SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ajx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.19A 1dreA-3ajxA:
undetectable		 1dreA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.21A 1dreA-3ajxA:
undetectable		 1dreA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.13A 1dyiA-3ajxA:
undetectable		 1dyiA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.07A 1dyiB-3ajxA:
undetectable		 1dyiB-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		3 / 4 LYS A1116
ALA A1120
MET A1133
 None
 1.05A 1hk3A-3ajxA:
undetectable		 1hk3A-3ajxA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.17A 1jolA-3ajxA:
undetectable		 1jolA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.11A 1jolB-3ajxA:
undetectable		 1jolB-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 11 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.15A 1jomA-3ajxA:
undetectable		 1jomA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 11 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.16A 1jomA-3ajxA:
undetectable		 1jomA-3ajxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.30A 1k2rA-3ajxA:
undetectable
1k2rB-3ajxA:
undetectable		 1k2rA-3ajxA:
20.38
1k2rB-3ajxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.31A 1lzxA-3ajxA:
undetectable
1lzxB-3ajxA:
undetectable		 1lzxA-3ajxA:
20.38
1lzxB-3ajxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 1m00A-3ajxA:
undetectable
1m00B-3ajxA:
undetectable		 1m00A-3ajxA:
20.38
1m00B-3ajxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.22A 1mmvA-3ajxA:
undetectable
1mmvB-3ajxA:
undetectable		 1mmvA-3ajxA:
20.38
1mmvB-3ajxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.25A 1mmvA-3ajxA:
undetectable
1mmvB-3ajxA:
undetectable		 1mmvA-3ajxA:
20.38
1mmvB-3ajxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.26A 1om4A-3ajxA:
undetectable
1om4B-3ajxA:
undetectable		 1om4A-3ajxA:
20.24
1om4B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 1p6hA-3ajxA:
undetectable
1p6hB-3ajxA:
undetectable		 1p6hA-3ajxA:
20.28
1p6hB-3ajxA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.50A 1p6kA-3ajxA:
undetectable
1p6kB-3ajxA:
undetectable		 1p6kA-3ajxA:
20.28
1p6kB-3ajxA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 8 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 1rs6A-3ajxA:
undetectable
1rs6B-3ajxA:
undetectable		 1rs6A-3ajxA:
20.28
1rs6B-3ajxA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.11A 1tdrA-3ajxA:
undetectable		 1tdrA-3ajxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 5 ALA A1188
TYR A1190
ILE A1189
ASP A1008
 None
 1.21A 1upfA-3ajxA:
undetectable		 1upfA-3ajxA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 5 ALA A1188
TYR A1190
ILE A1189
ASP A1008
 None
 1.17A 1upfC-3ajxA:
undetectable		 1upfC-3ajxA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.24A 1zzqA-3ajxA:
undetectable
1zzqB-3ajxA:
undetectable		 1zzqA-3ajxA:
20.33
1zzqB-3ajxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 8 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.24A 2g6hA-3ajxA:
undetectable
2g6hB-3ajxA:
undetectable		 2g6hA-3ajxA:
20.33
2g6hB-3ajxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.23A 2g6kA-3ajxA:
undetectable
2g6kB-3ajxA:
undetectable		 2g6kA-3ajxA:
20.33
2g6kB-3ajxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.25A 2g6mA-3ajxA:
undetectable
2g6mB-3ajxA:
undetectable		 2g6mA-3ajxA:
20.33
2g6mB-3ajxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 2g6mA-3ajxA:
undetectable
2g6mB-3ajxA:
undetectable		 2g6mA-3ajxA:
20.33
2g6mB-3ajxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.26A 3b3mA-3ajxA:
0.3
3b3mB-3ajxA:
undetectable		 3b3mA-3ajxA:
20.24
3b3mB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.29A 3b3nA-3ajxA:
0.7
3b3nB-3ajxA:
0.7		 3b3nA-3ajxA:
20.24
3b3nB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.26A 3b3oA-3ajxA:
undetectable
3b3oB-3ajxA:
undetectable		 3b3oA-3ajxA:
20.24
3b3oB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.30A 3b3pA-3ajxA:
undetectable
3b3pB-3ajxA:
undetectable		 3b3pA-3ajxA:
20.24
3b3pB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.28A 3hsnA-3ajxA:
undetectable
3hsnB-3ajxA:
undetectable		 3hsnA-3ajxA:
20.24
3hsnB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 3hsnA-3ajxA:
undetectable
3hsnB-3ajxA:
undetectable		 3hsnA-3ajxA:
20.24
3hsnB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.30A 3hsoA-3ajxA:
undetectable
3hsoB-3ajxA:
undetectable		 3hsoA-3ajxA:
20.24
3hsoB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 3hsoA-3ajxA:
undetectable
3hsoB-3ajxA:
undetectable		 3hsoA-3ajxA:
20.24
3hsoB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.17A 3ia4D-3ajxA:
undetectable		 3ia4D-3ajxA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 3jt9A-3ajxA:
undetectable
3jt9B-3ajxA:
undetectable		 3jt9A-3ajxA:
20.24
3jt9B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 3jwtA-3ajxA:
0.6
3jwtB-3ajxA:
undetectable		 3jwtA-3ajxA:
20.24
3jwtB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.26A 3jwvA-3ajxA:
undetectable
3jwvB-3ajxA:
undetectable		 3jwvA-3ajxA:
20.24
3jwvB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 11 ALA A1185
ILE A1189
GLY A1187
LEU A1202
ALA A1198
 None
None
SO4  A6001 (-3.9A)
None
None
 1.19A 3kw2A-3ajxA:
4.3		 3kw2A-3ajxA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 6 SER A1162
GLN A1004
PHE A1130
PHE A1057
 None
 1.28A 3lskB-3ajxA:
undetectable		 3lskB-3ajxA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 6 SER A1162
GLN A1004
PHE A1130
PHE A1057
 None
 1.31A 3lskD-3ajxA:
undetectable		 3lskD-3ajxA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 3n5vA-3ajxA:
undetectable
3n5vB-3ajxA:
undetectable		 3n5vA-3ajxA:
20.24
3n5vB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.30A 3nlmA-3ajxA:
undetectable
3nlmB-3ajxA:
0.7		 3nlmA-3ajxA:
20.24
3nlmB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 8 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 3nlyA-3ajxA:
undetectable
3nlyB-3ajxA:
0.4		 3nlyA-3ajxA:
20.24
3nlyB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.28A 3nnzA-3ajxA:
undetectable
3nnzB-3ajxA:
undetectable		 3nnzA-3ajxA:
20.24
3nnzB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.30A 3pneA-3ajxA:
undetectable
3pneB-3ajxA:
undetectable		 3pneA-3ajxA:
20.24
3pneB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 3pnfA-3ajxA:
undetectable
3pnfB-3ajxA:
undetectable		 3pnfA-3ajxA:
20.24
3pnfB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 3pnfA-3ajxA:
undetectable
3pnfB-3ajxA:
undetectable		 3pnfA-3ajxA:
20.24
3pnfB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.31A 3q9aA-3ajxA:
undetectable
3q9aB-3ajxA:
undetectable		 3q9aA-3ajxA:
20.24
3q9aB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.16A 3ql0A-3ajxA:
undetectable		 3ql0A-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.15A 3ql0A-3ajxA:
undetectable		 3ql0A-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.30A 3rqjA-3ajxA:
undetectable
3rqjB-3ajxA:
undetectable		 3rqjA-3ajxA:
20.24
3rqjB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 3rqkA-3ajxA:
undetectable
3rqkB-3ajxA:
0.7		 3rqkA-3ajxA:
20.24
3rqkB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 11 ALA A1199
ILE A1007
GLY A1186
ALA A1185
VAL A1182
 None
None
SO4  A6001 (-3.2A)
None
None
 1.17A 3rukD-3ajxA:
undetectable		 3rukD-3ajxA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 3svpA-3ajxA:
undetectable
3svpB-3ajxA:
undetectable		 3svpA-3ajxA:
20.24
3svpB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 3ufpA-3ajxA:
undetectable
3ufpB-3ajxA:
undetectable		 3ufpA-3ajxA:
20.24
3ufpB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.33A 3ufrA-3ajxA:
undetectable
3ufrB-3ajxA:
undetectable		 3ufrA-3ajxA:
20.24
3ufrB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.34A 3ufsA-3ajxA:
undetectable
3ufsB-3ajxA:
undetectable		 3ufsA-3ajxA:
20.24
3ufsB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.28A 3ufuA-3ajxA:
undetectable
3ufuB-3ajxA:
undetectable		 3ufuA-3ajxA:
20.24
3ufuB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.42A 4c39A-3ajxA:
undetectable
4c39B-3ajxA:
undetectable		 4c39A-3ajxA:
20.24
4c39B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 GLY A1127
ASP A1089
ILE A1092
ALA A1095
ARG A1119
 None
 1.03A 4dx5B-3ajxA:
undetectable		 4dx5B-3ajxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 GLY A1127
ASP A1089
ILE A1092
VAL A1083
ARG A1119
 None
 1.17A 4dx5B-3ajxA:
undetectable		 4dx5B-3ajxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.08A 4ej1B-3ajxA:
undetectable		 4ej1B-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 6 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.28A 4imuA-3ajxA:
undetectable
4imuB-3ajxA:
undetectable		 4imuA-3ajxA:
20.24
4imuB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.37A 4jsfA-3ajxA:
undetectable
4jsfB-3ajxA:
undetectable		 4jsfA-3ajxA:
20.24
4jsfB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.27A 4jsjA-3ajxA:
undetectable
4jsjB-3ajxA:
undetectable		 4jsjA-3ajxA:
20.24
4jsjB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.28A 4k5dA-3ajxA:
undetectable
4k5dB-3ajxA:
undetectable		 4k5dA-3ajxA:
20.24
4k5dB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.36A 4k5dA-3ajxA:
undetectable
4k5dB-3ajxA:
undetectable		 4k5dA-3ajxA:
20.24
4k5dB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.29A 4k5eA-3ajxA:
undetectable
4k5eB-3ajxA:
undetectable		 4k5eA-3ajxA:
20.24
4k5eB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.12A 4nx6A-3ajxA:
undetectable		 4nx6A-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.04A 4pstA-3ajxA:
undetectable		 4pstA-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 11 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.07A 4qlfA-3ajxA:
undetectable		 4qlfA-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.15A 4qlgA-3ajxA:
undetectable		 4qlgA-3ajxA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1055
LEU A1080
 None
 1.16A 4qlgA-3ajxA:
undetectable		 4qlgA-3ajxA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 ALA A1180
PHE A1130
LYS A1129
ILE A1028
LEU A1080
 None
 1.13A 4rgcA-3ajxA:
undetectable		 4rgcA-3ajxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		5 / 12 GLY A1127
ASP A1089
ILE A1092
ALA A1095
ARG A1119
 None
 1.06A 4u8vB-3ajxA:
undetectable		 4u8vB-3ajxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.23A 4uh1A-3ajxA:
undetectable
4uh1B-3ajxA:
undetectable		 4uh1A-3ajxA:
20.24
4uh1B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.37A 4uh2A-3ajxA:
