SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3akf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 5 HIS A 336
SER A 368
LEU A 361
GLY A 376
 GOL  A 596 (-3.5A)
None
None
None
 1.02A 1a4lB-3akfA:
undetectable		 1a4lB-3akfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 ALA A  93
VAL A  99
TRP A 100
 None
 0.45A 1c4dA-3akfA:
undetectable
1c4dB-3akfA:
undetectable		 1c4dA-3akfA:
2.42
1c4dB-3akfA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 TRP A 100
ALA A  93
VAL A  99
 None
 0.54A 1c4dA-3akfA:
undetectable
1c4dB-3akfA:
undetectable		 1c4dA-3akfA:
2.42
1c4dB-3akfA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 ALA A  93
VAL A  99
TRP A 100
 None
 0.70A 1c4dC-3akfA:
undetectable
1c4dD-3akfA:
undetectable		 1c4dC-3akfA:
2.42
1c4dD-3akfA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 TRP A 100
ALA A  93
VAL A  99
 None
 0.79A 1c4dC-3akfA:
undetectable
1c4dD-3akfA:
undetectable		 1c4dC-3akfA:
2.42
1c4dD-3akfA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 SER A 161
VAL A 194
ALA A 150
PHE A 132
 None
 1.00A 1dmiA-3akfA:
undetectable
1dmiB-3akfA:
undetectable		 1dmiA-3akfA:
21.44
1dmiB-3akfA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 GLU A 267
TYR A  31
LEU A  51
LYS A 270
 None
 1.19A 1rmtB-3akfA:
undetectable		 1rmtB-3akfA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 ARG A 332
ASN A 433
ASN A 328
ASP A 448
 None
 1.26A 1rs6A-3akfA:
undetectable		 1rs6A-3akfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.43A 1vidA-3akfA:
undetectable		 1vidA-3akfA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 SER A 368
ALA A 362
LEU A 361
PHE A 397
VAL A 386
 None
 1.30A 1vpoH-3akfA:
undetectable
1vpoL-3akfA:
undetectable		 1vpoH-3akfA:
17.17
1vpoL-3akfA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.38A 2cl5B-3akfA:
undetectable		 2cl5B-3akfA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.77A 2v2gA-3akfA:
undetectable
2v2gB-3akfA:
undetectable		 2v2gA-3akfA:
20.97
2v2gB-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.74A 2v2gA-3akfA:
undetectable
2v2gB-3akfA:
undetectable		 2v2gA-3akfA:
20.97
2v2gB-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.78A 2v2gC-3akfA:
undetectable
2v2gD-3akfA:
undetectable		 2v2gC-3akfA:
20.97
2v2gD-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.75A 2v2gC-3akfA:
undetectable
2v2gD-3akfA:
undetectable		 2v2gC-3akfA:
20.97
2v2gD-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.72A 2v32A-3akfA:
undetectable
2v32B-3akfA:
undetectable		 2v32A-3akfA:
20.97
2v32B-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.76A 2v32A-3akfA:
undetectable
2v32B-3akfA:
undetectable		 2v32A-3akfA:
20.97
2v32B-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PRO A 375
THR A 253
VAL A 315
ALA A 351
 None
 1.01A 2v32A-3akfA:
undetectable
2v32B-3akfA:
undetectable		 2v32A-3akfA:
20.97
2v32B-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.81A 2v32C-3akfA:
undetectable
2v32D-3akfA:
undetectable		 2v32C-3akfA:
20.97
2v32D-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.79A 2v32C-3akfA:
undetectable
2v32D-3akfA:
undetectable		 2v32C-3akfA:
20.97
2v32D-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.81A 2v41C-3akfA:
undetectable
2v41D-3akfA:
undetectable		 2v41C-3akfA:
20.97
2v41D-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.79A 2v41C-3akfA:
undetectable
2v41D-3akfA:
undetectable		 2v41C-3akfA:
20.97
2v41D-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 THR A 127
PRO A 128
VAL A 129
PRO A 177
 None
