SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3afg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_T_TRPT81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	GLY A 301 ALA A 292 THR A 358 SER A 251	None	0.88A	1c9sT-3afgA: 3.0 1c9sU-3afgA: 3.0	1c9sT-3afgA: 11.86 1c9sU-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBY_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.99A	1fbyA-3afgA: undetectable	1fbyA-3afgA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBY_B_9CRB1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.98A	1fbyB-3afgA: undetectable	1fbyB-3afgA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FK6_A_LNLA1201_1 (NON-SPECIFIC LIPID TRANSFER PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	LEU A 19 ALA A 85 LEU A 81 ILE A 40 ILE A 76	None	0.89A	1fk6A-3afgA: undetectable	1fk6A-3afgA: 11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.94A	1fm6A-3afgA: undetectable	1fm6A-3afgA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_L_TRPL81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	GLY A 301 ALA A 292 THR A 358 SER A 251	None	0.87A	1gtfL-3afgA: 3.0 1gtfM-3afgA: 3.0	1gtfL-3afgA: 11.86 1gtfM-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	GLY A 301 ALA A 292 THR A 358 SER A 251	None	0.86A	1gtfN-3afgA: 3.0 1gtfO-3afgA: 3.0	1gtfN-3afgA: 11.86 1gtfO-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_Q_TRPQ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	GLY A 181 HIS A 180 HIS A 183 ILE A 145 GLY A 357	None	1.13A	1gtfQ-3afgA: 3.0 1gtfR-3afgA: 3.0	1gtfQ-3afgA: 11.86 1gtfR-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_S_TRPS81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	GLY A 181 HIS A 180 HIS A 183 ILE A 145 GLY A 357	None	1.12A	1gtfS-3afgA: 3.0 1gtfT-3afgA: 3.0	1gtfS-3afgA: 11.86 1gtfT-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_T_TRPT81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	GLY A 181 HIS A 180 HIS A 183 ILE A 145 GLY A 357	None	1.13A	1gtnT-3afgA: 3.0 1gtnU-3afgA: 3.0	1gtnT-3afgA: 11.86 1gtnU-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K74_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.95A	1k74A-3afgA: undetectable	1k74A-3afgA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PHG_A_MYTA422_1 (CYTOCHROME P450-CAM)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	THR A 310 GLY A 279 THR A 358 VAL A 328 ILE A 309	None	1.17A	1phgA-3afgA: undetectable	1phgA-3afgA: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RJD_A_SAMA801_1 (CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 6	ASP A 176 TYR A 175 ASP A 166 ASN A 169	None	1.31A	1rjdA-3afgA: undetectable	1rjdA-3afgA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RJD_B_SAMB802_1 (CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 6	ASP A 176 TYR A 175 ASP A 166 ASN A 169	None	1.30A	1rjdB-3afgA: 2.2	1rjdB-3afgA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RJD_C_SAMC803_1 (CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 6	ASP A 176 TYR A 175 ASP A 166 ASN A 169	None	1.32A	1rjdC-3afgA: 2.0	1rjdC-3afgA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_A_SAMA301_1 (HEMK PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 4	THR A 353 GLY A 181 ASP A 147 ALA A 359	None	0.99A	1sg9A-3afgA: 2.0	1sg9A-3afgA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_Q_TRPQ81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	GLY A 181 HIS A 180 HIS A 183 ALA A 188 ILE A 145	None	1.35A	1utdQ-3afgA: 2.9 1utdR-3afgA: 3.0	1utdQ-3afgA: 11.86 1utdR-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_S_TRPS81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	GLY A 181 HIS A 180 HIS A 183 ILE A 145 GLY A 357	None	1.14A	1utdS-3afgA: 3.0 1utdT-3afgA: 3.0	1utdS-3afgA: 11.86 1utdT-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_C_ADNC2502_2 (ADENOSYLHOMOCYSTEINA SE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	GLU A 390 THR A 