SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		3 / 3 ASN A  49
PHE A   6
VAL A  80
 None
 0.78A 1kijA-3alyA:
undetectable		 1kijA-3alyA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A 109
LEU A  59
LEU A  66
GLY A  67
 None
 0.87A 1n13D-3alyA:
1.1
1n13E-3alyA:
undetectable		 1n13D-3alyA:
24.84
1n13E-3alyA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 8 SER A 128
ASP A   7
ASP A 125
GLU A  52
 None
 1.08A 2j2pA-3alyA:
undetectable
2j2pB-3alyA:
undetectable		 2j2pA-3alyA:
19.27
2j2pB-3alyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 6 SER A 128
ASP A   7
ASP A 125
GLU A  52
 None
 1.20A 2j2pE-3alyA:
undetectable
2j2pF-3alyA:
undetectable		 2j2pE-3alyA:
19.27
2j2pF-3alyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A  57
PRO A  71
LEU A 113
ILE A  73
 None
 0.83A 2q83A-3alyA:
undetectable		 2q83A-3alyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A  57
PRO A  71
LEU A 113
ILE A  73
 None
 0.99A 2q83B-3alyA:
undetectable		 2q83B-3alyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		3 / 3 LEU A  66
ARG A  65
ILE A  68
 None
 0.64A 2xn5B-3alyA:
undetectable		 2xn5B-3alyA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 9 THR A  62
LEU A 113
SER A  77
ILE A  25
GLY A  34
 None
 1.14A 3cv9A-3alyA:
undetectable		 3cv9A-3alyA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A 120
GLU A 119
TRP A 115
 None
 1.19A 3hrdA-3alyA:
undetectable
3hrdE-3alyA:
undetectable
3hrdF-3alyA:
undetectable		 3hrdA-3alyA:
18.16
3hrdE-3alyA:
18.16
3hrdF-3alyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  66
GLY A  67
ALA A 102
PHE A  23
LEU A  56
 None
 1.05A 3vywC-3alyA:
undetectable		 3vywC-3alyA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A   3
MET A  63
THR A  62
LEU A  59
 None
 1.04A 3wg7N-3alyA:
undetectable
3wg7W-3alyA:
undetectable		 3wg7N-3alyA:
13.55
3wg7W-3alyA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  22
GLY A  34
ALA A 124
LEU A 127
GLU A 123
 None
 1.07A 4l8fB-3alyA:
undetectable		 4l8fB-3alyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  22
GLY A  34
ALA A 124
LEU A 127
GLU A 123
 None
 1.12A 4l8fB-3alyA:
undetectable		 4l8fB-3alyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  22
GLY A  34
ALA A 124
LEU A 127
GLU A 123
 None
 1.11A 4l8fD-3alyA:
undetectable		 4l8fD-3alyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  22
GLY A  34
ALA A 124
LEU A 127
GLU A 123
 None
 1.14A 4l8fD-3alyA:
undetectable		 4l8fD-3alyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 12 ASN A  48
GLY A  55
SER A  54
ILE A  73
GLY A   4
 None
 1.09A 4obwC-3alyA:
undetectable		 4obwC-3alyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 113
GLY A   4
ASP A 125
SER A 128
VAL A  80
 None
 1.42A 5d0yA-3alyA:
undetectable		 5d0yA-3alyA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 5 GLN A  83
ILE A  95
ILE A  96
TYR A  53
 None
 1.16A 5dnuA-3alyA:
undetectable		 5dnuA-3alyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		4 / 5 GLN A  83
ILE A  95
ILE A  96
TYR A  53
 None
 1.12A 5dnvA-3alyA:
undetectable		 5dnvA-3alyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753
(Sulfurisphaera
tokodaii) 		5 / 9 ASN A 121
ILE A  25
ILE A   3
GLU A  61
ILE A   2
 None
 1.23A 6hloA-3alyA:
undetectable		 6hloA-3alyA:
14.87