 0.66A 2v41E-3akfA:
undetectable
2v41F-3akfA:
undetectable		 2v41E-3akfA:
20.97
2v41F-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.74A 2v41E-3akfA:
undetectable
2v41F-3akfA:
undetectable		 2v41E-3akfA:
20.97
2v41F-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PRO A 177
THR A 127
PRO A 128
VAL A 129
 None
 0.76A 2v41G-3akfA:
undetectable
2v41H-3akfA:
undetectable		 2v41G-3akfA:
20.97
2v41H-3akfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ALA A 213
SER A 243
PRO A 245
THR A 240
LEU A 222
 None
 1.03A 2zifA-3akfA:
undetectable		 2zifA-3akfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.36A 2zvjA-3akfA:
undetectable		 2zvjA-3akfA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 8 PHE A  33
ILE A  23
ALA A  55
VAL A 275
 None
 0.78A 3me6B-3akfA:
undetectable		 3me6B-3akfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 TYR A 384
LEU A 444
ARG A 436
 None
 0.79A 3sufB-3akfA:
undetectable		 3sufB-3akfA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 10 PHE A 397
SER A 394
ALA A 362
LEU A 361
ALA A 453
 None
 1.31A 4fe1A-3akfA:
undetectable
4fe1J-3akfA:
undetectable		 4fe1A-3akfA:
22.31
4fe1J-3akfA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 ASP A 135
ASN A 195
SER A 262
 GOL  A 591 (-3.0A)
None
None
 0.74A 4obwA-3akfA:
undetectable		 4obwA-3akfA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 SER A 212
LEU A 274
PHE A 263
PHE A 247
GLY A 259
 None
 1.28A 4pevC-3akfA:
undetectable		 4pevC-3akfA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.41A 4xucA-3akfA:
undetectable		 4xucA-3akfA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.43A 5fhrA-3akfA:
undetectable		 5fhrA-3akfA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ASN A 422
GLU A 419
GLY A 425
TYR A 423
TYR A 421
 None
 1.42A 5fhrB-3akfA:
undetectable		 5fhrB-3akfA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 VAL A  37
ALA A  35
VAL A  44
ARG A  42
 None
 0.89A 5fpdA-3akfA:
undetectable		 5fpdA-3akfA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 7 VAL A  37
ALA A  35
VAL A  44
ARG A  42
 None
 0.90A 5fpdB-3akfA:
undetectable		 5fpdB-3akfA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 12 ILE A  83
TYR A  90
VAL A  89
ALA A  77
GLY A 197
 None
None
None
GOL  A 591 ( 4.4A)
NA  A 502 ( 4.7A)
 0.99A 5igjA-3akfA:
undetectable		 5igjA-3akfA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 5 GLY A  72
THR A  96
GLY A 259
LEU A 134
 None
 0.91A 5jlcA-3akfA:
undetectable		 5jlcA-3akfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 9 ALA A 150
ASP A 135
ILE A 164
THR A 127
PRO A 128
 None
GOL  A 591 (-3.0A)
None
None
None
 1.23A 5kr2A-3akfA:
undetectable		 5kr2A-3akfA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 9 ALA A 150
ASP A 135
ILE A 164
THR A 127
PRO A 128
 None
GOL  A 591 (-3.0A)
None
None
None
 1.26A 5kr2C-3akfA:
undetectable		 5kr2C-3akfA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 10 ALA A 229
LYS A 166
ILE A 164
ILE A 180
GLN A 202
 None
 1.11A 5nukA-3akfA:
undetectable		 5nukA-3akfA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		5 / 10 ALA A 229
VAL A 141
LYS A 166
ILE A 164
ILE A 180
 None
 1.08A 5nukA-3akfA:
undetectable		 5nukA-3akfA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		3 / 3 ARG A 279
PRO A 288
TYR A 220
 None
 0.88A 5tzoB-3akfA:
undetectable		 5tzoB-3akfA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II
(Streptomyces
avermitilis) 		4 / 5 LEU A 435
THR A 450
ARG A 426
PRO A 439
 None
 1.41A 6ew0H-3akfA:
undetectable		 6ew0H-3akfA:
12.71