SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ajf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 5 LEU A  23
ILE A  37
LEU A  40
SER A  41
 None
 0.91A 2byoA-3ajfA:
undetectable		 2byoA-3ajfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		3 / 3 LEU A  97
PRO A  96
LEU A 100
 None
 0.62A 2po5B-3ajfA:
undetectable		 2po5B-3ajfA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		3 / 3 LEU A  97
PRO A  96
LEU A 100
 None
 0.56A 2po7B-3ajfA:
undetectable		 2po7B-3ajfA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		3 / 3 LEU A  97
PRO A  96
LEU A 100
 None
 0.55A 3hcrA-3ajfA:
undetectable		 3hcrA-3ajfA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 8 LEU A  42
SER A  41
LEU A  83
ILE A  46
 None
 0.86A 3ln1A-3ajfA:
undetectable		 3ln1A-3ajfA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 7 LEU A  42
SER A  41
LEU A  83
ILE A  46
 None
 0.88A 3ln1B-3ajfA:
undetectable		 3ln1B-3ajfA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.06A 5z84P-3ajfA:
undetectable
5z84W-3ajfA:
undetectable		 5z84P-3ajfA:
19.07
5z84W-3ajfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.00A 5z86C-3ajfA:
undetectable
5z86J-3ajfA:
undetectable		 5z86C-3ajfA:
19.07
5z86J-3ajfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.00A 5z86P-3ajfA:
undetectable
5z86W-3ajfA:
undetectable		 5z86P-3ajfA:
19.07
5z86W-3ajfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.05A 5zcoP-3ajfA:
undetectable
5zcoW-3ajfA:
undetectable		 5zcoP-3ajfA:
19.07
5zcoW-3ajfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.04A 5zcpC-3ajfA:
undetectable
5zcpJ-3ajfA:
undetectable		 5zcpC-3ajfA:
19.07
5zcpJ-3ajfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ajf NON-STRUCTURAL
PROTEIN 3
(Rice
hoja
blanca
tenuivirus) 		4 / 6 GLN A  61
PHE A  54
LEU A  47
PHE A  43
 None
 1.08A 5zcpP-3ajfA:
undetectable
5zcpW-3ajfA:
undetectable		 5zcpP-3ajfA:
19.07
5zcpW-3ajfA:
22.00