SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ail'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 GLY A 285
ILE A 238
TYR A 177
GLY A 274
 None
 0.78A 11gsB-3ailA:
undetectable		 11gsB-3ailA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACL_A_DMEA999_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 10 SER A 150
TRP A 205
PHE A 197
HIS A 273
GLY A 274
 DEP  A 304 (-1.5A)
None
None
DEP  A 304 (-4.1A)
None
 1.33A 1aclA-3ailA:
18.5		 1aclA-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 8 GLY A  79
SER A 150
PHE A 197
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-1.5A)
None
DEP  A 304 (-4.1A)
 0.86A 1ax9A-3ailA:
18.1		 1ax9A-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ASN A 254
ALA A 251
GLY A 249
TYR A 252
 None
 1.14A 1c8lA-3ailA:
5.5		 1c8lA-3ailA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 197
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
None
DEP  A 304 (-4.1A)
 0.47A 1dx6A-3ailA:
18.7		 1dx6A-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.98A 1dx6A-3ailA:
18.7		 1dx6A-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.10A 1dz4A-3ailA:
undetectable		 1dz4A-3ailA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ASN A 254
ALA A 251
GLY A 249
TYR A 252
 None
 1.11A 1gfzA-3ailA:
5.7		 1gfzA-3ailA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.95A 1qtiA-3ailA:
18.1		 1qtiA-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.14A 1t88B-3ailA:
undetectable		 1t88B-3ailA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		7 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 206
PHE A 197
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
None
DEP  A 304 (-4.1A)
 0.99A 1w6rA-3ailA:
18.6		 1w6rA-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  79
GLY A  80
SER A 150
PHE A 197
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
None
DEP  A 304 (-4.1A)
 0.42A 1w76A-3ailA:
17.6		 1w76A-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  79
GLY A  80
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.93A 1w76A-3ailA:
17.6		 1w76A-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 10 GLY A  78
GLY A  79
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.92A 1w76B-3ailA:
17.7		 1w76B-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PRO A 233
ILE A 105
VAL A 107
TYR A  76
VAL A 131
 None
 1.17A 1z9hD-3ailA:
undetectable		 1z9hD-3ailA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 TYR A 177
GLY A  84
PHE A  30
SER A  88
 None
 1.37A 2a3cA-3ailA:
undetectable		 2a3cA-3ailA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 9 GLY A  78
GLY A  79
SER A 150
ALA A 151
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-1.5A)
DEP  A 304 (-3.5A)
DEP  A 304 (-4.1A)
 0.89A 2aceA-3ailA:
4.8		 2aceA-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		7 / 9 GLY A  79
GLY A  80
SER A 150
ALA A 151
PHE A 206
PHE A 197
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-3.5A)
DEP  A 304 (-4.5A)
None
DEP  A 304 (-4.1A)
 0.86A 2aceA-3ailA:
4.8		 2aceA-3ailA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.04A 2cppA-3ailA:
undetectable		 2cppA-3ailA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 LEU A  92
TYR A  75
ILE A 289
GLY A 147
 None
 0.93A 2du8A-3ailA:
2.1		 2du8A-3ailA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 8 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 0.99A 2eilP-3ailA:
undetectable
2eilW-3ailA:
undetectable		 2eilP-3ailA:
20.54
2eilW-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 8 GLY A  79
GLY A  80
ALA A 151
PHE A 206
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-3.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.98A 2ha4A-3ailA:
18.4		 2ha4A-3ailA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 7 GLY A  79
GLY A  80
ALA A 151
PHE A 206
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-3.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.99A 2ha4B-3ailA:
18.8		 2ha4B-3ailA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.11A 2m56A-3ailA:
undetectable		 2m56A-3ailA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ARG A 221
LEU A 162
ILE A  50
GLY A  52
VAL A 121
 PO4  A 306 (-2.8A)
None
None
None
None
 1.14A 2r5qA-3ailA:
undetectable		 2r5qA-3ailA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ARG A 221
LEU A 162
ILE A  50
GLY A  52
VAL A 121
 PO4  A 306 (-2.8A)
None
None
None
