SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3al5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		3 / 3 ASN A 166
TYR A 264
SER A 145
 None
 0.91A 2gvcB-3al5A:
undetectable		 2gvcB-3al5A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		3 / 3 ASN A 166
TYR A 264
SER A 145
 None
 0.90A 2gvcE-3al5A:
undetectable		 2gvcE-3al5A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		5 / 10 HIS A 160
ASP A 162
LYS A 175
ILE A 229
HIS A 235
 None
 0.52A 3kcxA-3al5A:
22.4		 3kcxA-3al5A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		5 / 10 TYR A 106
HIS A 160
ASP A 162
ILE A 229
HIS A 235
 None
 0.97A 3kcxA-3al5A:
22.4		 3kcxA-3al5A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		3 / 3 SER A 151
SER A 152
HIS A  61
 None
 0.84A 3mzeA-3al5A:
undetectable		 3mzeA-3al5A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3al5 JMJC
DOMAIN-CONTAINING
PROTEIN C2ORF60
(Homo
sapiens) 		3 / 3 LEU A 107
ARG A 149
MET A 164
 None
 0.88A 4m11C-3al5A:
undetectable		 4m11C-3al5A:
19.01