SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3agb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLU A 249
ILE A 227
LEU A 165
VAL A 204
 None
None
None
NA  A   1 (-4.7A)
 0.62A 1a29A-3agbA:
undetectable		 1a29A-3agbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLU A 231
SER A  59
GLU A 232
GLU A 236
 None
 1.10A 1knyA-3agbA:
undetectable
1knyB-3agbA:
undetectable		 1knyA-3agbA:
20.71
1knyB-3agbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 PHE A  52
VAL A 308
SER A 137
PHE A 141
LEU A  86
 None
 1.36A 1wrkA-3agbA:
undetectable
1wrkB-3agbA:
undetectable		 1wrkA-3agbA:
18.83
1wrkB-3agbA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LEU A  81
LEU A 142
VAL A 259
VAL A  73
 None
 0.87A 2bdmA-3agbA:
undetectable		 2bdmA-3agbA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 PHE A 151
LEU A  69
LEU A 155
LEU A 165
 None
 0.92A 2bfpB-3agbA:
undetectable		 2bfpB-3agbA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE A 135
SER A 137
ILE A 312
PHE A 296
 None
 1.13A 2q6hA-3agbA:
undetectable		 2q6hA-3agbA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ILE A 135
SER A 137
ILE A 312
PHE A 296
 None
 1.14A 2q72A-3agbA:
undetectable		 2q72A-3agbA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE A 135
SER A 137
ILE A 312
PHE A 296
 None
 1.15A 2qb4A-3agbA:
undetectable		 2qb4A-3agbA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 HIS A 194
ASP A 188
THR A 189
TYR A 186
 None
 1.30A 2y69A-3agbA:
undetectable
2y69C-3agbA:
2.3		 2y69A-3agbA:
19.45
2y69C-3agbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 HIS A 194
ASP A 188
THR A 189
TYR A 186
 None
 1.27A 2zxwA-3agbA:
undetectable
2zxwC-3agbA:
2.3		 2zxwA-3agbA:
19.45
2zxwC-3agbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 HIS A 194
ASP A 188
THR A 189
TYR A 186
 None
 1.30A 2zxwN-3agbA:
undetectable
2zxwP-3agbA:
1.8		 2zxwN-3agbA:
19.45
2zxwP-3agbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A  81
VAL A 118
PHE A 141
LEU A 251
VAL A  73
 None
 1.27A 3sp9B-3agbA:
undetectable		 3sp9B-3agbA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 SER A 209
TYR A 207
ASP A 291
 None
 0.85A 4rp8C-3agbA:
undetectable		 4rp8C-3agbA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 SER A 121
SER A 137
PHE A 296
 None
 0.71A 5mugA-3agbA:
undetectable		 5mugA-3agbA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 CYH A 125
MET A 299
ASN A  95
 None
 1.39A 5qh8A-3agbA:
undetectable		 5qh8A-3agbA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG A  91
LYS A  51
ARG A  62
 None
 1.13A 6c06D-3agbA:
undetectable		 6c06D-3agbA:
undetectable