undetectable
4uh2B-3ajxA:
undetectable		 4uh2A-3ajxA:
20.24
4uh2B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.37A 4uh3A-3ajxA:
undetectable
4uh3B-3ajxA:
undetectable		 4uh3A-3ajxA:
20.24
4uh3B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.25A 4uppA-3ajxA:
undetectable
4uppB-3ajxA:
undetectable		 4uppA-3ajxA:
20.24
4uppB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.28A 4v3uA-3ajxA:
undetectable
4v3uB-3ajxA:
undetectable		 4v3uA-3ajxA:
19.15
4v3uB-3ajxA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.29A 4v3yA-3ajxA:
undetectable
4v3yB-3ajxA:
undetectable		 4v3yA-3ajxA:
20.24
4v3yB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 9 SER A1162
ALA A1180
LEU A1150
LEU A1147
 None
 0.92A 4xtaA-3ajxA:
undetectable		 4xtaA-3ajxA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 5 ALA A1185
HIS A1134
ALA A1164
GLU A1030
 None
MG  A9100 ( 4.5A)
None
MG  A9100 (-2.9A)
 1.41A 5a06C-3ajxA:
3.5
5a06D-3ajxA:
2.6		 5a06C-3ajxA:
22.19
5a06D-3ajxA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.39A 5ad4A-3ajxA:
undetectable
5ad4B-3ajxA:
undetectable		 5ad4A-3ajxA:
20.24
5ad4B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.32A 5ad5A-3ajxA:
undetectable
5ad5B-3ajxA:
undetectable		 5ad5A-3ajxA:
20.24
5ad5B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 5ad6A-3ajxA:
undetectable
5ad6B-3ajxA:
undetectable		 5ad6A-3ajxA:
20.24
5ad6B-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.26A 5aglA-3ajxA:
undetectable
5aglB-3ajxA:
undetectable		 5aglA-3ajxA:
20.24
5aglB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.36A 5agpA-3ajxA:
undetectable
5agpB-3ajxA:
undetectable		 5agpA-3ajxA:
20.24
5agpB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.45A 5fvqA-3ajxA:
undetectable
5fvqB-3ajxA:
0.8		 5fvqA-3ajxA:
20.24
5fvqB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.42A 5fvsA-3ajxA:
undetectable
5fvsB-3ajxA:
undetectable		 5fvsA-3ajxA:
20.24
5fvsB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.43A 5fvuA-3ajxA:
0.7
5fvuB-3ajxA:
undetectable		 5fvuA-3ajxA:
19.10
5fvuB-3ajxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.33A 5fvwA-3ajxA:
undetectable
5fvwB-3ajxA:
undetectable		 5fvwA-3ajxA:
19.10
5fvwB-3ajxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.36A 5fvxA-3ajxA:
undetectable
5fvxB-3ajxA:
undetectable		 5fvxA-3ajxA:
19.10
5fvxB-3ajxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 5 ALA A1078
ALA A1058
ILE A1044
LEU A1041
 None
 0.58A 5jncD-3ajxA:
undetectable		 5jncD-3ajxA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.36A 5vuiA-3ajxA:
undetectable
5vuiB-3ajxA:
undetectable		 5vuiA-3ajxA:
20.24
5vuiB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.27A 5vujA-3ajxA:
undetectable
5vujB-3ajxA:
0.7		 5vujA-3ajxA:
20.24
5vujB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.36A 5vurA-3ajxA:
undetectable
5vurB-3ajxA:
undetectable		 5vurA-3ajxA:
20.24
5vurB-3ajxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.30A 6auuA-3ajxA:
0.7
6auuB-3ajxA:
undetectable		 6auuA-3ajxA:
14.49
6auuB-3ajxA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 PHE A1074
GLU A1069
MET A1060
VAL A1106
 None
 1.40A 6av0A-3ajxA:
undetectable
6av0B-3ajxA:
undetectable		 6av0A-3ajxA:
14.49
6av0B-3ajxA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE
(Mycobacterium
gastri) 		4 / 7 MET A1060
VAL A1106
PHE A1074
GLU A1069
 None
 1.36A 6cicA-3ajxA:
undetectable
6cicB-3ajxA:
0.6		 6cicA-3ajxA:
14.49
6cicB-3ajxA:
14.49