SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3adp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 4 SER A 123
SER A 121
LEU A  99
PHE A 106
 NAI  A1001 ( 4.8A)
None
None
None
 1.46A 1r5lA-3adpA:
0.3		 1r5lA-3adpA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 10 ARG A  50
LEU A  72
ILE A  11
GLY A  18
ILE A  75
 None
 0.93A 1sdtA-3adpA:
undetectable		 1sdtA-3adpA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 10 ARG A  50
LEU A  72
ILE A  11
GLY A  18
ILE A  75
 None
 0.95A 1sdvA-3adpA:
undetectable		 1sdvA-3adpA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 6 LEU A 109
PHE A 106
ALA A 107
LEU A  81
 None
 0.99A 1ukbA-3adpA:
undetectable		 1ukbA-3adpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 6 HIS A 145
ASN A 196
GLN A 199
PRO A 149
 NAI  A1001 (-4.6A)
None
None
None
 1.30A 2ez7A-3adpA:
undetectable		 2ez7A-3adpA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 5 ASP A 303
LEU A 306
LYS A 307
ARG A 302
 None
 1.42A 2gj5A-3adpA:
undetectable		 2gj5A-3adpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 ARG A  50
LEU A  72
ILE A  11
GLY A  18
ILE A  75
 None
 0.97A 2r5pA-3adpA:
undetectable		 2r5pA-3adpA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 ARG A  50
LEU A  72
ILE A  11
GLY A  18
ILE A  75
 None
 0.98A 2r5pC-3adpA:
undetectable		 2r5pC-3adpA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 4 THR A  43
ARG A  19
GLU A  47
ASN A  48
 None
 1.46A 2w13A-3adpA:
0.0		 2w13A-3adpA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 PHE A  25
VAL A   9
PHE A 106
PHE A 132
ALA A 144
 None
 1.49A 3apwA-3adpA:
undetectable		 3apwA-3adpA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 PHE A  25
VAL A   9
PHE A 106
PHE A 132
ALA A 144
 None
 1.43A 3apxA-3adpA:
undetectable		 3apxA-3adpA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 9 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.00A 3ekqB-3adpA:
undetectable		 3ekqB-3adpA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.04A 3k4vC-3adpA:
undetectable		 3k4vC-3adpA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 12 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.02A 3nduC-3adpA:
undetectable		 3nduC-3adpA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		4 / 7 ALA A 144
SER A 120
VAL A 118
LEU A 158
 None
 0.88A 3o14A-3adpA:
undetectable		 3o14A-3adpA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		3 / 3 LYS A  63
ARG A 314
ASP A 303
 None
 1.41A 3o7wA-3adpA:
4.1		 3o7wA-3adpA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 10 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.06A 4njuB-3adpA:
undetectable		 4njuB-3adpA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 10 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.06A 4njuD-3adpA:
undetectable		 4njuD-3adpA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 3adp LAMBDA-CRYSTALLIN
(Oryctolagus
cuniculus) 		5 / 9 ARG A  50
LEU A  72
VAL A  32
GLY A  18
ILE A  75
 None
 1.02A 5kqxB-3adpA:
undetectable		 5kqxB-3adpA:
15.41