SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ad9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 LEU C 163
LEU C 156
LEU C 122
LEU C 124
 None
 0.99A 2ab2A-3ad9C:
undetectable		 2ab2A-3ad9C:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 5 LEU C 163
LEU C 156
LEU C 122
LEU C 124
 None
 0.98A 2ab2B-3ad9C:
undetectable		 2ab2B-3ad9C:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C 166
ALA C 151
THR C 180
VAL C 184
THR C 183
 None
 1.05A 3czhA-3ad9C:
undetectable		 3czhA-3ad9C:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C 166
ALA C 151
THR C 180
VAL C 184
THR C 183
 None
 1.08A 3czhB-3ad9C:
undetectable		 3czhB-3ad9C:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 4 LEU C 115
GLY C  42
LEU C  88
GLU C  86
 None
 0.97A 3tgvB-3ad9C:
undetectable		 3tgvB-3ad9C:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 ILE C 159
HIS C 185
LEU C 187
HIS C 182
 None
 0.97A 5hrqE-3ad9C:
undetectable
5hrqF-3ad9C:
undetectable
5hrqJ-3ad9C:
undetectable		 5hrqE-3ad9C:
8.63
5hrqF-3ad9C:
12.16
5hrqJ-3ad9C:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C  38
THR C  39
SER C  75
GLY C  76
ALA C  78
 None
 1.31A 5l5zV-3ad9C:
undetectable
5l5zb-3ad9C:
undetectable		 5l5zV-3ad9C:
25.86
5l5zb-3ad9C:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C  38
THR C  39
SER C  75
GLY C  76
ALA C  78
 None
 1.31A 5l5zH-3ad9C:
undetectable
5l5zN-3ad9C:
undetectable		 5l5zH-3ad9C:
25.86
5l5zN-3ad9C:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C  38
THR C  39
SER C  75
GLY C  76
ALA C  78
 None
 1.32A 5lf3b-3ad9C:
undetectable		 5lf3b-3ad9C:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 THR C  38
THR C  39
SER C  75
GLY C  76
ALA C  78
 None
 1.33A 5lf3N-3ad9C:
undetectable		 5lf3N-3ad9C:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 LEU C 163
ILE C 152
VAL C  24
GLY C 147
LEU C 141
 None
 1.13A 6a7pA-3ad9C:
undetectable		 6a7pA-3ad9C:
17.15