391 LEU A 372	None	0.72A	1v8bC-3afgA: 3.7	1v8bC-3afgA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.98A	1xdkE-3afgA: undetectable	1xdkE-3afgA: 17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_A_9CRA201_1 (RXR-LIKE PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.92A	1xiuA-3afgA: undetectable	1xiuA-3afgA: 16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_A_9CRA801_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.94A	1xlsA-3afgA: undetectable	1xlsA-3afgA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_B_9CRB802_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.95A	1xlsB-3afgA: undetectable	1xlsB-3afgA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_C_9CRC803_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.95A	1xlsC-3afgA: undetectable	1xlsC-3afgA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_D_9CRD804_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.94A	1xlsD-3afgA: undetectable	1xlsD-3afgA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOU_A_CQAA403_0 (HISTAMINE N-METHYLTRANSFERASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	ASP A 398 LYS A 396 GLY A 408 THR A 451	None	1.03A	2aouA-3afgA: undetectable	2aouA-3afgA: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_D_SAMD301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	LYS A 414 ASP A 398 ASP A 393	None	0.97A	2br4D-3afgA: undetectable	2br4D-3afgA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_A_SAMA301_0 (YCGJ)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	6 / 12	GLY A 190 GLY A 192 ASP A 156 ALA A 337 THR A 182 ALA A 185	None	1.28A	2gluA-3afgA: undetectable	2gluA-3afgA: 17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VJ1_A_BEZA1303_0 (SARS CORONAVIRUS MAIN PROTEINASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	HIS A 180 MET A 344 MET A 360	None	0.92A	2vj1A-3afgA: undetectable	2vj1A-3afgA: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_A_ACHA1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	SER A 261 GLN A 252 ILE A 222 SER A 254	None	1.24A	2xz5A-3afgA: undetectable 2xz5B-3afgA: undetectable	2xz5A-3afgA: 17.13 2xz5B-3afgA: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM9_A_ACAA502_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	MET A 202 ALA A 203 GLY A 367 ILE A 368	None	0.81A	2zm9A-3afgA: undetectable	2zm9A-3afgA: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DHIC8_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	SER A 515 GLY A 446 GLY A 444	None	0.40A	3bogA-3afgA: undetectable 3bogC-3afgA: undetectable	3bogA-3afgA: undetectable 3bogC-3afgA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FAL_C_REAC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.98A	3falC-3afgA: undetectable	3falC-3afgA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FC6_A_REAA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	6 / 11	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387 ILE A 143	None	1.22A	3fc6A-3afgA: undetectable	3fc6A-3afgA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	GLY A 181 GLY A 149 LYS A 212 ALA A 359 ALA A 339	None	1.02A	3g89A-3afgA: undetectable	3g89A-3afgA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	GLY A 181 GLY A 149 LYS A 212 ALA A 359 ALA A 339	None	0.98A	3g8bA-3afgA: undetectable	3g8bA-3afgA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	GLY A 181 GLY A 149 LYS A 212 ALA A 359 ALA A 339	None	0.91A	3g8bB-3afgA: undetectable	3g8bB-3afgA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OAP_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	6 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387 ILE A 143	None	1.25A	3oapA-3afgA: undetectable	3oapA-3afgA: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9C_A_ECLA451_1 (CYTOCHROME P450 164A2)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	ALA A 206 LEU A 208 ILE A 145 VAL A 229 VAL A 233	None	1.44A	3r9cA-3afgA: undetectable	