SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 10 ALA A 243
MET A 334
LEU A 329
GLN A 304
PHE A 247
None
1.42A 1aqbA-3aeuA:
undetectable
1aqbA-3aeuA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_CUG2_0
(BETA-CARBONIC
ANHYDRASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 CYH A 112
PRO A 113
SER A 111
CYH A  51
SF4  A 425 (-2.4A)
SF4  A 425 (-4.5A)
None
SF4  A 425 (-2.5A)
1.25A 1ekjG-3aeuA:
4.2
1ekjH-3aeuA:
2.4
1ekjG-3aeuA:
20.51
1ekjH-3aeuA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 12 HIS A 330
PHE A 225
GLU A 154
LEU A 158
LEU A 221
None
1.31A 1mj2A-3aeuA:
undetectable
1mj2B-3aeuA:
undetectable
1mj2A-3aeuA:
14.11
1mj2B-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 9 GLU A 154
LEU A 158
LEU A 221
HIS A 330
PHE A 225
None
1.34A 1mjlA-3aeuA:
undetectable
1mjlB-3aeuA:
undetectable
1mjlA-3aeuA:
14.11
1mjlB-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 11 GLU A 154
LEU A 158
LEU A 221
HIS A 330
PHE A 225
None
1.32A 1mjqA-3aeuA:
undetectable
1mjqB-3aeuA:
undetectable
1mjqA-3aeuA:
14.11
1mjqB-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 11 HIS A 330
PHE A 225
GLU A 154
LEU A 158
LEU A 221
None
1.32A 1mjqA-3aeuA:
undetectable
1mjqB-3aeuA:
undetectable
1mjqA-3aeuA:
14.11
1mjqB-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 10 HIS A 330
PHE A 225
GLU A 154
LEU A 158
LEU A 221
None
1.31A 1mjqG-3aeuA:
undetectable
1mjqH-3aeuA:
undetectable
1mjqG-3aeuA:
14.11
1mjqH-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 11 GLU A 154
LEU A 158
LEU A 221
HIS A 330
PHE A 225
None
1.34A 1mjqI-3aeuA:
undetectable
1mjqJ-3aeuA:
undetectable
1mjqI-3aeuA:
14.11
1mjqJ-3aeuA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 12 GLY A  47
LEU A  74
ASP A  90
VAL A  93
LEU A 108
None
0.93A 1zq9B-3aeuA:
undetectable
1zq9B-3aeuA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 11 LEU A 108
LEU A 106
LEU A  96
LYS A  95
LEU A  44
None
1.10A 2ceoA-3aeuA:
undetectable
2ceoA-3aeuA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 ARG A 359
THR A 322
ALA A 346
PRO A 365
None
1.43A 2ql8A-3aeuA:
undetectable
2ql8B-3aeuA:
undetectable
2ql8A-3aeuA:
18.66
2ql8B-3aeuA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 9 LEU A 117
LEU A 121
ALA A  85
LEU A  89
ALA A  72
None
1.29A 2vcvE-3aeuA:
undetectable
2vcvE-3aeuA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 9 LEU A 117
LEU A 121
ALA A  85
LEU A  89
ALA A  72
None
1.29A 2vcvH-3aeuA:
undetectable
2vcvH-3aeuA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
3 / 3 GLU A 210
GLN A  39
ARG A  68
None
0.99A 2w3bB-3aeuA:
1.1
2w3bB-3aeuA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
1.01A 3abkP-3aeuA:
undetectable
3abkW-3aeuA:
undetectable
3abkP-3aeuA:
22.02
3abkW-3aeuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 7 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
1.01A 3asnP-3aeuA:
undetectable
3asnW-3aeuA:
undetectable
3asnP-3aeuA:
22.02
3asnW-3aeuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 7 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
1.00A 3asoP-3aeuA:
undetectable
3asoW-3aeuA:
undetectable
3asoP-3aeuA:
22.02
3asoW-3aeuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
3 / 3 LEU A 108
LEU A 121
ARG A 123
None
0.68A 3hcnB-3aeuA:
undetectable
3hcnB-3aeuA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
3 / 3 VAL A  46
SER A 114
LEU A 121
None
0.72A 3n8xA-3aeuA:
undetectable
3n8xA-3aeuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 LEU A 297
PRO A 365
LEU A 367
LEU A 378
None
1.00A 3q1eA-3aeuA:
undetectable
3q1eC-3aeuA:
undetectable
3q1eA-3aeuA:
15.44
3q1eC-3aeuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 LEU A 378
LEU A 297
PRO A 365
LEU A 367
None
1.01A 3q1eA-3aeuA:
undetectable
3q1eC-3aeuA:
undetectable
3q1eA-3aeuA:
15.44
3q1eC-3aeuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
0.98A 3wg7P-3aeuA:
undetectable
3wg7W-3aeuA:
undetectable
3wg7P-3aeuA:
22.02
3wg7W-3aeuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 4 LEU A 329
ALA A 325
ILE A 324
LYS A 331
None
1.41A 4eixA-3aeuA:
undetectable
4eixA-3aeuA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
3 / 3 ASP A 366
VAL A 369
ASN A 364
None
0.68A 4lmnA-3aeuA:
undetectable
4lmnA-3aeuA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 THR A 348
THR A 368
HIS A 360
LEU A 357
None
1.36A 4lvcA-3aeuA:
3.4
4lvcA-3aeuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 THR A 348
THR A 368
HIS A 360
LEU A 357
None
1.35A 4lvcC-3aeuA:
undetectable
4lvcC-3aeuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
3 / 3 GLU A 271
TYR A 399
GLU A 249
None
0.71A 4ryaA-3aeuA:
undetectable
4ryaA-3aeuA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 12 ALA A 310
LEU A 341
GLY A 231
THR A 229
LEU A 221
None
1.22A 5eshA-3aeuA:
undetectable
5eshA-3aeuA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 GLY A 153
PRO A 224
GLN A 304
THR A 148
None
1.13A 5h5fA-3aeuA:
undetectable
5h5fA-3aeuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
5 / 7 GLY A 145
GLY A  27
SER A  30
LEU A  55
GLU A 115
SF4  A 425 (-3.7A)
None
None
None
None
1.04A 5izfA-3aeuA:
undetectable
5izfA-3aeuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 PHE A 107
PHE A  42
LEU A 106
LEU A  28
None
None
None
SF4  A 425 (-4.1A)
1.09A 5veuH-3aeuA:
undetectable
5veuH-3aeuA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 6 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
1.01A 5x19P-3aeuA:
undetectable
5x19P-3aeuA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
1.01A 5x1bP-3aeuA:
undetectable
5x1bP-3aeuA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 7 LEU A  44
PHE A  69
PHE A  42
LEU A  96
None
0.97A 5x1fP-3aeuA:
undetectable
5x1fW-3aeuA:
undetectable
5x1fP-3aeuA:
22.02
5x1fW-3aeuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 7 VAL A 162
GLY A 231
LEU A 226
GLY A 177
None
0.79A 6eu9D-3aeuA:
undetectable
6eu9D-3aeuA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus)
4 / 5 THR A 348
THR A 368
HIS A 360
LEU A 357
None
1.32A 6gbnD-3aeuA:
undetectable
6gbnD-3aeuA:
21.47