SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		4 / 5 LEU A  89
LEU A  60
ILE A  99
ALA A  65
 None
 0.73A 2i2zA-3akaA:
2.2		 2i2zA-3akaA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		5 / 12 ASP A  94
VAL A 168
ILE A  10
ILE A  67
ALA A  97
 None
 1.22A 3ohtA-3akaA:
undetectable
3ohtB-3akaA:
undetectable		 3ohtA-3akaA:
18.65
3ohtB-3akaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		5 / 11 PHE A 103
PHE A 131
LEU A  37
THR A 124
ALA A 125
 None
 1.42A 4dx7A-3akaA:
0.0		 4dx7A-3akaA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		4 / 7 TRP A  61
ASP A  29
PHE A  30
SER A  31
 None
CA  A 171 (-2.2A)
None
None
 1.36A 4o4dA-3akaA:
undetectable		 4o4dA-3akaA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		5 / 12 LEU A  60
SER A  28
ALA A  36
ALA A  33
GLY A  32
 None
 1.15A 5tzoB-3akaA:
undetectable		 5tzoB-3akaA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLY A 109
ARG A 126
VAL A 119
ASP A 123
 None
 1.02A 5vlmA-3akaA:
undetectable		 5vlmA-3akaA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		5 / 12 ALA A  33
GLY A  32
SER A  31
LEU A  53
PHE A 131
 None
 1.08A 5w7pA-3akaA:
undetectable		 5w7pA-3akaA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		4 / 4 ASP A  29
SER A  28
ASP A  26
HIS A  24
 CA  A 171 (-2.2A)
None
None
None
 1.47A 5wyqB-3akaA:
undetectable		 5wyqB-3akaA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3aka PUTATIVE CALCIUM
BINDING PROTEIN
(Streptomyces
coelicolor) 		5 / 12 GLY A  42
TYR A  54
ARG A  49
LEU A  53
GLY A  50
 None
 1.32A 6bp4B-3akaA:
undetectable		 6bp4B-3akaA:
19.53