3r9cA-3afgA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCB_A_017A201_1 (PROTEASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	6 / 12	GLY A 271 ALA A 270 ASP A 269 ASN A 266 ILE A 68 VAL A 233	None	1.31A	3ucbA-3afgA: undetectable	3ucbA-3afgA: 13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CD2_A_FOLA207_0 (DIHYDROFOLATE REDUCTASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 187 ALA A 366 ILE A 145 LEU A 157 THR A 362	None	1.27A	4cd2A-3afgA: undetectable	4cd2A-3afgA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DT8_A_ADNA401_1 (APH(2'')-ID)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	SER A 515 ALA A 445 ILE A 442 PRO A 468 LEU A 465	None	1.01A	4dt8A-3afgA: undetectable	4dt8A-3afgA: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DT8_B_ADNB401_1 (APH(2'')-ID)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	SER A 515 ALA A 445 ILE A 442 PRO A 468 LEU A 465	None	0.94A	4dt8B-3afgA: undetectable	4dt8B-3afgA: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EIL_D_FOLD703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	VAL A 501 ASP A 460 SER A 476 PHE A 483 VAL A 500	None CA A 540 (-3.0A) None None None	1.46A	4eilD-3afgA: undetectable	4eilD-3afgA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQ4_A_SALA601_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	ARG A 322 THR A 299 THR A 318 GLY A 316	None	0.95A	4eq4A-3afgA: undetectable	4eq4A-3afgA: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQL_A_SALA602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	ARG A 322 THR A 299 THR A 318 GLY A 316	None	0.95A	4eqlA-3afgA: undetectable	4eqlA-3afgA: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQL_B_SALB602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	ARG A 322 THR A 299 THR A 318 GLY A 316	None	0.96A	4eqlB-3afgA: undetectable	4eqlB-3afgA: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYR_B_RITB301_1 (HIV-1 PROTEASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	ALA A 404 VAL A 303 ILE A 389 THR A 358	None	0.83A	4eyrA-3afgA: undetectable	4eyrA-3afgA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	ILE A 146 PRO A 381 VAL A 297 TRP A 268	None	1.01A	4f4dB-3afgA: 3.0	4f4dB-3afgA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFX_A_ACTA404_0 (THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 5	SER A 502 LYS A 433 LEU A 461 ASP A 460	None None None CA A 540 (-3.0A)	1.26A	4ifxA-3afgA: undetectable	4ifxA-3afgA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG1_A_ACTA504_0 (FAD:PROTEIN FMN TRANSFERASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 5	SER A 502 LYS A 433 LEU A 461 ASP A 460	None None None CA A 540 (-3.0A)	1.26A	4ig1A-3afgA: undetectable	4ig1A-3afgA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K6I_A_9RAA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ALA A 415 ALA A 416 LEU A 388 ALA A 387 VAL A 243	None	0.81A	4k6iA-3afgA: undetectable	4k6iA-3afgA: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K6I_A_9RAA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 416 LEU A 388 ALA A 387 VAL A 243	None	1.01A	4k6iA-3afgA: undetectable	4k6iA-3afgA: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_B_FOLB703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	VAL A 501 ASP A 460 SER A 476 PHE A 483 VAL A 500	None CA A 540 (-3.0A) None None None	1.41A	4kyaB-3afgA: undetectable	4kyaB-3afgA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_D_FOLD703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	VAL A 501 ASP A 460 SER A 476 PHE A 483 VAL A 500	None CA A 540 (-3.0A) None None None	1.42A	4kyaD-3afgA: undetectable	4kyaD-3afgA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_H_FOLH703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	VAL A 501 ASP A 460 SER A 476 PHE A 483 VAL A 500	None CA A 540 (-3.0A) None None None	1.39A	4kyaH-3afgA: undetectable	4kyaH-3afgA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_A_SAMA602_1 