None
 1.14A 2r5qC-3ailA:
undetectable		 2r5qC-3ailA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 8 THR A  37
PRO A  38
ALA A  95
PRO A 280
 None
 1.03A 2v41G-3ailA:
undetectable
2v41H-3ailA:
undetectable		 2v41G-3ailA:
21.88
2v41H-3ailA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.00A 3ablP-3ailA:
undetectable
3ablW-3ailA:
undetectable		 3ablP-3ailA:
20.54
3ablW-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.01A 3ag2C-3ailA:
undetectable		 3ag2C-3ailA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 ASN A 254
ALA A 251
GLY A 249
TYR A 252
 None
 1.12A 3bcrA-3ailA:
5.7		 3bcrA-3ailA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A 175
ALA A 235
SER A 265
VAL A 261
 None
 0.97A 3d2tA-3ailA:
undetectable		 3d2tA-3ailA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ASN A 254
ALA A 251
GLY A 249
TYR A 252
 None
 1.14A 3ddsA-3ailA:
3.5		 3ddsA-3ailA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 4 ILE A 176
GLN A 173
ILE A  96
LEU A 256
 None
 1.35A 3dzyD-3ailA:
undetectable		 3dzyD-3ailA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 10 TYR A  75
ILE A 289
ILE A 292
VAL A 174
GLY A 148
 None
 1.29A 3elzC-3ailA:
undetectable		 3elzC-3ailA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 147
GLY A 148
VAL A 174
LEU A 170
ILE A  96
 None
 1.28A 3h52B-3ailA:
undetectable		 3h52B-3ailA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 GLY A  79
GLY A  80
SER A 150
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.1A)
 0.25A 3o9mA-3ailA:
19.0		 3o9mA-3ailA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 GLY A  79
GLY A  80
SER A 150
HIS A 273
 DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.1A)
 0.34A 3o9mB-3ailA:
19.0		 3o9mB-3ailA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 276
LEU A  92
TYR A  75
LEU A 296
 None
 1.01A 3qeoB-3ailA:
2.4		 3qeoB-3ailA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ALA A 151
GLY A 152
TYR A  76
ALA A 112
PHE A 206
 DEP  A 304 (-3.5A)
None
None
None
DEP  A 304 (-4.5A)
 1.13A 3qxyA-3ailA:
undetectable		 3qxyA-3ailA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ALA A 151
GLY A 152
TYR A  76
ALA A 112
PHE A 206
 DEP  A 304 (-3.5A)
None
None
None
DEP  A 304 (-4.5A)
 1.14A 3qxyB-3ailA:
undetectable
3qxyQ-3ailA:
undetectable		 3qxyB-3ailA:
20.25
3qxyQ-3ailA:
5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		3 / 3 TYR A  62
ASP A  85
ASP A  90
 None
 0.49A 3r24A-3ailA:
2.2		 3r24A-3ailA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ALA A 151
GLY A 152
TYR A  76
ALA A 112
PHE A 206
 DEP  A 304 (-3.5A)
None
None
None
DEP  A 304 (-4.5A)
 1.16A 3rc0A-3ailA:
undetectable		 3rc0A-3ailA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ALA A 151
GLY A 152
TYR A  76
ALA A 112
PHE A 206
 DEP  A 304 (-3.5A)
None
None
None
DEP  A 304 (-4.5A)
 1.14A 3rc0B-3ailA:
undetectable		 3rc0B-3ailA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 HIS A 273
GLY A  80
GLY A  78
TYR A 177
ALA A 112
 DEP  A 304 (-4.1A)
DEP  A 304 (-3.5A)
DEP  A 304 ( 3.8A)
None
None
 1.10A 3vywD-3ailA:
undetectable		 3vywD-3ailA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.10A 3wrhE-3ailA:
undetectable		 3wrhE-3ailA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.08A 3wrjE-3ailA:
undetectable		 3wrjE-3ailA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 8 TYR A 109
TYR A  76
VAL A 131
ILE A  57
 None
 1.11A 4aftD-3ailA:
undetectable
4aftE-3ailA:
undetectable		 4aftD-3ailA:
20.25
4aftE-3ailA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.96A 4ey6A-3ailA:
19.0		 4ey6A-3ailA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A  79
GLY A  80
SER A 150
PHE A 206
HIS A 273
 DEP  A 304 ( 3.8A)
DEP  A 304 (-3.6A)
DEP  A 304 (-3.5A)
DEP  A 304 (-1.5A)
DEP  A 304 (-4.5A)
DEP  A 304 (-4.1A)
 0.96A 4ey6B-3ailA:
18.5		 4ey6B-3ailA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  79
SER A 150
TRP A 205
HIS A 273
GLY A 274
 DEP  A 304 (-3.6A)
DEP  A 304 (-1.5A)
None
DEP  A 304 (-4.1A)
None
 1.43A 4ey7A-3ailA:
18.9		 4ey7A-3ailA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  79
SER A 150
TRP A 205
HIS A 273
GLY A 274
 DEP  A 304 (-3.6A)
DEP  A 304 (-1.5A)
None
DEP  A 304 (-4.1A)
None
 1.46A 4ey7B-3ailA:
18.6		 4ey7B-3ailA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		3 / 3 PRO A  69
TYR A 142
GLY A 140
 None
 0.75A 4g2zA-3ailA:
undetectable		 4g2zA-3ailA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.10A 4g3rA-3ailA:
undetectable		 4g3rA-3ailA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.08A 4g3rB-3ailA:
undetectable		 4g3rB-3ailA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.14A 4l49A-3ailA:
undetectable		 4l49A-3ailA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.11A 4l4cA-3ailA:
undetectable		 4l4cA-3ailA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ALA A 179
SER A 150
GLY A 193
LEU A 198
PRO A 244
 DEP  A 304 ( 4.1A)
DEP  A 304 (-1.5A)
None
DEP  A 304 ( 4.6A)
None
 1.12A 4uilH-3ailA:
undetectable
4uilL-3ailA:
undetectable		 4uilH-3ailA:
21.36
4uilL-3ailA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ALA A 179
SER A 150
GLY A 207
LEU A 198
PRO A 244
 DEP  A 304 ( 4.1A)
DEP  A 304 (-1.5A)
None
DEP  A 304 ( 4.6A)
None
 1.06A 4uilH-3ailA:
undetectable
4uilL-3ailA:
undetectable		 4uilH-3ailA:
21.36
4uilL-3ailA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A  45
ARG A  94
ARG A  39
GLU A  87
 None
 1.32A 4zzcA-3ailA:
undetectable
4zzcB-3ailA:
undetectable		 4zzcA-3ailA:
22.63
4zzcB-3ailA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A  45
ARG A  94
ARG A  39
GLU A  87
 None
 1.26A 4zzcB-3ailA:
undetectable
4zzcC-3ailA:
undetectable		 4zzcB-3ailA:
22.63
4zzcC-3ailA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 LEU A 175
ALA A 235
SER A 265
VAL A 261
 None
 0.83A 5a6iA-3ailA:
undetectable		 5a6iA-3ailA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.02A 5b1bC-3ailA:
undetectable
5b1bJ-3ailA:
undetectable		 5b1bC-3ailA:
20.54
5b1bJ-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.00A 5b1bP-3ailA:
undetectable
5b1bW-3ailA:
undetectable		 5b1bP-3ailA:
20.54
5b1bW-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ARG A 221
LEU A 162
ILE A  50
GLY A  52
VAL A 121
 PO4  A 306 (-2.8A)
None
None
None
None
 0.96A 5kr2D-3ailA:
undetectable		 5kr2D-3ailA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 ALA A 145
VAL A 174
PHE A 300
ILE A  96
 None
 1.01A 5of1A-3ailA:
undetectable		 5of1A-3ailA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 ALA A 145
VAL A 174
PHE A 300
ILE A 292
 None
 0.91A 5of1A-3ailA:
undetectable		 5of1A-3ailA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 5 ALA A 145
VAL A 174
PHE A 300
ILE A 292
 None
 0.90A 5of1B-3ailA:
undetectable		 5of1B-3ailA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A 147
GLY A 152
VAL A 131
PHE A 138
ILE A 105
 DEP  A 304 ( 3.8A)
None
None
None
None
None
 1.24A 5vimA-3ailA:
undetectable		 5vimA-3ailA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  78
GLY A 147
GLY A 152
VAL A 131
PHE A 138
ILE A 105
 DEP  A 304 ( 3.8A)
None
None
None
None
None
 1.25A 5vimB-3ailA:
undetectable		 5vimB-3ailA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 8 ILE A 176
TYR A 172
VAL A 266
ASP A 243
 None
 1.03A 5vlmF-3ailA:
undetectable		 5vlmF-3ailA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A 117
TYR A 210
LEU A 155
VAL A 158
 None
 1.01A 5wk9A-3ailA:
undetectable		 5wk9A-3ailA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		3 / 3 TYR A 301
ARG A 297
THR A  66
 None
 0.98A 5z84J-3ailA:
undetectable		 5z84J-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.05A 5z84P-3ailA:
undetectable
5z84W-3ailA:
undetectable		 5z84P-3ailA:
20.54
5z84W-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.05A 5z85P-3ailA:
undetectable
5z85W-3ailA:
undetectable		 5z85P-3ailA:
20.54
5z85W-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.05A 5z86P-3ailA:
undetectable
5z86W-3ailA:
undetectable		 5z86P-3ailA:
20.54
5z86W-3ailA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A 200
GLN A 208
PHE A 182
LEU A 184
 None
None
MRD  A 305 (-4.4A)
None
 1.06A 5zcoP-3ailA:
undetectable
5zcoW-3ailA:
undetectable		 5zcoP-3ailA:
20.54
5zcoW-3ailA:
11.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IEY_A_CLMA401_0
(ESTERASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ASP A 149
LEU A 198
HIS A 273
GLY A 274
SER A 277
 None
DEP  A 304 ( 4.6A)
DEP  A 304 (-4.1A)
None
None
 0.35A 6ieyA-3ailA:
41.9
6ieyB-3ailA:
41.9		 6ieyA-3ailA:
36.47
6ieyB-3ailA:
36.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 3ail 303AA LONG
HYPOTHETICAL
ESTERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 105
LEU A 296
GLY A 140
PHE A 138
ILE A 144
 None
 1.10A 6qxsB-3ailA:
undetectable		 6qxsB-3ailA:
22.34