SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3anp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 139
LEU C 190
ILE C 132
GLY C 155
LEU C 151
 None
 1.10A 1g50B-3anpC:
undetectable		 1g50B-3anpC:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 11 LEU C 139
LEU C 190
ILE C 132
GLY C 155
LEU C 151
 None
 1.09A 1g50C-3anpC:
undetectable		 1g50C-3anpC:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		3 / 3 ARG C  13
SER C  62
TYR C  60
 None
 0.78A 1x70A-3anpC:
undetectable		 1x70A-3anpC:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		4 / 4 LEU C  68
PRO C  82
ILE C 132
LEU C 131
 None
 1.16A 1ya4C-3anpC:
undetectable		 1ya4C-3anpC:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 158
LEU C 161
GLU C 181
SER C 165
ARG C  87
 None
 1.31A 2bm9B-3anpC:
undetectable		 2bm9B-3anpC:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		4 / 7 ARG C  16
GLU C  20
ALA C  39
ALA C  38
 None
 0.98A 2zgwA-3anpC:
undetectable		 2zgwA-3anpC:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 139
ARG C 196
ILE C 132
GLY C 155
LEU C 151
 None
 1.05A 3q95A-3anpC:
undetectable		 3q95A-3anpC:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 139
ARG C 196
ILE C 132
GLY C 155
LEU C 151
 None
 1.09A 3q95B-3anpC:
undetectable		 3q95B-3anpC:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 139
ARG C 196
ILE C 135
ILE C 132
LEU C 151
 None
 1.03A 4j24A-3anpC:
undetectable		 4j24A-3anpC:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 139
ARG C 196
ILE C 135
ILE C 132
LEU C 151
 None
 1.04A 4j24B-3anpC:
undetectable		 4j24B-3anpC:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 186
LEU C  65
LEU C  89
ALA C 159
LEU C 158
 None
 1.28A 4m11A-3anpC:
undetectable		 4m11A-3anpC:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		5 / 12 LEU C 186
ILE C 135
LEU C  89
ALA C 159
LEU C 158
 None
 1.09A 4o1zB-3anpC:
undetectable		 4o1zB-3anpC:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		4 / 8 GLU C 134
VAL C  72
GLY C 129
LEU C 128
 None
 1.00A 5sxqA-3anpC:
0.8		 5sxqA-3anpC:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		4 / 8 GLU C 134
VAL C  72
GLY C 129
LEU C 128
 None
 0.99A 5sxtA-3anpC:
undetectable		 5sxtA-3anpC:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		4 / 8 GLU C 134
VAL C  72
GLY C 129
LEU C 128
 None
 0.98A 5sxtB-3anpC:
undetectable		 5sxtB-3anpC:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY
(Thermus
thermophilus) 		3 / 3 ASP C 130
PHE C 123
ARG C 156
 None
 1.09A 5yw0A-3anpC:
undetectable		 5yw0A-3anpC:
23.81