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	ASP A 230 ASN A 266 SER A 223	None	0.73A	4obwA-3afgA: 2.1	4obwA-3afgA: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_A_15UA301_1 (THROMBIN HEAVY CHAIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	HIS A 180 LEU A 214 ALA A 278 ALA A 359 GLY A 249	None	1.36A	4rn6A-3afgA: undetectable	4rn6A-3afgA: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_A_15UA301_1 (THROMBIN HEAVY CHAIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 10	HIS A 180 LEU A 214 ALA A 292 ALA A 359 GLY A 249	None	1.36A	4rn6A-3afgA: undetectable	4rn6A-3afgA: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA406_0 (FAD:PROTEIN FMN TRANSFERASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 5	SER A 502 LYS A 433 LEU A 461 ASP A 460	None None None CA A 540 (-3.0A)	1.27A	4xdtA-3afgA: undetectable	4xdtA-3afgA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YMG_B_SAMB1001_0 (PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	TYR A 351 SER A 195 SER A 153 ALA A 185 ALA A 337	None	1.36A	4ymgB-3afgA: 2.1	4ymgB-3afgA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BOJ_B_4TXB201_1 (TRANSTHYRETIN)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	LEU A 248 THR A 299 ALA A 277 THR A 358	None	1.04A	5bojB-3afgA: undetectable	5bojB-3afgA: 11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_B_SAMB601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	6 / 12	GLY A 256 ASP A 258 LEU A 260 SER A 259 VAL A 297 VAL A 276	None	1.31A	5dpdB-3afgA: undetectable	5dpdB-3afgA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	ALA A 277 GLY A 249 SER A 251 GLY A 289	None	0.71A	5e26A-3afgA: undetectable 5e26B-3afgA: undetectable	5e26A-3afgA: 21.60 5e26B-3afgA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_C_PAUC602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	GLY A 249 SER A 251 GLY A 289 ALA A 277	None	0.77A	5e26C-3afgA: undetectable 5e26D-3afgA: undetectable	5e26C-3afgA: 21.60 5e26D-3afgA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	SER A 251 GLY A 301 ALA A 292 THR A 358	None	0.86A	5eezL-3afgA: 3.0 5eezV-3afgA: 3.0	5eezL-3afgA: 11.86 5eezV-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	SER A 251 GLY A 301 ALA A 292 THR A 358	None	0.86A	5ef1L-3afgA: 2.9 5ef1V-3afgA: 3.0	5ef1L-3afgA: 11.86 5ef1V-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 8	SER A 251 GLY A 301 ALA A 292 THR A 358	None	0.86A	5ef2L-3afgA: 2.9 5ef2V-3afgA: 3.0	5ef2L-3afgA: 11.86 5ef2V-3afgA: 11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESK_A_1YNA701_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 4	ALA A 337 PRO A 363 LEU A 248 HIS A 180	None	1.21A	5eskA-3afgA: undetectable	5eskA-3afgA: 20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZF_E_AZ1E2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 6J9-ZEU-DAR-ACA-DAR- NH2)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 7	GLY A 190 GLY A 205 SER A 139 LEU A 371	None	0.70A	5izfA-3afgA: undetectable	5izfA-3afgA: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_N_BO2N304_1 (PROTEASOME SUBUNIT BETA TYPE-6)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	THR A 362 GLY A 357 ALA A 302 THR A 310 SER A 247	None	1.32A	5lf3N-3afgA: undetectable	5lf3N-3afgA: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_A_9CRA503_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.96A	5uanA-3afgA: undetectable	5uanA-3afgA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA502_2 (CYTOCHROME P450 2C9)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	3 / 3	LEU A 272 VAL A 229 ASP A 230	None	0.61A	5x23A-3afgA: undetectable	5x23A-3afgA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.90A	5z12B-3afgA: undetectable	5z12B-3afgA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_C_9CRC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.92A	5z12C-3afgA: undetectable	