SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3anw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 VAL B  10
TRP B  30
PHE B  80
GLU B  28
 None
 1.16A 1om5A-3anwB:
undetectable
1om5B-3anwB:
undetectable		 1om5A-3anwB:
16.14
1om5B-3anwB:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 TRP B  30
PHE B  80
GLU B  28
VAL B  10
 None
 1.19A 1rs6A-3anwB:
undetectable
1rs6B-3anwB:
undetectable		 1rs6A-3anwB:
16.14
1rs6B-3anwB:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 VAL B  10
TRP B  30
PHE B  80
GLU B  28
 None
 1.18A 2g6hA-3anwB:
undetectable
2g6hB-3anwB:
undetectable		 2g6hA-3anwB:
16.95
2g6hB-3anwB:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 VAL B  40
VAL B  25
ASP B  23
VAL B  10
 None
 0.97A 2qbnA-3anwB:
undetectable		 2qbnA-3anwB:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		3 / 3 PRO A 168
GLY A 150
TYR A 156
 None
 0.72A 2vouA-3anwA:
undetectable		 2vouA-3anwA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		3 / 3 PRO A 168
GLY A 150
TYR A 156
 None
 0.65A 2vouB-3anwA:
undetectable		 2vouB-3anwA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		3 / 3 PRO A 168
GLY A 150
TYR A 156
 None
 0.66A 2vouC-3anwA:
undetectable		 2vouC-3anwA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		5 / 12 ARG A 178
GLY A 172
LYS A 136
ARG A 102
TYR A 156
 None
 1.28A 3a27A-3anwA:
undetectable		 3a27A-3anwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 ILE A 141
LEU A 145
PHE A 159
THR A 169
 None
 1.05A 3ag2N-3anwA:
undetectable
3ag2W-3anwA:
undetectable		 3ag2N-3anwA:
16.15
3ag2W-3anwA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 ILE A 141
LEU A 145
PHE A 159
THR A 169
 None
 1.04A 3ag4N-3anwA:
undetectable
3ag4W-3anwA:
undetectable		 3ag4N-3anwA:
16.15
3ag4W-3anwA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 TRP B  30
PHE B  80
GLU B  28
VAL B  10
 None
 1.19A 3b3pA-3anwB:
undetectable
3b3pB-3anwB:
undetectable		 3b3pA-3anwB:
16.14
3b3pB-3anwB:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 VAL B  10
TRP B  30
PHE B  80
GLU B  28
 None
 1.17A 3nlqA-3anwB:
undetectable
3nlqB-3anwB:
undetectable		 3nlqA-3anwB:
16.95
3nlqB-3anwB:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		3 / 3 GLU B  61
TYR B  75
GLU B 146
 None
 0.80A 4ryaA-3anwB:
undetectable		 4ryaA-3anwB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 8 TRP B  30
PHE B  80
GLU B  28
VAL B  10
 None
 1.28A 4uchA-3anwB:
undetectable
4uchB-3anwB:
undetectable		 4uchA-3anwB:
16.26
4uchB-3anwB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 6 GLU B  76
PHE B  80
TYR B  83
HIS B   0
 None
 1.41A 4uciA-3anwB:
undetectable		 4uciA-3anwB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 GLU B  76
PHE B  80
TYR B  83
HIS B   0
 None
 1.43A 4uciB-3anwB:
undetectable		 4uciB-3anwB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 TRP B  30
PHE B  80
GLU B  28
VAL B  10
 None
 1.11A 4v3wA-3anwB:
undetectable
4v3wB-3anwB:
undetectable		 4v3wA-3anwB:
16.14
4v3wB-3anwB:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_I_DIFI1006_1
(SERUM ALBUMIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		5 / 10 PHE A  26
LEU A  10
ILE A  70
SER A  65
ALA A  63
 None
 1.43A 4z69I-3anwA:
3.9		 4z69I-3anwA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 6 ILE A 141
LEU A 145
PHE A 159
THR A 169
 None
 0.98A 5b1aN-3anwA:
undetectable
5b1aW-3anwA:
undetectable		 5b1aN-3anwA:
16.15
5b1aW-3anwA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		5 / 12 GLY A 157
ILE A 171
GLY A  85
ALA A 165
ILE A 167
 None
 0.89A 5kb6B-3anwA:
undetectable		 5kb6B-3anwA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3anw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermococcus
kodakarensis) 		4 / 7 VAL B  10
TRP B  30
PHE B  80
GLU B  28
 None
 1.20A 6auuA-3anwB:
undetectable
6auuB-3anwB:
undetectable		 6auuA-3anwB:
18.97
6auuB-3anwB:
18.97