SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3adc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 4 ILE A  23
LEU A  24
VAL A  31
ALA A  65
 None
 0.90A 1mz9A-3adcA:
undetectable		 1mz9A-3adcA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 5 ILE A  23
LEU A  24
VAL A  31
ALA A  65
 None
 0.96A 1mz9C-3adcA:
undetectable		 1mz9C-3adcA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ILE A 159
LEU A  20
PHE A 156
LEU A 102
 None
 0.92A 1v55N-3adcA:
3.2
1v55W-3adcA:
undetectable		 1v55N-3adcA:
16.54
1v55W-3adcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 4 LEU A 244
SER A 247
TYR A 248
LEU A 218
 None
 1.08A 1xz1A-3adcA:
undetectable		 1xz1A-3adcA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 4 LEU A 244
SER A 247
TYR A 248
LEU A 218
 None
 1.08A 1xz3A-3adcA:
undetectable		 1xz3A-3adcA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  62
LEU A  34
ARG A  83
THR A  76
 None
None
None
A  C  76 ( 3.6A)
 1.09A 2zxwN-3adcA:
3.7
2zxwW-3adcA:
undetectable		 2zxwN-3adcA:
16.54
2zxwW-3adcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 8 GLY A 136
GLU A 134
ILE A  99
PHE A 145
 None
 0.89A 3aodA-3adcA:
undetectable		 3aodA-3adcA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ILE A 159
LEU A  20
PHE A 156
LEU A 102
 None
 0.91A 3asoN-3adcA:
2.9
3asoW-3adcA:
undetectable		 3asoN-3adcA:
16.54
3asoW-3adcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A 244
SER A 247
TYR A 248
LEU A 218
 None
 1.07A 3ravA-3adcA:
undetectable		 3ravA-3adcA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A  95
PRO A 171
LYS A  -1
 None
 1.19A 4dr5L-3adcA:
undetectable		 4dr5L-3adcA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A  95
PRO A 171
LYS A  -1
 None
 1.17A 4dr6L-3adcA:
undetectable		 4dr6L-3adcA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A  95
PRO A 171
LYS A  -1
 None
 1.25A 4duzL-3adcA:
undetectable		 4duzL-3adcA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A  95
PRO A 171
LYS A  -1
 None
 1.35A 4dv7L-3adcA:
undetectable		 4dv7L-3adcA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3adc L-SERYL-TRNA(SEC)
KINASE
(Methanocaldococc
us
jannaschii) 		4 / 4 ILE A  39
ILE A  54
ARG A  40
LEU A  61
 None
None
C  C  75 ( 3.1A)
None
 1.18A 5dzkh-3adcA:
undetectable
5dzkn-3adcA:
undetectable
5dzkv-3adcA:
undetectable		 5dzkh-3adcA:
23.37
5dzkn-3adcA:
23.37
5dzkv-3adcA:
0.78