5z12C-3afgA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Y_D_9CRD501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.92A	6a5yD-3afgA: undetectable	6a5yD-3afgA: 9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Z_L_9CRL501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 12	ILE A 368 ALA A 415 ALA A 416 LEU A 388 ALA A 387	None	0.96A	6a5zL-3afgA: undetectable	6a5zL-3afgA: 9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_I_EY4I500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	4 / 5	GLN A 125 VAL A 126 TRP A 333 THR A 353	None	1.48A	6cduI-3afgA: undetectable 6cduJ-3afgA: undetectable	6cduI-3afgA: 22.27 6cduJ-3afgA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DK1_C_GM4C301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	3afg	SUBTILISIN-LIKE SERINE PROTEASE (Thermococcus kodakarensis)	5 / 11	VAL A 243 ALA A 369 TRP A 268 THR A 362 ALA A 366	None	1.18A	6dk1C-3afgA: undetectable	6dk1C-3afgA: 17.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C9S_T_TRPT81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLY A 301;ALA A 292;THR A 358;SER A 251","None","0.88A","1c9sT-3afgA:3.0;1c9sU-3afgA:3.0","1c9sT-3afgA:11.86;1c9sU-3afgA:11.86"],["1FBY_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.99A","1fbyA-3afgA:undetectable","1fbyA-3afgA:17.04"],["1FBY_B_9CRB1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.98A","1fbyB-3afgA:undetectable","1fbyB-3afgA:17.04"],["1FK6_A_LNLA1201_1","NON-SPECIFIC LIPID TRANSFER PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"LEU A  19;ALA A  85;LEU A  81;ILE A  40;ILE A  76","None","0.89A","1fk6A-3afgA:undetectable","1fk6A-3afgA:11.63"],["1FM6_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.94A","1fm6A-3afgA:undetectable","1fm6A-3afgA:17.04"],["1GTF_L_TRPL81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLY A 301;ALA A 292;THR A 358;SER A 251","None","0.87A","1gtfL-3afgA:3.0;1gtfM-3afgA:3.0","1gtfL-3afgA:11.86;1gtfM-3afgA:11.86"],["1GTF_N_TRPN81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLY A 301;ALA A 292;THR A 358;SER A 251","None","0.86A","1gtfN-3afgA:3.0;1gtfO-3afgA:3.0","1gtfN-3afgA:11.86;1gtfO-3afgA:11.86"],["1GTF_Q_TRPQ81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;HIS A 180;HIS A 183;ILE A 145;GLY A 357","None","1.13A","1gtfQ-3afgA:3.0;1gtfR-3afgA:3.0","1gtfQ-3afgA:11.86;1gtfR-3afgA:11.86"],["1GTF_S_TRPS81_0","TRP RNA-BINDING ATTENUATION PROTEIN (TRAP)","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;HIS A 180;HIS A 183;ILE A 145;GLY A 357","None","1.12A","1gtfS-3afgA:3.0;1gtfT-3afgA:3.0","1gtfS-3afgA:11.86;1gtfT-3afgA:11.86"],["1GTN_T_TRPT81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;HIS A 180;HIS A 183;ILE A 145;GLY A 357","None","1.13A","1gtnT-3afgA:3.0;1gtnU-3afgA:3.0","1gtnT-3afgA:11.86;1gtnU-3afgA:11.86"],["1K74_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.95A","1k74A-3afgA:undetectable","1k74A-3afgA:17.04"],["1PHG_A_MYTA422_1","CYTOCHROME P450-CAM","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"THR A 310;GLY A 279;THR A 358;VAL A 328;ILE A 309","None","1.17A","1phgA-3afgA:undetectable","1phgA-3afgA:19.08"],["1RJD_A_SAMA801_1","CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ASP A 176;TYR A 175;ASP A 166;ASN A 169","None","1.31A","1rjdA-3afgA:undetectable","1rjdA-3afgA:20.84"],["1RJD_B_SAMB802_1","CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ASP A 176;TYR A 175;ASP A 166;ASN A 169","None","1.30A","1rjdB-3afgA:2.2","1rjdB-3afgA:20.84"],["1RJD_C_SAMC803_1","CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ASP A 176;TYR A 175;ASP A 166;ASN A 169","None","1.32A","1rjdC-3afgA:2.0","1rjdC-3afgA:20.84"],["1SG9_A_SAMA301_1","HEMK PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"THR A 353;GLY A 181;ASP A 147;ALA A 359","None","0.99A","1sg9A-3afgA:2.0","1sg9A-3afgA:18.98"],["1UTD_Q_TRPQ81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;HIS A 180;HIS A 183;ALA A 