SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3act'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLN A 395
HIS A 463
PRO A 449
 None
 0.84A 1d8cA-3actA:
undetectable		 1d8cA-3actA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 5 ARG A 367
ALA A 486
ASP A 423
GLY A 419
 K  A2903 (-4.0A)
None
None
None
 1.05A 1e7cA-3actA:
undetectable		 1e7cA-3actA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 5 TYR A 103
PRO A 122
LEU A 123
THR A 316
 None
 1.15A 1i2wA-3actA:
undetectable		 1i2wA-3actA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 4 GLY A  42
LEU A  37
GLY A  69
ARG A  70
 None
 1.28A 1j7kA-3actA:
undetectable		 1j7kA-3actA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ASP A 422
HIS A 403
ASP A 368
 None
 0.79A 1nw5A-3actA:
undetectable		 1nw5A-3actA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 MET A 600
ALA A 740
PHE A 685
ILE A 691
TYR A 695
 None
 1.10A 1osvA-3actA:
0.0		 1osvA-3actA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLU A 659
ASN A 489
TRP A 488
 BGC  A2901 (-2.8A)
None
K  A2903 (-4.0A)
 1.01A 1r15C-3actA:
undetectable		 1r15C-3actA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLU A 659
ASN A 489
TRP A 488
 BGC  A2901 (-2.8A)
None
K  A2903 (-4.0A)
 1.04A 1r15D-3actA:
undetectable		 1r15D-3actA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLU A 659
ASN A 489
TRP A 488
 BGC  A2901 (-2.8A)
None
K  A2903 (-4.0A)
 1.03A 1r15E-3actA:
undetectable		 1r15E-3actA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLU A 659
ASN A 489
TRP A 488
 BGC  A2901 (-2.8A)
None
K  A2903 (-4.0A)
 1.00A 1r15F-3actA:
undetectable		 1r15F-3actA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 VAL A 807
VAL A 797
LEU A 755
ASP A 798
 None
 1.00A 2ddwA-3actA:
undetectable		 2ddwA-3actA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 GLU A 675
VAL A 671
LEU A 633
ARG A 680
ALA A 682
 None
 1.22A 2jj8C-3actA:
undetectable		 2jj8C-3actA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 GLY A 732
CYH A 665
GLN A 712
PHE A 664
 PO4  A2902 (-3.5A)
None
PO4  A2902 (-3.8A)
BGC  A2901 (-4.7A)
 1.22A 2qx4A-3actA:
undetectable
2qx4B-3actA:
undetectable		 2qx4A-3actA:
14.55
2qx4B-3actA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 SER A 518
ILE A 521
ASP A 422
ARG A 367
 None
None
None
K  A2903 (-4.0A)
 0.74A 2v57A-3actA:
undetectable		 2v57A-3actA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 SER A 518
ILE A 521
ASP A 422
ARG A 367
 None
None
None
K  A2903 (-4.0A)
 0.72A 2v57C-3actA:
undetectable		 2v57C-3actA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLY A 681
GLY A 787
GLY A 762
 None
 0.36A 3bogC-3actA:
undetectable		 3bogC-3actA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLY A 681
GLY A 787
GLY A 762
 None
 0.36A 3bogD-3actA:
undetectable		 3bogD-3actA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ASP A 211
PHE A 147
SER A 228
 None
 0.69A 3i5uB-3actA:
undetectable		 3i5uB-3actA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ARG A   2
ASP A 701
ASP A 698
 None
 0.90A 3jayA-3actA:
undetectable		 3jayA-3actA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ARG A   2
ASP A 701
ASP A 698
 None
 0.89A 3jb2A-3actA:
undetectable		 3jb2A-3actA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 THR A 189
GLY A 242
ALA A 240
ILE A 185
 None
 0.78A 3jusB-3actA:
undetectable		 3jusB-3actA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 11 SER A  84
THR A  82
ALA A  67
GLY A  68
ALA A  41
 None
 1.32A 3mg0H-3actA:
undetectable
3mg0I-3actA:
undetectable		 3mg0H-3actA:
12.96
3mg0I-3actA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 10 PHE A 664
LEU A 494
ASN A 493
LEU A 647
VAL A 650
 BGC  A2901 (-4.7A)
None
None
None
None
 1.24A 3o02A-3actA:
1.7
3o02B-3actA:
1.8		 3o02A-3actA:
17.92
3o02B-3actA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 ASP A 423
ILE A 391
ASP A 490
ARG A 367
ASP A 368
 None
None
K  A2903 ( 3.4A)
K  A2903 (-4.0A)
None
 1.22A 3phaB-3actA:
undetectable		 3phaB-3actA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 ASP A 423
ILE A 391
ASP A 490
ARG A 367
ASP A 368
 None
None
K  A2903 ( 3.4A)
K  A2903 (-4.0A)
None
 1.20A 3phaD-3actA:
undetectable		 3phaD-3actA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 LEU A 146
VAL A 253
VAL A 115
ASP A  76
 None
 0.97A 3rgfA-3actA:
undetectable		 3rgfA-3actA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ASN A 287
ALA A 279
LYS A 288
 None
 0.98A 3runA-3actA:
undetectable		 3runA-3actA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 ARG A  54
ALA A  50
MET A 349
ALA A 353
 None
 0.87A 3tx2A-3actA:
