE A 128
SER A 187
 None
 1.28A 3kpbC-3ab0A:
undetectable		 3kpbC-3ab0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ab0 BCLA PROTEIN
(Bacillus
anthracis) 		5 / 10 ILE A 136
THR A 180
ILE A 118
ILE A 128
SER A 187
 None
 1.27A 3kpbD-3ab0A:
undetectable		 3kpbD-3ab0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.68A 5bs8A-3ab0C:
undetectable
5bs8C-3ab0C:
undetectable
5bs8D-3ab0C:
undetectable		 5bs8A-3ab0C:
13.29
5bs8C-3ab0C:
13.29
5bs8D-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.66A 5bs8A-3ab0C:
undetectable
5bs8B-3ab0C:
undetectable
5bs8C-3ab0C:
undetectable		 5bs8A-3ab0C:
13.29
5bs8B-3ab0C:
14.23
5bs8C-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.86A 5btaA-3ab0C:
undetectable
5btaC-3ab0C:
undetectable
5btaD-3ab0C:
undetectable		 5btaA-3ab0C:
13.29
5btaC-3ab0C:
13.29
5btaD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 6 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.86A 5btaA-3ab0C:
undetectable
5btaB-3ab0C:
undetectable
5btaC-3ab0C:
undetectable		 5btaA-3ab0C:
13.29
5btaB-3ab0C:
14.23
5btaC-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 6 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.88A 5btcA-3ab0C:
undetectable
5btcC-3ab0C:
undetectable
5btcD-3ab0C:
undetectable		 5btcA-3ab0C:
13.29
5btcC-3ab0C:
13.29
5btcD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 6 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.86A 5btcA-3ab0C:
undetectable
5btcB-3ab0C:
undetectable
5btcC-3ab0C:
undetectable		 5btcA-3ab0C:
13.29
5btcB-3ab0C:
14.23
5btcC-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.64A 5btdA-3ab0C:
undetectable
5btdB-3ab0C:
undetectable
5btdC-3ab0C:
undetectable		 5btdA-3ab0C:
13.29
5btdB-3ab0C:
14.23
5btdC-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.67A 5btdA-3ab0C:
undetectable
5btdC-3ab0C:
undetectable
5btdD-3ab0C:
undetectable		 5btdA-3ab0C:
13.29
5btdC-3ab0C:
13.29
5btdD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.87A 5btfA-3ab0C:
undetectable
5btfB-3ab0C:
undetectable
5btfC-3ab0C:
undetectable		 5btfA-3ab0C:
13.29
5btfB-3ab0C:
14.23
5btfC-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.89A 5btfA-3ab0C:
undetectable
5btfC-3ab0C:
undetectable
5btfD-3ab0C:
undetectable		 5btfA-3ab0C:
13.29
5btfC-3ab0C:
13.29
5btfD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 6 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.71A 5btgA-3ab0C:
undetectable
5btgB-3ab0C:
undetectable
5btgC-3ab0C:
undetectable		 5btgA-3ab0C:
13.29
5btgB-3ab0C:
14.23
5btgC-3ab0C:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 7 ALA C  26
GLY A 157
THR A 125
GLU A 190
 None
 0.72A 5btgA-3ab0C:
undetectable
5btgC-3ab0C:
undetectable
5btgD-3ab0C:
undetectable		 5btgA-3ab0C:
13.29
5btgC-3ab0C:
13.29
5btgD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 5 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.84A 5btiA-3ab0C:
undetectable
5btiB-3ab0C:
undetectable		 5btiA-3ab0C:
13.29
5btiB-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ab0 ANTIBODY SCFV
FRAGMENT, LIGHT
CHAIN
BCLA PROTEIN
(Bacillus
anthracis;
Mus
musculus) 		4 / 5 SER C  28
GLY A 157
THR A 125
GLU A 190
 None
 0.86A 5btiC-3ab0C:
undetectable
5btiD-3ab0C:
undetectable		 5btiC-3ab0C:
13.29
5btiD-3ab0C:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_D_SAMD605_0
(GUANINE-N7
METHYLTRANSFERASE)		 3ab0 BCLA PROTEIN
ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
(Bacillus
anthracis;
Mus
musculus) 		5 / 10 GLY B 100
ASN B  98
ASP A 122
ALA A 123
GLN A 120
 None
 1.35A 5c8tD-3ab0B:
0.0		 5c8tD-3ab0B:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3ab0 ANTIBODY SCFV
FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLU B  88
ARG B  38
THR B  40
PRO B  41
 None
 1.31A 6a4iB-3ab0B:
undetectable		 6a4iB-3ab0B:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3ab0 BCLA PROTEIN
(Bacillus
anthracis) 		4 / 5 ASN A 108
VAL A 193
LEU A 198
SER A 205
 None
 0.87A 6a7pA-3ab0A:
undetectable		 6a7pA-3ab0A:
11.79