188;ILE A 145","None","1.35A","1utdQ-3afgA:2.9;1utdR-3afgA:3.0","1utdQ-3afgA:11.86;1utdR-3afgA:11.86"],["1UTD_S_TRPS81_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;HIS A 180;HIS A 183;ILE A 145;GLY A 357","None","1.14A","1utdS-3afgA:3.0;1utdT-3afgA:3.0","1utdS-3afgA:11.86;1utdT-3afgA:11.86"],["1V8B_C_ADNC2502_2","ADENOSYLHOMOCYSTEINASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"GLU A 390;THR A 391;LEU A 372","None","0.72A","1v8bC-3afgA:3.7","1v8bC-3afgA:22.08"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.98A","1xdkE-3afgA:undetectable","1xdkE-3afgA:17.41"],["1XIU_A_9CRA201_1","RXR-LIKE PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.92A","1xiuA-3afgA:undetectable","1xiuA-3afgA:16.33"],["1XLS_A_9CRA801_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.94A","1xlsA-3afgA:undetectable","1xlsA-3afgA:16.82"],["1XLS_B_9CRB802_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.95A","1xlsB-3afgA:undetectable","1xlsB-3afgA:16.82"],["1XLS_C_9CRC803_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.95A","1xlsC-3afgA:undetectable","1xlsC-3afgA:16.82"],["1XLS_D_9CRD804_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.94A","1xlsD-3afgA:undetectable","1xlsD-3afgA:16.82"],["2AOU_A_CQAA403_0","HISTAMINE N-METHYLTRANSFERASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ASP A 398;LYS A 396;GLY A 408;THR A 451","None","1.03A","2aouA-3afgA:undetectable","2aouA-3afgA:20.15"],["2BR4_D_SAMD301_1","CEPHALOSPORIN HYDROXYLASE CMCI","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"LYS A 414;ASP A 398;ASP A 393","None","0.97A","2br4D-3afgA:undetectable","2br4D-3afgA:15.98"],["2GLU_A_SAMA301_0","YCGJ","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",6,"GLY A 190;GLY A 192;ASP A 156;ALA A 337;THR A 182;ALA A 185","None","1.28A","2gluA-3afgA:undetectable","2gluA-3afgA:17.60"],["2VJ1_A_BEZA1303_0","SARS CORONAVIRUS MAIN PROTEINASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"HIS A 180;MET A 344;MET A 360","None","0.92A","2vj1A-3afgA:undetectable","2vj1A-3afgA:19.82"],["2XZ5_A_ACHA1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 261;GLN A 252;ILE A 222;SER A 254","None","1.24A","2xz5A-3afgA:undetectable;2xz5B-3afgA:undetectable","2xz5A-3afgA:17.13;2xz5B-3afgA:17.13"],["2ZM9_A_ACAA502_1","6-AMINOHEXANOATE-DIMER HYDROLASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"MET A 202;ALA A 203;GLY A 367;ILE A 368","None","0.81A","2zm9A-3afgA:undetectable","2zm9A-3afgA:19.78"],["3BOG_C_DHIC8_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"SER A 515;GLY A 446;GLY A 444","None","0.40A","3bogA-3afgA:undetectable;3bogC-3afgA:undetectable","3bogA-3afgA:undetectable;3bogC-3afgA:undetectable"],["3FAL_C_REAC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.98A","3falC-3afgA:undetectable","3falC-3afgA:17.22"],["3FC6_A_REAA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",6,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387;ILE A 143","None","1.22A","3fc6A-3afgA:undetectable","3fc6A-3afgA:17.22"],["3G89_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;GLY A 149;LYS A 212;ALA A 359;ALA A 339","None","1.02A","3g89A-3afgA:undetectable","3g89A-3afgA:18.52"],["3G8B_A_SAMA303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;GLY A 149;LYS A 212;ALA A 359;ALA A 339","None","0.98A","3g8bA-3afgA:undetectable","3g8bA-3afgA:18.52"],["3G8B_B_SAMB303_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"GLY A 181;GLY A 149;LYS A 212;ALA A 359;ALA A 339","None","0.91A","3g8bB-3afgA:undetectable","3g8bB-3afgA:18.52"],["3OAP_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",6,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387;ILE A 143","None","1.25A","3oapA-3afgA:undetectable","3oapA-3afgA:16.64"],["3R9C_A_ECLA451_1","CYTOCHROME P450 164A2","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ALA A 206;LEU A 208;ILE A 145;VAL A 229;VAL A 