SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ada'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 8 GLY B 198
LYS B 210
THR B 211
GLY B 208
LEU B  51
 None
 1.16A 1aegA-3adaB:
undetectable		 1aegA-3adaB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 LEU B 136
VAL B 144
VAL B 106
GLN B 164
 None
 0.89A 1e7aB-3adaB:
undetectable		 1e7aB-3adaB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 GLY B 355
ARG B  69
MET B 264
ILE B  67
TYR B 271
 FAD  B   1 (-3.4A)
None
None
FAD  B   1 (-3.7A)
None
 1.16A 1pn0A-3adaB:
17.1		 1pn0A-3adaB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 GLY B 355
ARG B  69
MET B 264
ILE B  67
TYR B 271
 FAD  B   1 (-3.4A)
None
None
FAD  B   1 (-3.7A)
None
 1.16A 1pn0B-3adaB:
5.0		 1pn0B-3adaB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 GLY B 355
ARG B  69
MET B 264
ILE B  67
TYR B 271
 FAD  B   1 (-3.4A)
None
None
FAD  B   1 (-3.7A)
None
 1.18A 1pn0C-3adaB:
2.6		 1pn0C-3adaB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 GLY B 355
ARG B  69
MET B 264
ILE B  67
TYR B 271
 FAD  B   1 (-3.4A)
None
None
FAD  B   1 (-3.7A)
None
 1.18A 1pn0D-3adaB:
2.6		 1pn0D-3adaB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 0.99A 1rxcD-3adaB:
undetectable		 1rxcD-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.08A 1rxcL-3adaB:
undetectable		 1rxcL-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 0.96A 1wmqA-3adaB:
undetectable		 1wmqA-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 0.96A 1wmqB-3adaB:
undetectable		 1wmqB-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 0.94A 1wpuA-3adaB:
undetectable		 1wpuA-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 0.95A 1wpuB-3adaB:
undetectable		 1wpuB-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 0.99A 1wrqA-3adaB:
undetectable		 1wrqA-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ARG B 104
ILE B 169
GLY B 168
ALA B 167
 None
 1.00A 1wrqB-3adaB:
undetectable		 1wrqB-3adaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 GLU B  52
GLY B  32
GLY B  29
ILE B 191
LEU B  51
 FAD  B   1 (-2.8A)
None
FAD  B   1 (-3.0A)
None
None
 1.11A 1x7pA-3adaB:
undetectable
1x7pB-3adaB:
undetectable		 1x7pA-3adaB:
21.67
1x7pB-3adaB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 8 VAL B 144
THR B 137
TYR B 163
LEU B 107
 None
 1.01A 1z2bB-3adaB:
undetectable		 1z2bB-3adaB:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 GLY B  27
GLY B  28
VAL B 196
LEU B 232
 FAD  B   1 (-3.3A)
FAD  B   1 ( 4.8A)
FAD  B   1 (-4.0A)
FAD  B   1 (-4.6A)
 0.68A 2oa1B-3adaB:
13.9		 2oa1B-3adaB:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 8 TYR B 292
GLN B 294
ARG B  63
ILE B 327
 None
None
FMN  B   4 ( 3.1A)
None
 1.10A 2xytH-3adaB:
undetectable		 2xytH-3adaB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 11 ALA B 334
PHE B 388
ILE B 242
GLY B 351
ARG B 387
 None
 1.07A 3bpxA-3adaB:
undetectable
3bpxB-3adaB:
undetectable		 3bpxA-3adaB:
16.76
3bpxB-3adaB:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 LEU B 107
VAL B 272
PRO B 260
THR B 261
VAL B 263
 None
 0.76A 3gguA-3adaB:
undetectable		 3gguA-3adaB:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.11A 3kvvA-3adaB:
undetectable		 3kvvA-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.10A 3kvvB-3adaB:
undetectable		 3kvvB-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.12A 3kvvC-3adaB:
undetectable		 3kvvC-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.13A 3kvvE-3adaB:
undetectable		 3kvvE-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.12A 3kvvF-3adaB:
undetectable		 3kvvF-3adaB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 LEU B 107
VAL B 272
PRO B 260
THR B 261
VAL B 263
 None
 0.84A 3so9B-3adaB:
undetectable		 3so9B-3adaB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 5 TYR B 292
SER B 229
ASP B 287
ILE B 286
 None
 1.37A 3uj7B-3adaB:
undetectable		 3uj7B-3adaB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 ILE B 338
SER B  84
LEU B  85
PHE B 101
VAL B 175
 None
 1.09A 3w68B-3adaB:
undetectable		 3w68B-3adaB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 11 GLN B 294
GLY B 326
ALA B 224
GLY B  27
ASN B 349
 None
FAD  B   1 (-3.5A)
None
FAD  B   1 (-3.3A)
None
 1.32A 4a6nA-3adaB:
14.8		 4a6nA-3adaB:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		3 / 3 GLU B  82
GLY B 130
SER B  70
 None
 0.67A 4b53B-3adaB:
undetectable		 4b53B-3adaB:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 GLY B  28
MET B  61
ILE B 190
VAL B  50
 FAD  B   1 ( 4.8A)
FAD  B   1 (-3.8A)
None
None
 1.12A 4e1vF-3adaB:
undetectable		 4e1vF-3adaB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 TRP B  12
GLY B  28
GLY B  29
MET B  61
VAL B  48
 None
FAD  B   1 ( 4.8A)
FAD  B   1 (-3.0A)
FAD  B   1 (-3.8A)
None
 1.37A 4fgkA-3adaB:
undetectable
4fgkB-3adaB:
0.6		 4fgkA-3adaB:
20.90
4fgkB-3adaB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 8 ASN B  60
GLY B 356
THR B 360
GLY B  32
 FAD  B   1 (-3.9A)
FAD  B   1 (-3.0A)
None
None
 0.84A 4fo4B-3adaB:
undetectable		 4fo4B-3adaB:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 CYH B 350
GLY B 356
GLY B 355
LEU B 223
LEU B 240
 None
FAD  B   1 (-3.0A)
FAD  B   1 (-3.4A)
None
None
 0.89A 4fp9A-3adaB:
undetectable		 4fp9A-3adaB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 CYH B 350
GLY B 356
GLY B 355
LEU B 223
LEU B 240
 None
FAD  B   1 (-3.0A)
FAD  B   1 (-3.4A)
None
None
 0.89A 4fp9C-3adaB:
2.2		 4fp9C-3adaB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 CYH B 350
GLY B 356
GLY B 355
LEU B 223
LEU B 240
 None
FAD  B   1 (-3.0A)
FAD  B   1 (-3.4A)
None
None
 0.88A 4fp9D-3adaB:
undetectable		 4fp9D-3adaB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 CYH B 350
GLY B 356
GLY B 355
LEU B 223
LEU B 240
 None
FAD  B   1 (-3.0A)
FAD  B   1 (-3.4A)
None
None
 0.90A 4fp9F-3adaB:
undetectable		 4fp9F-3adaB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 CYH B 350
GLY B 356
GLY B 355
LEU B 223
LEU B 240
 None
FAD  B   1 (-3.0A)
FAD  B   1 (-3.4A)
None
None
 0.88A 4fzvA-3adaB:
undetectable		 4fzvA-3adaB:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 11 GLY B  30
GLY B  29
GLY B  28
ALA B  34
LEU B  33
 FAD  B   1 (-3.6A)
FAD  B   1 (-3.0A)
FAD  B   1 ( 4.8A)
None
