SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3adr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 5 HIS A  63
SER A   8
LEU A   6
GLY A 204
 ZN  A 263 (-3.4A)
EDO  A 268 (-4.0A)
EDO  A 270 ( 4.8A)
None
 0.96A 1a4lB-3adrA:
undetectable		 1a4lB-3adrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 5 ASP A  92
GLU A  91
LEU A  97
LEU A  94
 EDO  A 267 (-3.6A)
None
None
EDO  A 265 ( 4.5A)
 1.18A 1np1A-3adrA:
undetectable		 1np1A-3adrA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  94
LEU A  97
ASN A  98
LEU A 119
LEU A  67
 EDO  A 265 ( 4.5A)
None
None
EDO  A 265 ( 4.7A)
EDO  A 265 ( 4.4A)
 1.14A 1sqnB-3adrA:
undetectable		 1sqnB-3adrA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 154
VAL A 203
LEU A 161
 None
 0.70A 1yajG-3adrA:
undetectable		 1yajG-3adrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 5 PRO A  13
VAL A  38
ASN A  40
ILE A  19
 None
 1.06A 1z2bC-3adrA:
undetectable		 1z2bC-3adrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 LEU A 105
HIS A 148
HIS A  58
THR A 179
THR A 178
 None
ZN  A 262 (-3.3A)
ZN  A 262 (-3.4A)
None
None
 1.38A 2dttD-3adrA:
undetectable
2dttE-3adrA:
undetectable		 2dttD-3adrA:
18.15
2dttE-3adrA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 HIS A  58
ALA A 169
ILE A 176
LEU A 105
ILE A 242
 ZN  A 262 (-3.4A)
None
None
None
None
 1.25A 2h42A-3adrA:
undetectable		 2h42A-3adrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 ASP A  62
HIS A  63
HIS A 148
ASP A 165
HIS A 207
 ZN  A 263 (-2.7A)
ZN  A 263 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 ( 2.5A)
ZN  A 263 (-3.3A)
 0.29A 2q0jB-3adrA:
22.3		 2q0jB-3adrA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 ASP A  62
HIS A  63
HIS A 148
ASP A 165
LEU A 105
 ZN  A 263 (-2.7A)
ZN  A 263 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 ( 2.5A)
None
 0.97A 2q0jB-3adrA:
22.3		 2q0jB-3adrA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 ASP A 165
HIS A 207
ASP A  62
HIS A  63
HIS A 151
 ZN  A 263 ( 2.5A)
ZN  A 263 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 263 (-3.4A)
None
 1.30A 2q0jB-3adrA:
22.3		 2q0jB-3adrA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 12 TYR A 188
HIS A 152
THR A  57
ILE A 183
LEU A  59
 None
 1.39A 3lcvB-3adrA:
undetectable		 3lcvB-3adrA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 6 GLN A 246
HIS A  60
HIS A  58
HIS A 148
 None
ZN  A 262 (-3.3A)
ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
 1.21A 3nvcA-3adrA:
undetectable		 3nvcA-3adrA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 PRO A 177
ILE A 231
VAL A 174
PHE A 171
VAL A 233
 None
 1.19A 3rf4A-3adrA:
undetectable
3rf4C-3adrA:
undetectable		 3rf4A-3adrA:
18.25
3rf4C-3adrA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 PRO A 177
ILE A 231
VAL A 174
PHE A 171
VAL A 233
 None
 1.18A 3rf4A-3adrA:
undetectable
3rf4B-3adrA:
undetectable		 3rf4A-3adrA:
18.25
3rf4B-3adrA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 PRO A 177
ILE A 231
VAL A 174
PHE A 171
VAL A 233
 None
 1.16A 3rf4B-3adrA:
undetectable
3rf4C-3adrA:
undetectable		 3rf4B-3adrA:
18.25
3rf4C-3adrA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 10 HIS A  58
HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.77A 4c1dB-3adrA:
16.4		 4c1dB-3adrA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 HIS A  58
HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.80A 4c1fA-3adrA:
7.5
4c1fB-3adrA:
16.8		 4c1fA-3adrA:
25.42
4c1fB-3adrA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 9 HIS A  58
HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.77A 4c1hA-3adrA:
18.0		 4c1hA-3adrA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 10 GLY A  65
ASP A  62
GLY A  37
HIS A  58
HIS A 207
 EDO  A 265 ( 4.3A)
ZN  A 263 (-2.7A)
None
ZN  A 262 (-3.4A)
ZN  A 263 (-3.3A)
 1.10A 4c5nB-3adrA:
undetectable		 4c5nB-3adrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 8 HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.75A 4exsB-3adrA:
16.6		 4exsB-3adrA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 6 LEU A 142
TYR A 144
LYS A  81
GLU A 128
 None
 1.06A 4f3tA-3adrA:
undetectable		 4f3tA-3adrA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 10 VAL A  78
LEU A  88
GLY A  37
ALA A  36
LEU A  56
 None
 1.03A 4ph9A-3adrA:
undetectable		 4ph9A-3adrA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 10 VAL A  78
LEU A  88
GLY A  37
ALA A  36
LEU A  56
 None
 1.03A 4ph9B-3adrA:
undetectable		 4ph9B-3adrA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A 142
TYR A 144
LYS A  81
GLU A 128
 None
 1.07A 4z4fA-3adrA:
undetectable		 4z4fA-3adrA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 6 LEU A 142
TYR A 144
LYS A  81
GLU A 128
 None
 1.06A 4z4gA-3adrA:
undetectable		 4z4gA-3adrA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 11 PHE A  45
ALA A  43
GLY A  12
LEU A  56
LEU A  67
 None
None
None
None
EDO  A 265 ( 4.4A)
 1.17A 4zmeA-3adrA:
undetectable		 4zmeA-3adrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 8 HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.78A 5a5zA-3adrA:
16.5		 5a5zA-3adrA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		6 / 11 HIS A  58
HIS A  60
ASP A  62
HIS A  63
HIS A 148
HIS A 207
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 263 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.31A 5ayaA-3adrA:
16.8		 5ayaA-3adrA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		6 / 11 HIS A  58
HIS A  60
ASP A  62
HIS A  63
HIS A 148
THR A 178
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 263 (-3.4A)
ZN  A 262 (-3.3A)
None
 0.81A 5ayaA-3adrA:
16.8		 5ayaA-3adrA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		5 / 10 HIS A  58
HIS A  60
HIS A  63
HIS A 148
ASP A 165
 ZN  A 262 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.4A)
ZN  A 262 (-3.3A)
ZN  A 263 ( 2.5A)
 0.31A 5nzwA-3adrA:
6.3		 5nzwA-3adrA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 5 TYR A 109
TYR A 112
GLY A 113
GLY A 114
 None
 1.06A 5x7pA-3adrA:
undetectable		 5x7pA-3adrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		4 / 8 HIS A  60
ASP A  62
HIS A 148
HIS A 207
 ZN  A 262 (-3.3A)
ZN  A 263 (-2.7A)
ZN  A 262 (-3.3A)
ZN  A 263 (-3.3A)
 0.82A 5zj8A-3adrA:
6.2		 5zj8A-3adrA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 257
LYS A 258
SER A 260
 None
 0.78A 6az3P-3adrA:
undetectable		 6az3P-3adrA:
18.14