233","None","1.44A","3r9cA-3afgA:undetectable","3r9cA-3afgA:19.06"],["3UCB_A_017A201_1","PROTEASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",6,"GLY A 271;ALA A 270;ASP A 269;ASN A 266;ILE A  68;VAL A 233","None","1.31A","3ucbA-3afgA:undetectable","3ucbA-3afgA:13.28"],["4CD2_A_FOLA207_0","DIHYDROFOLATE REDUCTASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 187;ALA A 366;ILE A 145;LEU A 157;THR A 362","None","1.27A","4cd2A-3afgA:undetectable","4cd2A-3afgA:16.03"],["4DT8_A_ADNA401_1","APH(2'')-ID","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"SER A 515;ALA A 445;ILE A 442;PRO A 468;LEU A 465","None","1.01A","4dt8A-3afgA:undetectable","4dt8A-3afgA:19.89"],["4DT8_B_ADNB401_1","APH(2'')-ID","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"SER A 515;ALA A 445;ILE A 442;PRO A 468;LEU A 465","None","0.94A","4dt8B-3afgA:undetectable","4dt8B-3afgA:19.89"],["4EIL_D_FOLD703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"VAL A 501;ASP A 460;SER A 476;PHE A 483;VAL A 500","None; CA A 540 (-3.0A);None;None;None","1.46A","4eilD-3afgA:undetectable","4eilD-3afgA:21.64"],["4EQ4_A_SALA601_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ARG A 322;THR A 299;THR A 318;GLY A 316","None","0.95A","4eq4A-3afgA:undetectable","4eq4A-3afgA:22.61"],["4EQL_A_SALA602_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ARG A 322;THR A 299;THR A 318;GLY A 316","None","0.95A","4eqlA-3afgA:undetectable","4eqlA-3afgA:22.61"],["4EQL_B_SALB602_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ARG A 322;THR A 299;THR A 318;GLY A 316","None","0.96A","4eqlB-3afgA:undetectable","4eqlB-3afgA:22.61"],["4EYR_B_RITB301_1","HIV-1 PROTEASE;HIV-1 PROTEASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ALA A 404;VAL A 303;ILE A 389;THR A 358","None","0.83A","4eyrA-3afgA:undetectable","4eyrA-3afgA:12.86"],["4F4D_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ILE A 146;PRO A 381;VAL A 297;TRP A 268","None","1.01A","4f4dB-3afgA:3.0","4f4dB-3afgA:19.06"],["4IFX_A_ACTA404_0","THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 502;LYS A 433;LEU A 461;ASP A 460","None;None;None; CA A 540 (-3.0A)","1.26A","4ifxA-3afgA:undetectable","4ifxA-3afgA:21.21"],["4IG1_A_ACTA504_0","FAD:PROTEIN FMN TRANSFERASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 502;LYS A 433;LEU A 461;ASP A 460","None;None;None; CA A 540 (-3.0A)","1.26A","4ig1A-3afgA:undetectable","4ig1A-3afgA:21.21"],["4K6I_A_9RAA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ALA A 415;ALA A 416;LEU A 388;ALA A 387;VAL A 243","None","0.81A","4k6iA-3afgA:undetectable","4k6iA-3afgA:16.64"],["4K6I_A_9RAA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 416;LEU A 388;ALA A 387;VAL A 243","None","1.01A","4k6iA-3afgA:undetectable","4k6iA-3afgA:16.64"],["4KYA_B_FOLB703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"VAL A 501;ASP A 460;SER A 476;PHE A 483;VAL A 500","None; CA A 540 (-3.0A);None;None;None","1.41A","4kyaB-3afgA:undetectable","4kyaB-3afgA:21.64"],["4KYA_D_FOLD703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"VAL A 501;ASP A 460;SER A 476;PHE A 483;VAL A 500","None; CA A 540 (-3.0A);None;None;None","1.42A","4kyaD-3afgA:undetectable","4kyaD-3afgA:21.64"],["4KYA_H_FOLH703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"VAL A 501;ASP A 460;SER A 476;PHE A 483;VAL A 500","None; CA A 540 (-3.0A);None;None;None","1.39A","4kyaH-3afgA:undetectable","4kyaH-3afgA:21.64"],["4OBW_A_SAMA602_1","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"ASP A 230;ASN A 266;SER A 223","None","0.73A","4obwA-3afgA:2.1","4obwA-3afgA:18.36"],["4RN6_A_15UA301_1","THROMBIN HEAVY CHAIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"HIS A 180;LEU A 214;ALA A 278;ALA A 359;GLY A 249","None","1.36A","4rn6A-3afgA:undetectable","4rn6A-3afgA:18.01"],["4RN6_A_15UA301_1","THROMBIN HEAVY CHAIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"HIS A 180;LEU A 214;ALA A 292;ALA A 359;GLY A 