SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3am6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1fm6A-3am6A: undetectable	1fm6A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM9_A_9CRA201_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.95A	1fm9A-3am6A: undetectable	1fm9A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K74_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.95A	1k74A-3am6A: undetectable	1k74A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_A_HSMA401_1 (NITROPHORIN 1)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	4 / 4	ASP A 111 LEU A 91 LEU A 88 LEU A 90	None	1.24A	1u18A-3am6A: undetectable	1u18A-3am6A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_A_URFA999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	4 / 5	ALA A 12 TYR A 56 ILE A 15 ASP A 207	None None None RET A 301 ( 4.1A)	1.22A	1upfA-3am6A: undetectable	1upfA-3am6A: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.01A	1xdkA-3am6A: undetectable	1xdkA-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.01A	1xdkE-3am6A: undetectable	1xdkE-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_A_9CRA201_1 (RXR-LIKE PROTEIN)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.88A	1xiuA-3am6A: undetectable	1xiuA-3am6A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_B_9CRB202_1 (RXR-LIKE PROTEIN)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.90A	1xiuB-3am6A: undetectable	1xiuB-3am6A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_A_9CRA801_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1xlsA-3am6A: undetectable	1xlsA-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_B_9CRB802_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.93A	1xlsB-3am6A: undetectable	1xlsB-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_C_9CRC803_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.93A	1xlsC-3am6A: undetectable	1xlsC-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_D_9CRD804_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1xlsD-3am6A: undetectable	1xlsD-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_A_STIA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	4 / 6	LEU A 209 VAL A 196 VAL A 184 ILE A 201	None	0.97A	2hyyA-3am6A: undetectable	2hyyA-3am6A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZU_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.02A	3dzuA-3am6A: undetectable	3dzuA-3am6A: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZY_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.04A	3dzyA-3am6A: undetectable	3dzyA-3am6A: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OAP_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.90A	3oapA-3am6A: undetectable	3oapA-3am6A: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.89A	3uvvB-3am6A: undetectable	3uvvB-3am6A: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT8_A_TMQA302_1 (RV2671)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 201 GLY A 9 ALA A 12 ARG A 78 GLU A 199	None	1.12A	4xt8A-3am6A: undetectable	4xt8A-3am6A: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VW9_A_NCAA403_0 (FERREDOXIN--NADP REDUCTASE)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 8	THR A 8 GLY A 9 ALA A 12 GLU A 199 SER A 195	None	1.38A	5vw9A-3am6A: undetectable	5vw9A-3am6A: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.97A	5z12B-3am6A: undetectable	5z12B-3am6A: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_C_9CRC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.91A	5z12C-3am6A: undetectable	5z12C-3am6A: 15.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1fm6A-3am6A:undetectable","1fm6A-3am6A:21.85"],["1FM9_A_9CRA201_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.95A","1fm9A-3am6A:undetectable","1fm9A-3am6A:21.85"],["1K74_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.95A","1k74A-3am6A:undetectable","1k74A-3am6A:21.85"],["1U18_A_HSMA401_1","NITROPHORIN 1","3am6","RHODOPSIN-2","Acetabularia acetabulum",4,"ASP A 111;LEU A  91;LEU A  88;LEU A  90","None","1.24A","1u18A-3am6A:undetectable","1u18A-3am6A:19.33"],["1UPF_A_URFA999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","3am6","RHODOPSIN-2","Acetabularia acetabulum",4,"ALA A  12;TYR A  56;ILE A  15;ASP A 207","None;None;None;RET A 301 ( 4.1A)","1.22A","1upfA-3am6A:undetectable","1upfA-3am6A:22.39"],["1XDK_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.01A","1xdkA-3am6A:undetectable","1xdkA-3am6A:21.85"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.01A","1xdkE-3am6A:undetectable","1xdkE-3am6A:21.85"],["1XIU_A_9CRA201_1","RXR-LIKE PROTEIN","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.88A","1xiuA-3am6A:undetectable","1xiuA-3am6A:21.43"],["1XIU_B_9CRB202_1","RXR-LIKE PROTEIN","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.90A","1xiuB-3am6A:undetectable","1xiuB-3am6A:21.43"],["1XLS_A_9CRA801_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1xlsA-3am6A:undetectable","1xlsA-3am6A:21.97"],["1XLS_B_9CRB802_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.93A","1xlsB-3am6A:undetectable","1xlsB-3am6A:21.97"],["1XLS_C_9CRC803_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.93A","1xlsC-3am6A:undetectable","1xlsC-3am6A:21.97"],["1XLS_D_9CRD804_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1xlsD-3am6A:undetectable","1xlsD-3am6A:21.97"],["2HYY_A_STIA600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3am6","RHODOPSIN-2","Acetabularia acetabulum",4,"LEU A 209;VAL A 196;VAL A 184;ILE A 201","None","0.97A","2hyyA-3am6A:undetectable","2hyyA-3am6A:21.43"],["3DZU_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.02A","3dzuA-3am6A:undetectable","3dzuA-3am6A:18.61"],["3DZY_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.04A","3dzyA-3am6A:undetectable","3dzyA-3am6A:18.61"],["3OAP_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.90A","3oapA-3am6A:undetectable","3oapA-3am6A:22.61"],["3UVV_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.89A","3uvvB-3am6A:undetectable","3uvvB-3am6A:21.74"],["4XT8_A_TMQA302_1","RV2671","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A 201;GLY A   9;ALA A  12;ARG A  78;GLU A 199","None","1.12A","4xt8A-3am6A:undetectable","4xt8A-3am6A:22.07"],["5VW9_A_NCAA403_0","FERREDOXIN--NADP REDUCTASE","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"THR A   8;GLY A   9;ALA A  12;GLU A 199;SER A 195","None","1.38A","5vw9A-3am6A:undetectable","5vw9A-3am6A:19.69"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.97A","5z12B-3am6A:undetectable","5z12B-3am6A:15.11"],["5Z12_C_9CRC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.91A","5z12C-3am6A:undetectable","5z12C-3am6A:15.11"]]