SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ago'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		3 / 3 GLU A  62
HIS A  41
ASP A 108
 3AM  A 115 (-2.9A)
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
 0.68A 1i9gA-3agoA:
undetectable		 1i9gA-3agoA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 5 THR A 102
THR A 100
ASP A  84
TYR A  14
 None
 1.45A 4oltA-3agoA:
undetectable		 4oltA-3agoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 5 THR A 102
THR A 100
ASP A  84
TYR A  14
 None
 1.45A 4oltB-3agoA:
undetectable		 4oltB-3agoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 5 THR A 102
THR A 100
ASP A  84
TYR A  14
 None
 1.46A 4qwpA-3agoA:
undetectable		 4qwpA-3agoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		3 / 3 GLU A  62
HIS A  41
ASP A 108
 3AM  A 115 (-2.9A)
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
 0.49A 5c0oG-3agoA:
undetectable		 5c0oG-3agoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 6 VAL A  86
ASN A  16
PRO A   4
ILE A   3
 None
 1.25A 6h7uA-3agoA:
undetectable		 6h7uA-3agoA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 8 ASP A  84
HIS A  41
GLU A  62
GLU A  49
 None
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
3AM  A 115 (-2.8A)
 1.03A 6mn4A-3agoA:
undetectable		 6mn4A-3agoA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 8 ASP A  84
HIS A  41
GLU A  62
GLU A  49
 None
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
3AM  A 115 (-2.8A)
 1.11A 6mn4B-3agoA:
undetectable		 6mn4B-3agoA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ago RIBONUCLEASE U2
(Ustilago
sphaerogena) 		4 / 8 ASP A  84
HIS A  41
GLU A  62
GLU A  49
 None
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
3AM  A 115 (-2.8A)
 1.06A 6mn4D-3agoA:
undetectable		 6mn4D-3agoA:
16.86