SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3anv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		3 / 3 ALA A  86
VAL A 109
TRP A 134
 PLP  A 401 ( 4.1A)
None
None
 0.93A 1bdwA-3anvA:
undetectable
1bdwB-3anvA:
undetectable		 1bdwA-3anvA:
3.50
1bdwB-3anvA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 LEU A 288
LEU A 341
ALA A 342
LEU A 248
THR A 351
 None
 1.08A 1ya3C-3anvA:
undetectable		 1ya3C-3anvA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 5 SER A 226
SER A 255
THR A 222
ASN A 242
 None
None
PLP  A 401 (-3.7A)
None
 1.36A 1yvpA-3anvA:
undetectable		 1yvpA-3anvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		3 / 3 SER A 226
ASP A 247
CYH A 349
 None
None
ZN  A 451 (-2.3A)
 1.05A 2br4E-3anvA:
undetectable		 2br4E-3anvA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 11 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.07A 2f162-3anvA:
undetectable		 2f162-3anvA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 11 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.08A 2f16N-3anvA:
undetectable		 2f16N-3anvA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 LEU A 288
LEU A 341
ALA A 342
LEU A 248
THR A 351
 None
 1.11A 2oaxB-3anvA:
undetectable		 2oaxB-3anvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 PRO A  90
LEU A  69
ALA A  72
PHE A 107
 None
 1.11A 2vcvA-3anvA:
undetectable		 2vcvA-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 PRO A  90
LEU A  69
ALA A  72
PHE A 107
 None
 1.01A 2vcvG-3anvA:
undetectable		 2vcvG-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 PRO A  90
LEU A  69
ALA A  72
PHE A 107
 None
 0.99A 2vcvL-3anvA:
undetectable		 2vcvL-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		3 / 3 MET A 232
CYH A 177
PRO A 240
 None
None
PLP  A 401 (-4.9A)
 1.01A 3h52C-3anvA:
undetectable		 3h52C-3anvA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 5 TYR A 346
GLN A 249
ILE A 189
LEU A 253
 None
 1.13A 3ls4L-3anvA:
undetectable		 3ls4L-3anvA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.08A 3mg02-3anvA:
undetectable
3mg0V-3anvA:
undetectable		 3mg02-3anvA:
19.51
3mg0V-3anvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 11 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.07A 3mg0N-3anvA:
undetectable		 3mg0N-3anvA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 TYR A 358
LEU A   7
LEU A  15
PHE A 245
 None
 1.23A 3nk2X-3anvA:
undetectable		 3nk2X-3anvA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 5 ASN A 162
ALA A 161
PRO A 213
ALA A 210
 None
 1.28A 3twpD-3anvA:
undetectable		 3twpD-3anvA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 ALA A  26
ILE A 244
HIS A  47
GLY A  53
 None
 0.97A 3v4tH-3anvA:
undetectable		 3v4tH-3anvA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		3 / 3 CYH A 256
PRO A 223
ASP A 247
 None
 1.02A 4pm5A-3anvA:
undetectable		 4pm5A-3anvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.09A 4qvnV-3anvA:
undetectable
4qvnb-3anvA:
undetectable		 4qvnV-3anvA:
20.11
4qvnb-3anvA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.08A 4qvnH-3anvA:
undetectable
4qvnN-3anvA:
undetectable		 4qvnH-3anvA:
20.11
4qvnN-3anvA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 7 THR A 197
THR A 196
VAL A 173
HIS A 239
 None
None
None
PLP  A 401 (-4.4A)
 0.98A 4qwpB-3anvA:
undetectable		 4qwpB-3anvA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 5 GLY A 178
THR A 180
HIS A 176
GLY A 220
 None
None
PLP  A 401 ( 3.6A)
None
 1.15A 4v20A-3anvA:
undetectable		 4v20A-3anvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 4 LEU A 235
TYR A 243
PRO A 228
ILE A 229
 None
 1.29A 5esgA-3anvA:
0.7		 5esgA-3anvA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		4 / 8 ASP A 247
GLY A 241
THR A  46
ASN A  25
 None
PLP  A 401 (-3.4A)
None
None
 1.03A 5hwaA-3anvA:
undetectable		 5hwaA-3anvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.13A 5lf7V-3anvA:
undetectable
5lf7b-3anvA:
undetectable		 5lf7V-3anvA:
20.38
5lf7b-3anvA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.10A 5lf7H-3anvA:
undetectable
5lf7N-3anvA:
undetectable		 5lf7H-3anvA:
20.38
5lf7N-3anvA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 LEU A 104
HIS A 108
ARG A  41
PRO A  42
ILE A  64
 None
 1.31A 5uhdC-3anvA:
0.0		 5uhdC-3anvA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 LEU A 104
HIS A 108
ARG A  41
PRO A  42
ILE A  64
 None
 1.34A 5uhgC-3anvA:
0.0		 5uhgC-3anvA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_A_NCTA501_1
(AMINE OXIDASE)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 10 LEU A  55
GLU A 362
THR A  20
TRP A 370
ALA A 368
 None
 1.49A 6c71A-3anvA:
0.0		 6c71A-3anvA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 10 GLY A  53
GLY A  52
ALA A  56
PRO A  42
GLY A  59
 None
 1.09A 6e5zA-3anvA:
undetectable		 6e5zA-3anvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		3 / 3 TYR A 246
ASP A 247
GLN A 250
 None
 0.95A 6g1pA-3anvA:
undetectable		 6g1pA-3anvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.10A 6hwdV-3anvA:
undetectable
6hwdb-3anvA:
undetectable		 6hwdV-3anvA:
13.30
6hwdb-3anvA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3anv D-SERINE DEHYDRATASE
(Gallus
gallus) 		5 / 12 THR A 197
THR A 195
ALA A 199
GLY A 220
ALA A 175
 None
 1.10A 6hwdH-3anvA:
undetectable
6hwdN-3anvA:
undetectable		 6hwdH-3anvA:
13.30
6hwdN-3anvA:
15.52