SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ahx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		6 / 12 ALA A 190
ALA A 193
TRP A 134
ALA A 176
ILE A 219
HIS A 201
 None
 1.39A 1fm6U-3ahxA:
undetectable		 1fm6U-3ahxA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 12 PHE A  10
SER A  75
ARG A  77
ILE A 350
LEU A 439
 None
 1.26A 1kglA-3ahxA:
undetectable		 1kglA-3ahxA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 LEU A 150
PHE A 151
GLY A 155
ILE A 109
 None
 0.99A 2bdmA-3ahxA:
undetectable		 2bdmA-3ahxA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		3 / 3 TYR A  76
GLY A  13
PHE A 401
 None
 0.65A 2m2pB-3ahxA:
undetectable		 2m2pB-3ahxA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 6 LEU A 150
TYR A 146
ILE A  98
ILE A  80
 None
 0.89A 2q8hA-3ahxA:
undetectable		 2q8hA-3ahxA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 11 ASN A 165
GLU A 166
TYR A 296
GLU A 352
TRP A 399
 None
 0.81A 2v3dB-3ahxA:
2.8		 2v3dB-3ahxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 9 PHE A 281
PRO A 167
LEU A 221
ALA A 194
ALA A 253
 None
 1.30A 2vcvE-3ahxA:
0.5		 2vcvE-3ahxA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 9 PHE A 281
PRO A 167
LEU A 221
ALA A 194
ALA A 253
 None
 1.27A 2vcvH-3ahxA:
undetectable		 2vcvH-3ahxA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 ARG A   5
PHE A   6
PHE A  12
ILE A 387
 None
 1.09A 2zseA-3ahxA:
undetectable		 2zseA-3ahxA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 5 ILE A 293
PHE A   6
PHE A  12
TYR A 396
 None
 1.08A 3em0A-3ahxA:
undetectable		 3em0A-3ahxA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		3 / 3 GLU A 409
GLU A 406
TRP A 325
 None
 0.93A 3hrdA-3ahxA:
undetectable
3hrdE-3ahxA:
undetectable
3hrdF-3ahxA:
undetectable		 3hrdA-3ahxA:
21.36
3hrdE-3ahxA:
21.36
3hrdF-3ahxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 PRO A 392
ILE A 346
LEU A 255
ILE A 339
 None
 0.91A 3p50A-3ahxA:
undetectable		 3p50A-3ahxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 PRO A 392
ILE A 346
LEU A 255
ILE A 339
 None
 0.91A 3p50B-3ahxA:
undetectable		 3p50B-3ahxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 PRO A 392
ILE A 346
LEU A 255
ILE A 339
 None
 0.91A 3p50C-3ahxA:
undetectable		 3p50C-3ahxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 PRO A 392
ILE A 346
LEU A 255
ILE A 339
 None
 0.92A 3p50D-3ahxA:
undetectable		 3p50D-3ahxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 PRO A 392
ILE A 346
LEU A 255
ILE A 339
 None
 0.92A 3p50E-3ahxA:
undetectable		 3p50E-3ahxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 12 PHE A 100
LEU A 104
TYR A 101
ALA A 116
TYR A  76
 None
 1.01A 3vw7A-3ahxA:
undetectable		 3vw7A-3ahxA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 7 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.75A 4c5nA-3ahxA:
2.9		 4c5nA-3ahxA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 8 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.70A 4c5nC-3ahxA:
undetectable		 4c5nC-3ahxA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 12 ALA A  54
ALA A  46
GLY A 410
PHE A 405
TYR A 411
 None
 1.27A 4r29C-3ahxA:
undetectable		 4r29C-3ahxA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 9 ILE A  93
LEU A 104
LEU A 150
ILE A 117
PHE A  86
 None
 1.32A 4r38C-3ahxA:
undetectable		 4r38C-3ahxA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 8 GLY A 244
TYR A 343
ASP A 342
ARG A 341
 None
 1.05A 5gqbA-3ahxA:
13.1		 5gqbA-3ahxA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 12 ILE A 184
TYR A 175
GLU A  32
ALA A 170
SER A  39
 None
 1.23A 5igvA-3ahxA:
undetectable		 5igvA-3ahxA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 12 ILE A 398
GLY A 354
TYR A 396
GLU A 438
ALA A 383
 None
 1.24A 5igvA-3ahxA:
undetectable		 5igvA-3ahxA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		4 / 5 GLY A 365
ASN A 362
ASP A 364
ARG A 363
 None
 1.40A 6dwdB-3ahxA:
undetectable
6dwdD-3ahxA:
undetectable		 6dwdB-3ahxA:
21.33
6dwdD-3ahxA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 10 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
 None
 1.07A 6ebpD-3ahxA:
undetectable		 6ebpD-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 11 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
 None
 1.07A 6ebzA-3ahxA:
undetectable		 6ebzA-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 11 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
 None
 1.05A 6ebzB-3ahxA:
undetectable		 6ebzB-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 11 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
 None
 1.06A 6ebzC-3ahxA:
undetectable		 6ebzC-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		5 / 11 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
 None
 1.08A 6ebzD-3ahxA:
undetectable		 6ebzD-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 3ahx BETA-GLUCOSIDASE A
(Clostridium
cellulovorans) 		3 / 3 TYR A  61
HIS A  57
PHE A 100
 None
 0.99A 6esmA-3ahxA:
undetectable		 6esmA-3ahxA:
13.12