SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3adk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		5 / 12 SER A  51
GLY A  54
MET A  56
LEU A  57
GLU A  70
 None
 1.32A 1a27A-3adkA:
3.3		 1a27A-3adkA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 5 GLY A  22
GLN A  24
VAL A  13
SER A  19
 SO4  A 195 (-3.6A)
None
None
SO4  A 195 (-3.6A)
 1.15A 1p6kB-3adkA:
undetectable		 1p6kB-3adkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 5 GLY A  22
GLN A  24
VAL A  13
SER A  19
 SO4  A 195 (-3.6A)
None
None
SO4  A 195 (-3.6A)
 1.13A 1rs6B-3adkA:
undetectable		 1rs6B-3adkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 5 GLY A  22
GLN A  24
VAL A  13
SER A  19
 SO4  A 195 (-3.6A)
None
None
SO4  A 195 (-3.6A)
 1.26A 1zzqB-3adkA:
undetectable		 1zzqB-3adkA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 5 GLY A  22
GLN A  24
VAL A  13
SER A  19
 SO4  A 195 (-3.6A)
None
None
SO4  A 195 (-3.6A)
 1.17A 1zzuB-3adkA:
undetectable		 1zzuB-3adkA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		3 / 3 THR A 124
PRO A 122
THR A 126
 None
 0.78A 209dC-3adkA:
undetectable		 209dC-3adkA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 8 GLY A  89
ILE A 169
VAL A  14
SER A   8
 None
 0.93A 2yoeB-3adkA:
undetectable
2yoeC-3adkA:
undetectable		 2yoeB-3adkA:
18.57
2yoeC-3adkA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 6 ARG A 167
GLN A 111
PHE A  12
LEU A 115
 None
 1.15A 3tgvB-3adkA:
undetectable		 3tgvB-3adkA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		3 / 3 SER A  58
MET A  61
ASP A  74
 None
 0.97A 4mm4B-3adkA:
undetectable		 4mm4B-3adkA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 4 ALA A  79
VAL A  84
GLY A  89
THR A  35
 None
 1.14A 4ubeA-3adkA:
3.5		 4ubeA-3adkA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3adk ADENYLATE KINASE
(Sus
scrofa) 		4 / 5 GLY A  22
GLN A  24
VAL A  13
SER A  19
 SO4  A 195 (-3.6A)
None
None
SO4  A 195 (-3.6A)
 1.18A 5vunA-3adkA:
undetectable		 5vunA-3adkA:
20.00