None
 0.84A 4l8fB-3adaB:
undetectable		 4l8fB-3adaB:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 11 GLY B  30
GLY B  29
GLY B  28
ALA B  34
LEU B  33
 FAD  B   1 (-3.6A)
FAD  B   1 (-3.0A)
FAD  B   1 ( 4.8A)
None
None
 0.87A 4l8fD-3adaB:
undetectable		 4l8fD-3adaB:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		3 / 3 PRO B 336
ASN B 349
HIS B  31
 None
None
FAD  B   1 (-3.8A)
 0.83A 4ma3H-3adaB:
undetectable
4ma3L-3adaB:
undetectable		 4ma3H-3adaB:
17.11
4ma3L-3adaB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		3 / 3 THR B 162
ASN B 129
PHE B 128
 None
 0.62A 4pd9A-3adaB:
undetectable		 4pd9A-3adaB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		3 / 3 ILE B 268
ASP B 115
ARG B 155
 None
 0.67A 4pstA-3adaB:
undetectable		 4pstA-3adaB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 ILE B 338
THR B 331
ILE B 242
LEU B 240
ILE B 337
 None
 1.08A 4pthA-3adaB:
undetectable		 4pthA-3adaB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		3 / 3 GLU B  52
ILE B 327
ALA B  62
 FAD  B   1 (-2.8A)
None
FMN  B   4 (-4.1A)
 0.57A 4wnwB-3adaB:
undetectable		 4wnwB-3adaB:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 11 VAL B  48
TRP B  12
GLY B  28
GLY B  29
MET B  61
 None
None
FAD  B   1 ( 4.8A)
FAD  B   1 (-3.0A)
FAD  B   1 (-3.8A)
 1.39A 4zvmA-3adaB:
undetectable
4zvmB-3adaB:
2.2		 4zvmA-3adaB:
20.90
4zvmB-3adaB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 ILE B 147
GLY B 151
ASN B 153
ILE B 148
 None
 0.95A 5j4nB-3adaB:
undetectable		 5j4nB-3adaB:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 GLY B 398
ASP B 115
HIS B 269
ASN B 108
 None
 0.91A 5nnwD-3adaB:
undetectable		 5nnwD-3adaB:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 7 GLY B 398
ASP B 115
HIS B 269
ASN B 108
 None
 0.91A 5no9D-3adaB:
undetectable		 5no9D-3adaB:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 ILE B 242
PHE B 199
ILE B  25
ALA B 222
LEU B 223
 None
 1.28A 5oy02-3adaB:
undetectable		 5oy02-3adaB:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 12 LEU B 232
LEU B 346
ILE B 338
LEU B 367
LEU B 385
 FAD  B   1 (-4.6A)
None
None
None
None
 1.11A 5toaB-3adaB:
undetectable		 5toaB-3adaB:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 6 SER B  77
ALA B 334
SER B 335
ALA B 399
 None
 0.99A 6bocA-3adaB:
undetectable
6bocB-3adaB:
undetectable
6bocC-3adaB:
undetectable
6bocD-3adaB:
undetectable		 6bocA-3adaB:
4.88
6bocB-3adaB:
4.88
6bocC-3adaB:
4.88
6bocD-3adaB:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		5 / 10 LEU B 393
ASP B 395
ILE B 242
SER B 335
GLY B 351
 None
 1.14A 6dm0B-3adaB:
undetectable
6dm0C-3adaB:
2.0		 6dm0B-3adaB:
12.07
6dm0C-3adaB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 8 GLY B 356
PHE B 357
GLY B  32
ALA B 176
 FAD  B   1 (-3.0A)
None
None
None
 0.73A 6hu9H-3adaB:
undetectable
6hu9e-3adaB:
undetectable		 6hu9H-3adaB:
10.50
6hu9e-3adaB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3ada SARCOSINE OXIDASE
BETA SUBUNIT
(Corynebacterium
sp.
U-96) 		4 / 8 ARG B 121
ALA B 125
ALA B  78
GLU B 396
 None
 0.71A 6mdqA-3adaB:
undetectable		 6mdqA-3adaB:
12.98