SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3agf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 10 PHE A  70
PRO A 300
VAL A  68
ILE A 295
GLY A  50
 None
 1.45A 13gsA-3agfA:
undetectable		 13gsA-3agfA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 9 PHE A  70
PRO A 300
VAL A  68
ILE A 295
GLY A  50
 None
 1.45A 13gsB-3agfA:
undetectable		 13gsB-3agfA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		6 / 12 SER A  74
LYS A  77
ASN A 126
LYS A 268
SER A 269
GLY A 270
 None
 0.50A 1ghmA-3agfA:
4.2		 1ghmA-3agfA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 12 LEU A 324
MET A 318
CYH A  52
THR A 211
ILE A 214
 None
 1.45A 1p93B-3agfA:
undetectable		 1p93B-3agfA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 12 GLN A 204
LEU A 246
ILE A  82
ALA A 133
VAL A  93
 None
 1.03A 2g72B-3agfA:
undetectable		 2g72B-3agfA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 9 ALA A 240
ASP A 224
VAL A 234
GLY A 218
VAL A 151
 None
 0.96A 2q5kA-3agfA:
undetectable		 2q5kA-3agfA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 10 ILE A 220
ILE A 235
VAL A 239
PRO A 123
LEU A 278
 None
 1.23A 3elzC-3agfA:
undetectable		 3elzC-3agfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		4 / 6 ILE A 109
ILE A 132
GLY A 128
VAL A 194
 None
 0.99A 3n3iA-3agfA:
undetectable		 3n3iA-3agfA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 11 GLU A  23
GLY A  50
ALA A  63
ILE A 297
ASP A  65
 None
 1.20A 3nmuB-3agfA:
undetectable
3nmuJ-3agfA:
undetectable		 3nmuB-3agfA:
24.56
3nmuJ-3agfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 11 GLU A  23
TYR A  25
GLY A  50
ALA A  63
ASP A  65
 None
 1.23A 3nmuB-3agfA:
undetectable
3nmuJ-3agfA:
undetectable		 3nmuB-3agfA:
24.56
3nmuJ-3agfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		4 / 6 ASN A 254
GLY A 103
ASP A 104
ILE A 110
 None
 0.91A 3w9tF-3agfA:
undetectable		 3w9tF-3agfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 12 VAL A 234
ILE A 235
GLY A 218
ILE A 220
PRO A 281
 None
 1.02A 4q5mA-3agfA:
undetectable		 4q5mA-3agfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		3 / 3 GLY A 138
PRO A 137
ALA A  84
 None
 0.56A 4qn9B-3agfA:
undetectable		 4qn9B-3agfA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		4 / 7 LEU A 198
ALA A 133
ALA A 129
ALA A 181
 None
 0.65A 4z90F-3agfA:
undetectable
4z90G-3agfA:
undetectable
4z90H-3agfA:
undetectable
4z90J-3agfA:
undetectable		 4z90F-3agfA:
18.80
4z90G-3agfA:
18.80
4z90H-3agfA:
18.80
4z90J-3agfA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		5 / 7 GLY A  50
GLY A 299
PRO A 300
GLY A 273
GLY A 274
 None
 0.92A 6ag0A-3agfA:
undetectable		 6ag0A-3agfA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 3agf GLUTAMINASE 1
(Bacillus
subtilis) 		4 / 7 VAL A  78
LEU A 155
GLY A 218
GLY A 274
 None
 0.77A 6eu9D-3agfA:
undetectable		 6eu9D-3agfA:
11.96