SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ajb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 MET A 295
LEU A 291
LEU A 209
LEU A 191
VAL A 190
 None
 1.19A 1hrkA-3ajbA:
undetectable		 1hrkA-3ajbA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		4 / 8 SER A 199
LEU A 200
ILE A 328
ILE A 325
 None
 0.90A 1sbrA-3ajbA:
undetectable		 1sbrA-3ajbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A 205
ILE A 325
ILE A 326
SER A  86
LEU A 209
 None
 0.98A 1xdkF-3ajbA:
1.7		 1xdkF-3ajbA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 11 MET A 295
LEU A 291
LEU A 209
LEU A 191
VAL A 190
 None
 1.20A 2po5B-3ajbA:
undetectable		 2po5B-3ajbA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 MET A 238
LEU A 234
LEU A 280
ILE A 183
VAL A 354
 None
 1.24A 2po7B-3ajbA:
undetectable		 2po7B-3ajbA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A 264
ASN A 265
LEU A 263
VAL A 131
LEU A 271
 None
 1.06A 2q7kA-3ajbA:
undetectable		 2q7kA-3ajbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A 264
ASN A 265
VAL A 131
MET A 239
LEU A 271
 None
 1.15A 2q7kA-3ajbA:
undetectable		 2q7kA-3ajbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 19
PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		4 / 7 LEU B  18
LEU B  21
LEU A 101
GLU A 105
 None
 0.88A 2vq5B-3ajbB:
undetectable		 2vq5B-3ajbB:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 VAL A 117
SER A 121
LEU A  80
 None
 0.64A 3n8xA-3ajbA:
undetectable		 3n8xA-3ajbA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 19
PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		4 / 7 PRO A 327
LEU B  18
ALA B  25
PHE B  29
 None
 0.96A 3tehB-3ajbA:
undetectable		 3tehB-3ajbA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		4 / 6 ARG A  54
GLY A 138
ALA A 145
GLN A  62
 None
 1.07A 4g0uA-3ajbA:
undetectable		 4g0uA-3ajbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.98A 4k8cA-3ajbA:
undetectable		 4k8cA-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.97A 4kahA-3ajbA:
undetectable		 4kahA-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.96A 4kahB-3ajbA:
undetectable		 4kahB-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.97A 4kanA-3ajbA:
undetectable		 4kanA-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.98A 4kanB-3ajbA:
undetectable		 4kanB-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.96A 4kbeB-3ajbA:
undetectable		 4kbeB-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 SER A 167
TYR A 164
PRO A 240
 None
 0.97A 4lbgB-3ajbA:
undetectable		 4lbgB-3ajbA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 19
PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 9 LEU B  26
LEU A 107
ILE A 103
SER A  88
ALA A  91
 None
 1.38A 4z69A-3ajbB:
undetectable		 4z69A-3ajbB:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A 179
GLY A 173
GLY A 175
ILE A 168
LEU A  76
 None
 0.98A 6ectA-3ajbA:
undetectable		 6ectA-3ajbA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A 179
GLY A 173
GLY A 175
ILE A 168
LEU A  76
 None
 0.99A 6ecxA-3ajbA:
undetectable		 6ecxA-3ajbA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		3 / 3 HIS A 334
ARG A 114
ILE A 333
 None
 0.84A 6fgdA-3ajbA:
undetectable		 6fgdA-3ajbA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A  84
ILE A 110
LEU A  93
ILE A 326
ALA A 323
 None
 1.35A 6qxsD-3ajbA:
undetectable		 6qxsD-3ajbA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 3ajb PEROXISOMAL
BIOGENESIS FACTOR 3
(Homo
sapiens) 		5 / 12 LEU A  84
ILE A 110
LEU A  93
ILE A 326
ALA A 323
 None
 1.33A 6qyaB-3ajbA:
undetectable		 6qyaB-3ajbA:
21.43