undetectable		 3tx2A-3actA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLN A 469
PHE A 468
TYR A 551
 None
 0.99A 3ucjB-3actA:
undetectable		 3ucjB-3actA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLN A 469
PHE A 468
TYR A 551
 None
 1.00A 3ucjA-3actA:
undetectable		 3ucjA-3actA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.70A 3warA-3actA:
undetectable		 3warA-3actA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 5 HIS A 378
GLN A 340
SER A 323
VAL A 770
 None
 1.36A 4a99D-3actA:
undetectable		 4a99D-3actA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 THR A 143
ALA A 252
SER A 250
THR A 145
 None
 0.99A 4d7bA-3actA:
undetectable		 4d7bA-3actA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 6 ARG A 749
ILE A 781
VAL A 820
LEU A 795
 None
 0.87A 4em2A-3actA:
undetectable		 4em2A-3actA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 GLY A 661
GLY A 662
MET A 713
GLU A 718
 None
 0.63A 4fgkB-3actA:
undetectable		 4fgkB-3actA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 5 GLY A 661
GLY A 662
MET A 713
GLU A 718
 None
 0.62A 4fglC-3actA:
undetectable		 4fglC-3actA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 6 GLY A 661
GLY A 662
MET A 713
GLU A 718
 None
 0.66A 4fglD-3actA:
undetectable		 4fglD-3actA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 6 ARG A 367
GLY A 365
ASN A 413
GLN A 712
 K  A2903 (-4.0A)
None
None
PO4  A2902 (-3.8A)
 1.21A 4g0vB-3actA:
undetectable		 4g0vB-3actA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 6 ILE A  25
TYR A  60
TYR A  44
TYR A  58
 None
 1.01A 4g10A-3actA:
undetectable		 4g10A-3actA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 11 PHE A 664
GLY A 661
ALA A 715
ILE A  25
LEU A  36
 BGC  A2901 (-4.7A)
None
None
None
None
 1.05A 4kt0A-3actA:
2.4
4kt0J-3actA:
undetectable		 4kt0A-3actA:
21.08
4kt0J-3actA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 TYR A 265
THR A 205
LEU A 146
VAL A 251
 None
 1.01A 4l4aA-3actA:
undetectable		 4l4aA-3actA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ASP A 422
ASN A 489
SER A 418
 None
 0.87A 4obwA-3actA:
undetectable		 4obwA-3actA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 ARG A 110
ASP A  79
TRP A  81
 None
 1.07A 4xdqA-3actA:
undetectable		 4xdqA-3actA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 4 PHE A 147
ASP A 208
GLY A 233
SER A 250
 None
 1.32A 4xp9C-3actA:
0.0		 4xp9C-3actA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 4 GLY A 171
VAL A 173
PHE A 217
ILE A 246
 None
 1.04A 4xv2B-3actA:
undetectable		 4xv2B-3actA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 4 GLY A 242
VAL A 173
PHE A 217
ILE A 246
 None
 1.08A 4xv2B-3actA:
undetectable		 4xv2B-3actA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 7 ARG A 105
LEU A 118
GLN A 130
PHE A 120
LEU A 308
 None
 1.47A 5b1aP-3actA:
undetectable
5b1aW-3actA:
undetectable		 5b1aP-3actA:
13.52
5b1aW-3actA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 7 ARG A 105
LEU A 118
GLN A 130
PHE A 120
LEU A 308
 None
 1.48A 5b3sP-3actA:
undetectable		 5b3sP-3actA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		3 / 3 GLU A 517
HIS A 478
ASP A 574
 None
 0.81A 5c0oG-3actA:
undetectable		 5c0oG-3actA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 4 ASN A 495
SER A 518
ALA A 516
VAL A 515
 None
 1.04A 5nm5A-3actA:
undetectable		 5nm5A-3actA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 ASP A 490
ILE A 521
ASP A 422
ARG A 367
LEU A 635
 K  A2903 ( 3.4A)
None
None
K  A2903 (-4.0A)
None
 1.33A 5nn8A-3actA:
5.4		 5nn8A-3actA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.77A 5y9mA-3actA:
undetectable		 5y9mA-3actA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 8 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.72A 5y9mX-3actA:
undetectable		 5y9mX-3actA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.72A 5yf9B-3actA:
undetectable		 5yf9B-3actA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 7 VAL A 264
VAL A 129
LYS A 131
ASP A 305
 None
 0.80A 5ywmX-3actA:
undetectable		 5ywmX-3actA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 GLY A 529
ALA A 523
ALA A 522
VAL A 519
SER A 518
 None
 1.06A 6c2mC-3actA:
undetectable		 6c2mC-3actA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		4 / 6 GLN A 342
GLU A 706
HIS A 703
ALA A 711
 None
 1.16A 6f6jC-3actA:
undetectable
6f6jD-3actA:
undetectable		 6f6jC-3actA:
18.76
6f6jD-3actA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 3act CELLOBIOSE
PHOSPHORYLASE
(Cellulomonas
gilvus) 		5 / 12 PHE A 468
ILE A 428
ASN A 370
LEU A 373
ALA A 392
 None
 1.11A 6r2eE-3actA:
undetectable		 6r2eE-3actA:
17.18