SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3acf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		5 / 12 ILE A 200
THR A  91
LEU A 177
PHE A 121
LEU A 171
 None
 1.39A 2mjiA-3acfA:
undetectable		 2mjiA-3acfA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		4 / 5 PRO A  82
SER A  80
LEU A  52
SER A  50
 None
 1.39A 3ijxH-3acfA:
undetectable		 3ijxH-3acfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		3 / 3 ALA A  12
VAL A  13
GLN A  49
 None
 0.68A 3of4B-3acfA:
undetectable		 3of4B-3acfA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		4 / 8 ASP A 102
HIS A 155
ASP A 198
GLU A 203
 None
None
CA  A 204 (-2.2A)
None
 0.98A 3sg9B-3acfA:
undetectable		 3sg9B-3acfA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		4 / 7 VAL A  67
TYR A  69
MET A 195
LEU A 105
 None
 1.06A 4hxyB-3acfA:
undetectable		 4hxyB-3acfA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		3 / 3 ASP A 186
LEU A 140
GLY A 113
 None
 0.54A 4xmfA-3acfA:
undetectable		 4xmfA-3acfA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		4 / 7 TYR A  69
VAL A  48
ILE A  84
LEU A 105
 None
 0.99A 4xo7B-3acfA:
undetectable		 4xo7B-3acfA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3acf BETA-1,4-ENDOGLUCANA
SE
([Clostridium]
josui) 		4 / 7 TYR A  69
VAL A  48
TRP A  42
ILE A  84
 None
 1.12A 4xo7B-3acfA:
undetectable		 4xo7B-3acfA:
20.68