249","None","1.36A","4rn6A-3afgA:undetectable","4rn6A-3afgA:18.01"],["4XDT_A_ACTA406_0","FAD:PROTEIN FMN TRANSFERASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 502;LYS A 433;LEU A 461;ASP A 460","None;None;None; CA A 540 (-3.0A)","1.27A","4xdtA-3afgA:undetectable","4xdtA-3afgA:20.62"],["4YMG_B_SAMB1001_0","PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"TYR A 351;SER A 195;SER A 153;ALA A 185;ALA A 337","None","1.36A","4ymgB-3afgA:2.1","4ymgB-3afgA:19.01"],["5BOJ_B_4TXB201_1","TRANSTHYRETIN","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"LEU A 248;THR A 299;ALA A 277;THR A 358","None","1.04A","5bojB-3afgA:undetectable","5bojB-3afgA:11.69"],["5DPD_B_SAMB601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",6,"GLY A 256;ASP A 258;LEU A 260;SER A 259;VAL A 297;VAL A 276","None","1.31A","5dpdB-3afgA:undetectable","5dpdB-3afgA:20.85"],["5E26_B_PAUB601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ALA A 277;GLY A 249;SER A 251;GLY A 289","None","0.71A","5e26A-3afgA:undetectable;5e26B-3afgA:undetectable","5e26A-3afgA:21.60;5e26B-3afgA:21.60"],["5E26_C_PAUC602_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLY A 249;SER A 251;GLY A 289;ALA A 277","None","0.77A","5e26C-3afgA:undetectable;5e26D-3afgA:undetectable","5e26C-3afgA:21.60;5e26D-3afgA:21.60"],["5EEZ_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 251;GLY A 301;ALA A 292;THR A 358","None","0.86A","5eezL-3afgA:3.0;5eezV-3afgA:3.0","5eezL-3afgA:11.86;5eezV-3afgA:11.86"],["5EF1_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 251;GLY A 301;ALA A 292;THR A 358","None","0.86A","5ef1L-3afgA:2.9;5ef1V-3afgA:3.0","5ef1L-3afgA:11.86;5ef1V-3afgA:11.86"],["5EF2_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"SER A 251;GLY A 301;ALA A 292;THR A 358","None","0.86A","5ef2L-3afgA:2.9;5ef2V-3afgA:3.0","5ef2L-3afgA:11.86;5ef2V-3afgA:11.86"],["5ESK_A_1YNA701_2","LANOSTEROL 14-ALPHA DEMETHYLASE","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"ALA A 337;PRO A 363;LEU A 248;HIS A 180","None","1.21A","5eskA-3afgA:undetectable","5eskA-3afgA:20.57"],["5IZF_E_AZ1E2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;6J9-ZEU-DAR-ACA-DAR-NH2","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLY A 190;GLY A 205;SER A 139;LEU A 371","None","0.70A","5izfA-3afgA:undetectable","5izfA-3afgA:21.08"],["5LF3_N_BO2N304_1","PROTEASOME SUBUNIT BETA TYPE-6","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"THR A 362;GLY A 357;ALA A 302;THR A 310;SER A 247","None","1.32A","5lf3N-3afgA:undetectable","5lf3N-3afgA:15.94"],["5UAN_A_9CRA503_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.96A","5uanA-3afgA:undetectable","5uanA-3afgA:19.75"],["5X23_A_LSNA502_2","CYTOCHROME P450 2C9","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",3,"LEU A 272;VAL A 229;ASP A 230","None","0.61A","5x23A-3afgA:undetectable","5x23A-3afgA:21.58"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.90A","5z12B-3afgA:undetectable","5z12B-3afgA:8.70"],["5Z12_C_9CRC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.92A","5z12C-3afgA:undetectable","5z12C-3afgA:8.70"],["6A5Y_D_9CRD501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.92A","6a5yD-3afgA:undetectable","6a5yD-3afgA:9.09"],["6A5Z_L_9CRL501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"ILE A 368;ALA A 415;ALA A 416;LEU A 388;ALA A 387","None","0.96A","6a5zL-3afgA:undetectable","6a5zL-3afgA:9.09"],["6CDU_I_EY4I500_0","CHIMERIC ALPHA1GABAA RECEPTOR","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",4,"GLN A 125;VAL A 126;TRP A 333;THR A 353","None","1.48A","6cduI-3afgA:undetectable;6cduJ-3afgA:undetectable","6cduI-3afgA:22.27;6cduJ-3afgA:22.27"],["6DK1_C_GM4C301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","3afg","SUBTILISIN-LIKE SERINE PROTEASE","Thermococcus kodakarensis",5,"VAL A 243;ALA A 369;TRP A 268;THR A 362;ALA A 366","None","1.18A","6dk1C-3afgA:undetectable","6dk1C-3afgA:17.67"]]